PML targeting eradicates quiescent leukaemia-initiating cells K Ito, R Bernardi, A Morotti, S Matsuoka, G Saglio, Y Ikeda, J Rosenblatt, ... Nature 453 (7198), 1072-1078, 2008 | 702 | 2008 |
Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort study F Passamonti, C Cattaneo, L Arcaini, R Bruna, M Cavo, F Merli, ... The Lancet Haematology 7 (10), e737-e745, 2020 | 574 | 2020 |
K252a inhibits the oncogenic properties of Met, the HGF receptor A Morotti, S Mila, P Accornero, E Tagliabue, C Ponzetto Oncogene 21 (32), 4885-4893, 2002 | 198 | 2002 |
Activation of NF-κB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis M Müller, A Morotti, C Ponzetto Molecular and Cellular Biology 22 (4), 1060-1072, 2002 | 152 | 2002 |
Identification of DOK genes as lung tumor suppressors AH Berger, M Niki, A Morotti, BS Taylor, ND Socci, A Viale, C Brennan, ... Nature genetics 42 (3), 216-223, 2010 | 136 | 2010 |
Recurrent ETNK1 mutations in atypical chronic myeloid leukemia CB Gambacorti-Passerini, C Donadoni, A Parmiani, A Pirola, S Redaelli, ... Blood, The Journal of the American Society of Hematology 125 (3), 499-503, 2015 | 132 | 2015 |
PCSK9 biology and its role in atherothrombosis C Barale, E Melchionda, A Morotti, I Russo International journal of molecular sciences 22 (11), 5880, 2021 | 121 | 2021 |
The NF-κB pathway blockade by the IKK inhibitor PS1145 can overcome imatinib resistance D Cilloni, F Messa, F Arruga, I Defilippi, A Morotti, E Messa, S Carturan, ... Leukemia 20 (1), 61-67, 2006 | 120 | 2006 |
SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub R Piazza, V Magistroni, S Redaelli, M Mauri, L Massimino, A Sessa, ... Nature communications 9 (1), 2192, 2018 | 90 | 2018 |
The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis F Fusella, L Seclì, E Busso, A Krepelova, E Moiso, S Rocca, L Conti, ... Nature communications 8 (1), 1636, 2017 | 87 | 2017 |
BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP A Morotti, C Panuzzo, S Crivellaro, B Pergolizzi, U Familiari, AH Berger, ... Leukemia 28 (6), 1326-1333, 2014 | 85 | 2014 |
Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones G Carrà, C Panuzzo, D Torti, G Parvis, S Crivellaro, U Familiari, M Volante, ... Oncotarget 8 (22), 35508-35522, 2017 | 81 | 2017 |
Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-κB in AML carrying NPM1 mutations D Cilloni, F Messa, V Rosso, F Arruga, I Defilippi, S Carturan, R Catalano, ... Leukemia 22 (6), 1234-1240, 2008 | 74 | 2008 |
P53 vs NF-κB: the role of nuclear factor-kappa B in the regulation of p53 activity and vice versa G Carrà, MF Lingua, B Maffeo, R Taulli, A Morotti Cellular and Molecular Life Sciences 77, 4449-4458, 2020 | 70 | 2020 |
NF‐kB inhibition as a strategy to enhance etoposide‐induced apoptosis in K562 cell line A Morotti, D Cilloni, M Pautasso, F Messa, F Arruga, I Defilippi, S Carturan, ... American journal of hematology 81 (12), 938-945, 2006 | 65 | 2006 |
Platelet function and activation markers in primary hypercholesterolemia treated with anti-PCSK9 monoclonal antibody: A 12-month follow-up C Barale, K Bonomo, C Frascaroli, A Morotti, A Guerrasio, F Cavalot, ... Nutrition, Metabolism and Cardiovascular Diseases 30 (2), 282-291, 2020 | 62 | 2020 |
Kinase-inhibitor–insensitive cancer stem cells in chronic myeloid leukemia A Morotti, C Panuzzo, C Fava, G Saglio Expert Opinion on Biological Therapy 14 (3), 287-299, 2014 | 57 | 2014 |
HHV8-positive, HIV-negative multicentric Castleman’s disease: early and sustained complete remission with rituximab therapy without reactivation of Kaposi sarcoma P Nicoli, U Familiari, M Bosa, T Allice, F Mete, A Morotti, D Cilloni, ... International journal of hematology 90, 392-396, 2009 | 57 | 2009 |
Valproate enhances imatinib‐induced growth arrest and apoptosis in chronic myeloid leukemia cells A Morotti, D Cilloni, F Messa, F Arruga, I Defilippi, S Carturan, R Catalano, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2006 | 48 | 2006 |
BCR-ABL inactivates cytosolic PTEN through Casein Kinase II mediated tail phosphorylation A Morotti, C Panuzzo, S Crivellaro, G Carrà, C Fava, A Guerrasio, ... Cell Cycle 14 (7), 973-979, 2015 | 47 | 2015 |