Targeting protein–protein interactions as an anticancer strategy AA Ivanov, FR Khuri, H Fu Trends in pharmacological sciences 34 (7), 393-400, 2013 | 450 | 2013 |
The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, ... Nature communications 8 (1), 14356, 2017 | 287 | 2017 |
An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 171 | 2021 |
Development of selective agonists and antagonists of P2Y receptors KA Jacobson, AA Ivanov, S de Castro, TK Harden, H Ko Purinergic signalling 5, 75-89, 2009 | 150 | 2009 |
YAP1 expression in SCLC defines a distinct subtype with T-cell–inflamed phenotype TK Owonikoko, B Dwivedi, Z Chen, C Zhang, B Barwick, V Ernani, ... Journal of Thoracic Oncology 16 (3), 464-476, 2021 | 137 | 2021 |
Evaluation of Homology Modeling of G-Protein-Coupled Receptors in Light of the A2A Adenosine Receptor Crystallographic Structure AA Ivanov, D Barak, KA Jacobson Journal of medicinal chemistry 52 (10), 3284-3292, 2009 | 107 | 2009 |
Structure−Activity Relationship of Uridine 5‘-Diphosphoglucose Analogues as Agonists of the Human P2Y14 Receptor H Ko, I Fricks, AA Ivanov, TK Harden, KA Jacobson Journal of medicinal chemistry 50 (9), 2030-2039, 2007 | 77 | 2007 |
Agonists and antagonists for P2 receptors KA Jacobson, S Costanzi, BV Joshi, P Besada, DH Shin, H Ko, AA Ivanov, ... Purinergic Signalling in Neuron–Glia Interactions: Novartis Foundation …, 2006 | 73 | 2006 |
Molecular Modeling of the Human P2Y2 Receptor and Design of a Selective Agonist, 2‘-Amino-2‘-deoxy-2-thiouridine 5‘-Triphosphate AA Ivanov, H Ko, L Cosyn, S Maddileti, P Besada, I Fricks, S Costanzi, ... Journal of medicinal chemistry 50 (6), 1166-1176, 2007 | 69 | 2007 |
Medicinal Chemistry of the A3 Adenosine Receptor: Agonists, Antagonists, and Receptor Engineering KA Jacobson, AM Klutz, DK Tosh, AA Ivanov, D Preti, PG Baraldi Adenosine Receptors in Health and Disease, 123-159, 2009 | 63 | 2009 |
Structure−Activity Relationships of 2,N6,5‘-Substituted Adenosine Derivatives with Potent Activity at the A2B Adenosine Receptor H Adachi, KK Palaniappan, AA Ivanov, N Bergman, ZG Gao, KA Jacobson Journal of medicinal chemistry 50 (8), 1810-1827, 2007 | 62 | 2007 |
Structure activity and molecular modeling analyses of ribose-and base-modified uridine 5′-triphosphate analogues at the human P2Y2 and P2Y4 receptors KA Jacobson, S Costanzi, AA Ivanov, S Tchilibon, P Besada, ZG Gao, ... Biochemical pharmacology 71 (4), 540-549, 2006 | 59 | 2006 |
The OncoPPi Portal: an integrative resource to explore and prioritize protein–protein interactions for cancer target discovery AA Ivanov, B Revennaugh, L Rusnak, V Gonzalez-Pecchi, X Mo, ... Bioinformatics 34 (7), 1183-1191, 2018 | 52 | 2018 |
Functionalized Congeners of A3 Adenosine Receptor-Selective Nucleosides Containing a Bicyclo[3.1.0]hexane Ring System DK Tosh, M Chinn, AA Ivanov, AM Klutz, ZG Gao, KA Jacobson Journal of medicinal chemistry 52 (23), 7580-7592, 2009 | 49 | 2009 |
Defining the nucleotide binding sites of P2Y receptors using rhodopsin-based homology modeling AA Ivanov, S Costanzi, KA Jacobson Journal of computer-aided molecular design 20, 417-426, 2006 | 46 | 2006 |
In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer CL Grzeskowiak, ST Kundu, X Mo, AA Ivanov, O Zagorodna, H Lu, ... Nature communications 9 (1), 2732, 2018 | 45 | 2018 |
Molecular modeling of a PAMAM-CGS21680 dendrimer bound to an A2A adenosine receptor homodimer AA Ivanov, KA Jacobson Bioorganic & medicinal chemistry letters 18 (15), 4312-4315, 2008 | 42 | 2008 |
Molecular Modeling and Molecular Dynamics Simulation of the Human A2B Adenosine Receptor. The Study of the Possible Binding Modes of the A2B Receptor … AA Ivanov, II Baskin, VA Palyulin, L Piccagli, PG Baraldi, NS Zefirov Journal of medicinal chemistry 48 (22), 6813-6820, 2005 | 41 | 2005 |
Molecular recognition in the P2Y14 receptor: probing the structurally permissive terminal sugar moiety of uridine-5′-diphosphoglucose H Ko, A Das, RL Carter, IP Fricks, Y Zhou, AA Ivanov, A Melman, BV Joshi, ... Bioorganic & medicinal chemistry 17 (14), 5298-5311, 2009 | 39 | 2009 |
Design, synthesis, and bioactivity of putative tubulin ligands with adamantane core ON Zefirova, EV Nurieva, H Lemcke, AA Ivanov, DV Shishov, DG Weiss, ... Bioorganic & medicinal chemistry letters 18 (18), 5091-5094, 2008 | 39 | 2008 |