Osteoarthritis: toward a comprehensive understanding of pathological mechanism DI Chen, J Shen, W Zhao, T Wang, L Han, JL Hamilton, HJ Im Bone research 5 (1), 1-13, 2017 | 1121 | 2017 |
MMP13 is a critical target gene during the progression of osteoarthritis M Wang, ER Sampson, H Jin, J Li, QH Ke, HJ Im, D Chen Arthritis research & therapy 15, 1-11, 2013 | 534 | 2013 |
A current review of molecular mechanisms regarding osteoarthritis and pain AS Lee, MB Ellman, D Yan, JS Kroin, BJ Cole, AJ van Wijnen, HJ Im Gene 527 (2), 440-447, 2013 | 525 | 2013 |
Repetitive mechanical stretching modulates IL-1β induced COX-2, MMP-1 expression, and PGE2 production in human patellar tendon fibroblasts G Yang, HJ Im, JHC Wang Gene 363, 166-172, 2005 | 367 | 2005 |
Mechanoregulation of gene expression in fibroblasts JHC Wang, BP Thampatty, JS Lin, HJ Im Gene 391 (1-2), 1-15, 2007 | 317 | 2007 |
Articular chondrocytes express the receptor for advanced glycation end products: potential role in osteoarthritis RF Loeser, RR Yammani, CS Carlson, H Chen, A Cole, HJ Im, LS Bursch, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2005 | 307 | 2005 |
The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts M Galindo, J Pratap, DW Young, H Hovhannisyan, HJ Im, JY Choi, ... Journal of Biological Chemistry 280 (21), 20274-20285, 2005 | 299 | 2005 |
NF-κB mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments JI Pulai, H Chen, HJ Im, S Kumar, C Hanning, PS Hegde, RF Loeser the Journal of Immunology 174 (9), 5781-5788, 2005 | 268 | 2005 |
MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis X Li, G Gibson, JS Kim, J Kroin, S Xu, AJ Van Wijnen, HJ Im Gene 480 (1-2), 34-41, 2011 | 266 | 2011 |
Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis M Wang, J Shen, H Jin, HJ Im, J Sandy, D Chen Annals of the New York Academy of Sciences 1240 (1), 61-69, 2011 | 254 | 2011 |
Targeting VEGF and its receptors for the treatment of osteoarthritis and associated pain JL Hamilton, M Nagao, BR Levine, D Chen, BR Olsen, HJ Im Journal of Bone and Mineral Research 31 (5), 911-924, 2016 | 249 | 2016 |
MicroRNA functions in osteogenesis and dysfunctions in osteoporosis AJ Van Wijnen, J Van De Peppel, JP Van Leeuwen, JB Lian, GS Stein, ... Current osteoporosis reports 11, 72-82, 2013 | 246 | 2013 |
HGF mediates the anti-inflammatory effects of PRP on injured tendons J Zhang, KK Middleton, FH Fu, HJ Im, JHC Wang PloS one 8 (6), e67303, 2013 | 241 | 2013 |
Fibroblast growth factor control of cartilage homeostasis MB Ellman, D Yan, K Ahmadinia, D Chen, HS An, HJ Im Journal of cellular biochemistry 114 (4), 735-742, 2013 | 238 | 2013 |
Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis MB Ellman, HS An, P Muddasani, HJ Im Gene 420 (1), 82-89, 2008 | 217 | 2008 |
Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model HJ Im, JS Kim, X Li, N Kotwal, DR Sumner, AJ Van Wijnen, FJ Davis, ... Arthritis & Rheumatism 62 (10), 2995-3005, 2010 | 211 | 2010 |
Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cδ pathways … HJ Im, P Muddasani, V Natarajan, TM Schmid, JA Block, F Davis, ... Journal of Biological Chemistry 282 (15), 11110-11121, 2007 | 211 | 2007 |
Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis X Li, M Ellman, P Muddasani, JHC Wang, G Cs‐Szabo, AJ Van Wijnen, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 196 | 2009 |
The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity M Dudek, N Gossan, N Yang, HJ Im, JPD Ruckshanthi, H Yoshitane, X Li, ... The Journal of clinical investigation 126 (1), 365-376, 2016 | 188 | 2016 |
Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis‐like phenotype in mice J Shen, J Li, B Wang, H Jin, M Wang, Y Zhang, Y Yang, HJ Im, R O'Keefe, ... Arthritis & Rheumatism 65 (12), 3107-3119, 2013 | 186 | 2013 |