| Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ... Cell metabolism 15 (1), 110-121, 2012 | 1192 | 2012 |
| The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type MO Yuneva, TWM Fan, TD Allen, RM Higashi, DV Ferraris, T Tsukamoto, ... Cell metabolism 15 (2), 157-170, 2012 | 696 | 2012 |
| Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1 MJ Seltzer, BD Bennett, AD Joshi, P Gao, AG Thomas, DV Ferraris, ... Cancer research 70 (22), 8981-8987, 2010 | 592 | 2010 |
| Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1, 2, 4-thiadiazol-2-yl) ethyl sulfide (BPTES) MM Robinson, SJ Mcbryant, T Tsukamoto, C Rojas, DV Ferraris, ... Biochemical Journal 406 (3), 407-414, 2007 | 384 | 2007 |
| Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer L Yang, T Moss, LS Mangala, J Marini, H Zhao, S Wahlig, G Armaiz‐Pena, ... Molecular systems biology 10 (5), 728, 2014 | 358 | 2014 |
| Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer JR Mesters, C Barinka, W Li, T Tsukamoto, P Majer, BS Slusher, ... The EMBO journal 25 (6), 1375-1384, 2006 | 341 | 2006 |
| Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1, 2, 4-thiadiazol-2-yl) ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors K Shukla, DV Ferraris, AG Thomas, M Stathis, B Duvall, G Delahanty, J Alt, ... Journal of medicinal chemistry 55 (23), 10551-10563, 2012 | 235 | 2012 |
| Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer A Elgogary, Q Xu, B Poore, J Alt, SC Zimmermann, L Zhao, J Fu, B Chen, ... Proceedings of the National Academy of Sciences 113 (36), E5328-E5336, 2016 | 226 | 2016 |
| Inhibition of glutaminase selectively suppresses the growth of primary acute myeloid leukemia cells with IDH mutations A Emadi, SA Jun, T Tsukamoto, AT Fathi, MD Minden, CV Dang Experimental hematology 42 (4), 247-251, 2014 | 183 | 2014 |
| Molecular mechanisms of 5-HT3 and NK1 receptor antagonists in prevention of emesis C Rojas, M Raje, T Tsukamoto, BS Slusher European journal of pharmacology 722, 26-37, 2014 | 178 | 2014 |
| Synthesis and Biological Evaluation of d-Amino Acid Oxidase Inhibitors D Ferraris, B Duvall, YS Ko, AG Thomas, C Rojas, P Majer, K Hashimoto, ... Journal of medicinal chemistry 51 (12), 3357-3359, 2008 | 163 | 2008 |
| Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor P Majer, PF Jackson, G Delahanty, BS Grella, YS Ko, W Li, Q Liu, ... Journal of medicinal chemistry 46 (10), 1989-1996, 2003 | 158 | 2003 |
| Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine K Hashimoto, Y Fujita, M Horio, S Kunitachi, M Iyo, D Ferraris, ... Biological psychiatry 65 (12), 1103-1106, 2009 | 150 | 2009 |
| Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models GD Ghadge, BS Slusher, A Bodner, MD Canto, K Wozniak, AG Thomas, ... Proceedings of the National Academy of Sciences 100 (16), 9554-9559, 2003 | 146 | 2003 |
| High-affinity near-infrared fluorescent small-molecule contrast agents for in vivo imaging of prostate-specific membrane antigen V Humblet, R Lapidus, LR Williams, T Tsukamoto, C Rojas, P Majer, B Hin, ... Molecular imaging 4 (4), 7290.2005. 05163, 2005 | 143 | 2005 |
| Arginine deprivation inhibits the Warburg effect and upregulates glutamine anaplerosis and serine biosynthesis in ASS1-deficient cancers JC Kremer, BC Prudner, SES Lange, GR Bean, MB Schultze, ... Cell reports 18 (4), 991-1004, 2017 | 138 | 2017 |
| Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II C Bařinka, M Rovenská, P Mlcochová, K Hlouchová, A Plechanovová, ... Journal of medicinal chemistry 50 (14), 3267-3273, 2007 | 128 | 2007 |
| Progress in the discovery and development of glutamate carboxypeptidase II inhibitors T Tsukamoto, KM Wozniak, BS Slusher Drug discovery today 12 (17-18), 767-776, 2007 | 123 | 2007 |
| Arginine deiminase resistance in melanoma cells is associated with metabolic reprogramming, glucose dependence, and glutamine addiction Y Long, WB Tsai, M Wangpaichitr, T Tsukamoto, N Savaraj, LG Feun, ... Molecular cancer therapeutics 12 (11), 2581-2590, 2013 | 122 | 2013 |
| Design and pharmacological activity of phosphinic acid based NAALADase inhibitors PF Jackson, KL Tays, KM Maclin, YS Ko, W Li, D Vitharana, T Tsukamoto, ... Journal of medicinal chemistry 44 (24), 4170-4175, 2001 | 121 | 2001 |
