A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation SV Fedeles, X Tian, AR Gallagher, M Mitobe, S Nishio, SH Lee, Y Cai, ... Nature genetics 43 (7), 639-647, 2011 | 281 | 2011 |
The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton AR Gallagher, A Cedzich, N Gretz, S Somlo, R Witzgall Proceedings of the National Academy of Sciences 97 (8), 4017-4022, 2000 | 240 | 2000 |
Isolated polycystic liver disease genes define effectors of polycystin-1 function W Besse, K Dong, J Choi, S Punia, SV Fedeles, M Choi, AR Gallagher, ... The Journal of clinical investigation 127 (5), 1772-1785, 2017 | 220 | 2017 |
Molecular advances in autosomal dominant polycystic kidney disease AR Gallagher, GG Germino, S Somlo Advances in chronic kidney disease 17 (2), 118-130, 2010 | 183 | 2010 |
Loss of oriented cell division does not initiate cyst formation S Nishio, X Tian, AR Gallagher, Z Yu, V Patel, P Igarashi, S Somlo Journal of the American Society of Nephrology 21 (2), 295-302, 2010 | 164 | 2010 |
Altered trafficking and stability of polycystins underlie polycystic kidney disease Y Cai, SV Fedeles, K Dong, G Anyatonwu, T Onoe, M Mitobe, JD Gao, ... The Journal of clinical investigation 124 (12), 5129-5144, 2014 | 153 | 2014 |
Polycystin-1: a master regulator of intersecting cystic pathways SV Fedeles, AR Gallagher, S Somlo Trends in molecular medicine 20 (5), 251-260, 2014 | 148 | 2014 |
Ciliary mechanisms of cyst formation in polycystic kidney disease M Ma, AR Gallagher, S Somlo Cold Spring Harbor perspectives in biology 9 (11), a028209, 2017 | 130 | 2017 |
Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1 AR Gallagher, EL Esquivel, TS Briere, X Tian, M Mitobe, LF Menezes, ... The American journal of pathology 172 (2), 417-429, 2008 | 97 | 2008 |
The reliability of electronic health record data used for obstetrical research MR Altman, K Colorafi, KB Daratha Applied Clinical Informatics 9 (01), 156-162, 2018 | 92 | 2018 |
The stumpy gene is required for mammalian ciliogenesis T Town, JJ Breunig, MR Sarkisian, C Spilianakis, AE Ayoub, X Liu, ... Proceedings of the National Academy of Sciences 105 (8), 2853-2858, 2008 | 90 | 2008 |
A truncated polycystin-2 protein causes polycystic kidney disease and retinal degeneration in transgenic rats AR Gallagher, S Hoffmann, N Brown, A Cedzich, S Meruvu, D Podlich, ... Journal of the American Society of Nephrology 17 (10), 2719-2730, 2006 | 73 | 2006 |
The rat Pkd2 protein assumes distinct subcellular distributions in different organs N Obermüller, AR Gallagher, Y Cai, N Gassler, N Gretz, S Somlo, ... American Journal of Physiology-Renal Physiology 277 (6), F914-F925, 1999 | 71 | 1999 |
Disruption of core planar cell polarity signaling regulates renal tubule morphogenesis but is not cystogenic K Kunimoto, RD Bayly, EK Vladar, T Vonderfecht, AR Gallagher, ... Current Biology 27 (20), 3120-3131. e4, 2017 | 64 | 2017 |
Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity SV Fedeles, JS So, A Shrikhande, SH Lee, AR Gallagher, CE Barkauskas, ... The Journal of clinical investigation 125 (5), 1955-1967, 2015 | 57 | 2015 |
Steviol retards renal cyst growth through reduction of CFTR expression and inhibition of epithelial cell proliferation in a mouse model of polycystic kidney disease C Yuajit, C Muanprasat, AR Gallagher, SV Fedeles, S Kittayaruksakul, ... Biochemical pharmacology 88 (3), 412-421, 2014 | 50 | 2014 |
Molecular basis of autosomal-dominant polycystic kidney disease AR Gallagher, S Hidaka, N Gretz, R Witzgall Cellular and Molecular Life Sciences CMLS 59, 682-693, 2002 | 49 | 2002 |
A novel role for the chemokine receptor Cxcr4 in kidney morphogenesis: an in vitro study J Ueland, A Yuan, A Marlier, AR Gallagher, A Karihaloo Developmental dynamics: an official publication of the American Association …, 2009 | 38 | 2009 |
Vegf as an epithelial cell morphogen modulates branching morphogenesis of embryonic kidney by directly acting on the ureteric bud A Marlier, KM Schmidt-Ott, AR Gallagher, J Barasch, A Karihaloo Mechanisms of Development 126 (3-4), 91-98, 2009 | 34 | 2009 |
Cell polarity and cystic kidney disease S Fedeles, AR Gallagher Pediatric Nephrology 28, 1161-1172, 2013 | 28 | 2013 |