Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma Y Han, Q Jia, PS Jahani, BP Hurrell, C Pan, P Huang, J Gukasyan, ... Nature communications 11 (1), 1776, 2020 | 151 | 2020 |
PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity DG Helou, P Shafiei-Jahani, R Lo, E Howard, BP Hurrell, L Galle-Treger, ... Nature communications 11 (1), 3998, 2020 | 126 | 2020 |
Dietary fiber-induced microbial short chain fatty acids suppress ILC2-dependent airway inflammation G Lewis, B Wang, P Shafiei Jahani, BP Hurrell, H Banie, ... Frontiers in immunology 10, 2051, 2019 | 120 | 2019 |
Social networking of group two innate lymphoid cells in allergy and asthma BP Hurrell, P Shafiei Jahani, O Akbari Frontiers in immunology 9, 2694, 2018 | 61 | 2018 |
Autophagy is critical for group 2 innate lymphoid cell metabolic homeostasis and effector function L Galle-Treger, BP Hurrell, G Lewis, E Howard, PS Jahani, H Banie, ... Journal of Allergy and Clinical Immunology 145 (2), 502-517. e5, 2020 | 53 | 2020 |
IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism, and ameliorates airway hyperreactivity E Howard, G Lewis, L Galle-Treger, BP Hurrell, DG Helou, ... Journal of Allergy and Clinical Immunology 147 (4), 1281-1295. e5, 2021 | 46 | 2021 |
TNFR2 signaling enhances ILC2 survival, function, and induction of airway hyperreactivity BP Hurrell, L Galle-Treger, PS Jahani, E Howard, DG Helou, H Banie, ... Cell reports 29 (13), 4509-4524. e5, 2019 | 46 | 2019 |
CD200–CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma P Shafiei-Jahani, DG Helou, BP Hurrell, E Howard, C Quach, JD Painter, ... Nature communications 12 (1), 2526, 2021 | 33 | 2021 |
DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus P Shafiei-Jahani, BP Hurrell, L Galle-Treger, DG Helou, E Howard, ... Nature communications 11 (1), 4718, 2020 | 28 | 2020 |
LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity DG Helou, P Shafiei-Jahani, BP Hurrell, JD Painter, C Quach, E Howard, ... Journal of Allergy and Clinical Immunology 149 (1), 223-236. e6, 2022 | 24 | 2022 |
Cannabinoid receptor 2 engagement promotes group 2 innate lymphoid cell expansion and enhances airway hyperreactivity BP Hurrell, DG Helou, P Shafiei-Jahani, E Howard, JD Painter, C Quach, ... Journal of Allergy and Clinical Immunology 149 (5), 1628-1642. e10, 2022 | 21 | 2022 |
Distinct roles of LFA-1 and ICAM-1 on ILC2s control lung infiltration, effector functions, and development of airway hyperreactivity BP Hurrell, E Howard, L Galle-Treger, DG Helou, P Shafiei-Jahani, ... Frontiers in immunology 11, 542818, 2020 | 21 | 2020 |
PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability BP Hurrell, DG Helou, E Howard, JD Painter, P Shafiei-Jahani, ... Nature Communications 13 (1), 5118, 2022 | 20 | 2022 |
PD-1 blockade on tumor microenvironment-resident ILC2s promotes TNF-α production and restricts progression of metastatic melanoma E Howard, BP Hurrell, DG Helou, C Quach, JD Painter, P Shafiei-Jahani, ... Frontiers in Immunology 12, 733136, 2021 | 20 | 2021 |
Autophagy impairment in liver CD11c+ cells promotes non-alcoholic fatty liver disease through production of IL-23 L Galle-Treger, DG Helou, C Quach, E Howard, BP Hurrell, GRA Muench, ... Nature Communications 13 (1), 1440, 2022 | 16 | 2022 |
Type 2 innate lymphoid cells induce CNS demyelination in an HSV-IL-2 mouse model of multiple sclerosis S Hirose, PS Jahani, S Wang, U Jaggi, K Tormanen, J Yu, M Kato, ... Iscience 23 (10), 2020 | 15 | 2020 |
Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells DG Helou, C Quach, M Fung, JD Painter, BP Hurrell, YHE Loh, E Howard, ... Journal of Allergy and Clinical Immunology 151 (2), 526-538. e8, 2023 | 11 | 2023 |
CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation P Shafiei-Jahani, DG Helou, BP Hurrell, L Galle-Treger, E Howard, ... Mucosal immunology 14 (4), 899-911, 2021 | 10 | 2021 |
A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity H Maazi, JA Hartiala, Y Suzuki, AL Crow, P Shafiei Jahani, J Lam, N Patel, ... PLoS Genetics 15 (12), e1008528, 2019 | 10 | 2019 |
Orai inhibition modulates pulmonary ILC2 metabolism and alleviates airway hyperreactivity in murine and humanized models E Howard, BP Hurrell, DG Helou, P Shafiei-Jahani, S Hasiakos, J Painter, ... Nature Communications 14 (1), 5989, 2023 | 7 | 2023 |