Metformin pathways: pharmacokinetics and pharmacodynamics L Gong, S Goswami, KM Giacomini, RB Altman, TE Klein Pharmacogenetics and genomics 22 (11), 820-827, 2012 | 605 | 2012 |
Charge variants in IgG1: isolation, characterization, in vitro binding properties and pharmacokinetics in rats LA Khawli, S Goswami, R Hutchinson, ZW Kwong, J Yang, X Wang, Z Yao, ... MAbs 2 (6), 613-624, 2010 | 439 | 2010 |
Variants in pharmacokinetic transporters and glycemic response to metformin: a Metgen meta‐analysis T Dujic, K Zhou, SW Yee, N van Leeuwen, CE de Keyser, M Javorský, ... Clinical Pharmacology & Therapeutics 101 (6), 763-772, 2017 | 115 | 2017 |
Model‐informed precision dosing at the bedside: scientific challenges and opportunities RJ Keizer, R Ter Heine, A Frymoyer, LJ Lesko, R Mangat, S Goswami CPT: pharmacometrics & systems pharmacology 7 (12), 785-787, 2018 | 114 | 2018 |
Metabolomic and genome‐wide association studies reveal potential endogenous biomarkers for OATP1B1 SW Yee, MM Giacomini, CH Hsueh, D Weitz, X Liang, S Goswami, ... Clinical Pharmacology & Therapeutics 100 (5), 524-536, 2016 | 94 | 2016 |
Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin S Goswami, SW Yee, S Stocker, JD Mosley, M Kubo, R Castro, JA Mefford, ... Clinical Pharmacology & Therapeutics 96 (3), 370-379, 2014 | 80 | 2014 |
The effect of famotidine, a MATE1-selective inhibitor, on the pharmacokinetics and pharmacodynamics of metformin JE Hibma, AA Zur, RA Castro, MB Wittwer, RJ Keizer, SW Yee, ... Clinical pharmacokinetics 55, 711-721, 2016 | 60 | 2016 |
Individualized empiric vancomycin dosing in neonates using a model-based approach A Frymoyer, C Stockmann, AL Hersh, S Goswami, RJ Keizer Journal of the Pediatric Infectious Diseases Society 8 (2), 97-104, 2019 | 45 | 2019 |
PharmGKB summary: very important pharmacogene information for: SLC22A1 S Goswami, L Gong, K Giacomini, RB Altman, TE Klein Pharmacogenetics and genomics 24 (6), 324-328, 2014 | 36 | 2014 |
Assessment of a model-informed precision dosing platform use in routine clinical care for personalized busulfan therapy in the pediatric hematopoietic cell transplantation (HCT … P Shukla, S Goswami, RJ Keizer, BA Winger, S Kharbanda, CC Dvorak, ... Frontiers in Pharmacology 11, 888, 2020 | 32 | 2020 |
Bayesian clinical decision support-guided versus clinician-guided vancomycin dosing in attainment of targeted pharmacokinetic parameters in a paediatric population DM Hughes, S Goswami, RJ Keizer, MSA Hughes, JD Faldasz Journal of Antimicrobial Chemotherapy 75 (2), 434-437, 2020 | 26 | 2020 |
A longitudinal HbA1c model elucidates genes linked to disease progression on metformin S Goswami, SW Yee, F Xu, SB Sridhar, JD Mosley, A Takahashi, M Kubo, ... Clinical Pharmacology & Therapeutics 100 (5), 537-547, 2016 | 18 | 2016 |
Charge variants in IgG1: isolation, characterization, in vitro binding properties and pharmacokinetics in rats. MAbs 2: 613–624 LA Khawli, S Goswami, R Hutchinson, ZW Kwong, J Yang, X Wang, Z Yao, ... Article, 2010 | 7 | 2010 |
Metabolomic and genome-wide association studies reveal potential endogenous biomarkers for Oatp1b1 S Yee, MM Giacomini, CH Hsueh, D Weitz, X Liang, S Goswami, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 101 (S 1), S96-S97, 2017 | 2 | 2017 |
ASSESSMENT OF A MODEL-BASED CLINICAL DECISION SUPPORT TOOL FOR BUSULFAN IN THE PEDIATRIC HEMATOPOIETIC CELL TRANSPLANTATION POPULATION. P Shukla, S Goswami, RJ Keizer, R Mangat, J Long-Boyle CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S50-S50, 2018 | 1 | 2018 |
GENETIC VARIANTS IN TRANSCRIPTION FACTORS ARE LINKED TO THE PHARMACOKINETICS AND PHARMACODYNAMICS OF METFORMIN S Goswami, S Yee, SL Stocker, JD Mosley, M Kubo, S Maeda, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 95, S10-S11, 2014 | 1 | 2014 |
IMPLEMENTATION OF A VANCOMYCIN MODEL-BASED DOSING TOOL INTEGRATED WITHIN THE ELECTRONIC HEALTH RECORD. S Goswami, R Keizer, S Ghaskari, L Schneider, JH Faulkenberry, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S68-S68, 2018 | | 2018 |
QUANTITATIVE MODEL OF A SERUM CREATININE ELEVATION BY FAMOTIDINE, A SELECTIVE MATE1 TRANSPORTER INHIBITOR, IN HEALTHY VOLUNTEERS JE Hibma, AA Zur, RJ Keizer, RA Castro, MB Wittwer, S Goswami, ... DRUG METABOLISM REVIEWS 47, 262-263, 2015 | | 2015 |
A PHARMACOMETRICS APPROACH COMBINED WITH VARIOUS GENETIC ANALYSES UNCOVERS GENES LINKED TO THE DYNAMICS OF HBA1C. S Goswami, S Yee, J Mosley, M Hedderson, M Kabu, S Maeda, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 97, S3-S3, 2015 | | 2015 |
Novel Computational Methods to Discover Genes Linked to Drug Response S Goswami University of California, San Francisco, 2015 | | 2015 |