| The immunocompromised district: a unifying concept for lymphoedematous, herpes‐infected and otherwise damaged sites V Ruocco, G Brunetti, RV Puca, E Ruocco Journal of the European Academy of Dermatology and Venereology 23 (12), 1364 …, 2009 | 238 | 2009 |
| Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells R Puca, L Nardinocchi, D Givol, G D'Orazi Oncogene 29 (31), 4378-4387, 2010 | 178 | 2010 |
| Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs R Puca, L Nardinocchi, M Porru, AJ Simon, G Rechavi, C Leonetti, D Givol, ... Cell Cycle 10 (10), 1679-1689, 2011 | 130 | 2011 |
| Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo L Nardinocchi, V Pantisano, R Puca, M Porru, A Aiello, A Grasselli, ... PloS one 5 (12), e15048, 2010 | 128 | 2010 |
| Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis L Nardinocchi, R Puca, A Sacchi, G D'Orazi Molecular cancer 8, 1-9, 2009 | 119 | 2009 |
| HIPK2 modulates p53 activity towards pro-apoptotic transcription R Puca, L Nardinocchi, A Sacchi, G Rechavi, D Givol, G D'Orazi Molecular cancer 8, 1-14, 2009 | 102 | 2009 |
| The inhibition of KCa3. 1 channels activity reduces cell motility in glioblastoma derived cancer stem cells P Ruggieri, G Mangino, B Fioretti, L Catacuzzeno, R Puca, D Ponti, ... Public Library of Science 7 (10), e47825, 2012 | 92 | 2012 |
| Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown R Puca, L Nardinocchi, H Gal, G Rechavi, N Amariglio, E Domany, ... Cancer research 68 (10), 3707-3714, 2008 | 84 | 2008 |
| Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis R Puca, L Nardinocchi, G Starace, G Rechavi, A Sacchi, D Givol, ... Free Radical Biology and Medicine 48 (10), 1338-1346, 2010 | 82 | 2010 |
| Transcriptional regulation of hypoxia-inducible factor 1α by HIPK2 suggests a novel mechanism to restrain tumor growth L Nardinocchi, R Puca, D Guidolin, AS Belloni, G Bossi, C Michiels, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (2), 368-377, 2009 | 76 | 2009 |
| Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc R Puca, L Nardinocchi, G Bossi, A Sacchi, G Rechavi, D Givol, G D'Orazi Experimental cell research 315 (1), 67-75, 2009 | 75 | 2009 |
| Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1α L Nardinocchi, R Puca, A Sacchi, G Rechavi, D Givol, G D'Orazi PLoS One 4 (8), e6819, 2009 | 72 | 2009 |
| HIPK2--A therapeutical target to be (re) activated for tumor suppression: Role in p53 activation and HIF-1α inhibition L Nardinocchi, R Puca, D Givol, G D’Orazi Cell Cycle 9 (7), 1270-1275, 2010 | 70 | 2010 |
| Homeodomain interacting protein kinase 2: a target for Alzheimer's beta amyloid leading to misfolded p53 and inappropriate cell survival C Lanni, L Nardinocchi, R Puca, S Stanga, D Uberti, M Memo, S Govoni, ... PloS one 5 (4), e10171, 2010 | 68 | 2010 |
| Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function O Margalit, AJ Simon, E Yakubov, R Puca, A Yosepovich, C Avivi, ... International journal of cancer 131 (4), E562-E568, 2012 | 67 | 2012 |
| HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation L Nardinocchi, R Puca, G D'Orazi Aging (Albany NY) 3 (1), 33, 2011 | 65 | 2011 |
| Adjuvant drugs in autoimmune bullous diseases, efficacy versus safety: Facts and controversies AL Schiavo, RV Puca, V Ruocco, E Ruocco Clinics in dermatology 28 (3), 337-343, 2010 | 55 | 2010 |
| Extra-virgin olive oil phenols block cell cycle progression and modulate chemotherapeutic toxicity in bladder cancer cells A Coccia, L Mosca, R Puca, G Mangino, A Rossi, E Lendaro Oncology Reports 36 (6), 3095-3104, 2016 | 48 | 2016 |
| Lymphedematous areas: privileged sites for tumors, infections, and immune disorders E Ruocco, RV Puca, G Brunetti, RA Schwartz, V Ruocco International journal of dermatology 46 (6), 662, 2007 | 39 | 2007 |
| Regulation of vascular endothelial growth factor expression by homeodomain-interacting protein kinase-2 R Puca, L Nardinocchi, G D'Orazi Journal of Experimental & Clinical Cancer Research 27, 1-7, 2008 | 35 | 2008 |
