Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ... Science 324 (5928), 801-804, 2009 | 854 | 2009 |
Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis R Jayaram, S Gaonkar, P Kaur, BL Suresh, BN Mahesh, R Jayashree, ... Antimicrobial agents and chemotherapy 47 (7), 2118-2124, 2003 | 427 | 2003 |
Moxifloxacin, Ofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis: Evaluation of In Vitro and Pharmacodynamic Indices That Best Predict … RK Shandil, R Jayaram, P Kaur, S Gaonkar, BL Suresh, BN Mahesh, ... Antimicrobial agents and chemotherapy 51 (2), 576-582, 2007 | 258 | 2007 |
Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis R Jayaram, RK Shandil, S Gaonkar, P Kaur, BL Suresh, BN Mahesh, ... Antimicrobial agents and chemotherapy 48 (8), 2951-2957, 2004 | 195 | 2004 |
Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious in Vivo PS Shirude, R Shandil, C Sadler, M Naik, V Hosagrahara, S Hameed, ... Journal of Medicinal Chemistry 56 (23), 9701-9708, 2013 | 164 | 2013 |
Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis SJ Tantry, SD Markad, V Shinde, J Bhat, G Balakrishnan, AK Gupta, ... Journal of medicinal chemistry 60 (4), 1379-1399, 2017 | 114 | 2017 |
1, 4-Azaindole, a potential drug candidate for treatment of tuberculosis M Chatterji, R Shandil, MR Manjunatha, S Solapure, V Ramachandran, ... Antimicrobial agents and chemotherapy 58 (9), 5325-5331, 2014 | 106 | 2014 |
Lead optimization of 1, 4-azaindoles as antimycobacterial agents PS Shirude, RK Shandil, MR Manjunatha, C Sadler, M Panda, V Panduga, ... Journal of medicinal chemistry 57 (13), 5728-5737, 2014 | 99 | 2014 |
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity M Naik, V Humnabadkar, SJ Tantry, M Panda, A Narayan, S Guptha, ... Journal of medicinal chemistry 57 (12), 5419-5434, 2014 | 96 | 2014 |
Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis R Mishra, S Kohli, N Malhotra, P Bandyopadhyay, M Mehta, MH Munshi, ... Science translational medicine 11 (518), eaaw6635, 2019 | 91 | 2019 |
In Vitro and In Vivo Efficacy of β-Lactams against Replicating and Slowly Growing/Nonreplicating Mycobacterium tuberculosis S Solapure, N Dinesh, R Shandil, V Ramachandran, S Sharma, ... Antimicrobial agents and chemotherapy 57 (6), 2506-2510, 2013 | 78 | 2013 |
Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice D Awasthy, S Gaonkar, RK Shandil, R Yadav, S Bharath, N Marcel, ... Microbiology 155 (9), 2978-2987, 2009 | 70 | 2009 |
Whole cell screen based identification of spiropiperidines with potent antitubercular properties SJ Tantry, G Degiacomi, S Sharma, L kumar Jena, A Narayan, S Guptha, ... Bioorganic & medicinal chemistry letters 25 (16), 3234-3245, 2015 | 46 | 2015 |
Optimization of pyrrolamides as mycobacterial GyrB ATPase inhibitors: structure-activity relationship and in vivo efficacy in a mouse model of tuberculosis S Solapure, K Mukherjee, V Nandi, D Waterson, R Shandil, M Balganesh, ... Antimicrobial agents and chemotherapy 58 (1), 61, 2014 | 39 | 2014 |
Scaffold morphing to identify novel DprE1 inhibitors with antimycobacterial activity R Shandil, M Panda, C Sadler, A Ambady, V Panduga, N Kumar, ... ACS medicinal chemistry letters 10 (10), 1480, 2019 | 36 | 2019 |
Study of the Interaction between Bacteriophage T4 asiA and Escherichia coli ς70, Using the Yeast Two-Hybrid System: Neutralization of asiA Toxicity to E. coli Cells by … UK Sharma, S Ravishankar, RK Shandil, PVK Praveen, TS Balganesh Journal of bacteriology 181 (18), 5855-5859, 1999 | 36 | 1999 |
Effect of coadministration of moxifloxacin and rifampin on Mycobacterium tuberculosis in a murine aerosol infection model V Balasubramanian, S Solapure, S Gaonkar, KN Mahesh Kumar, ... Antimicrobial agents and chemotherapy 56 (6), 3054-3057, 2012 | 35 | 2012 |
High-Throughput Screen for Inhibitors of Transglycosylase and/or Transpeptidase Activities of Escherichia coli Penicillin Binding Protein 1b B Chandrakala, RK Shandil, U Mehra, S Ravishankar, P Kaur, V Usha, ... Antimicrobial agents and chemotherapy 48 (1), 30-40, 2004 | 33 | 2004 |
Pharmacokinetics and dose response of anti-TB drugs in rat infection model of tuberculosis N Kumar, KG Vishwas, M Kumar, J Reddy, M Parab, CL Manikanth, ... Tuberculosis 94 (3), 282-286, 2014 | 32 | 2014 |
Randomized trial of metformin with anti-tuberculosis drugs for early sputum conversion in adults with pulmonary tuberculosis C Padmapriydarsini, M Mamulwar, A Mohan, P Shanmugam, ... Clinical Infectious Diseases 75 (3), 425-434, 2022 | 31 | 2022 |