| The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S Y Hayashi, S Koyanagi, N Kusunose, R Okada, Z Wu, H Tozaki-Saitoh, ... Scientific reports 3 (1), 2744, 2013 | 162 | 2013 |
| cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene S Koyanagi, AM Hamdan, M Horiguchi, N Kusunose, A Okamoto, ... Journal of Biological Chemistry 286 (37), 32416-32423, 2011 | 107 | 2011 |
| Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia S Koyanagi, N Kusunose, M Taniguchi, T Akamine, Y Kanado, Y Ozono, ... Nature Communications 7 (1), 13102, 2016 | 99 | 2016 |
| Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain N Kusunose, S Koyanagi, K Hamamura, N Matsunaga, M Yoshida, ... Molecular pain 6, 1744-8069-6-83, 2010 | 82 | 2010 |
| Aryl hydrocarbon receptor-mediated Cyp1a1 expression is modulated in a CLOCK-dependent circadian manner N Tanimura, N Kusunose, N Matsunaga, S Koyanagi, S Ohdo Toxicology 290 (2-3), 203-207, 2011 | 62 | 2011 |
| Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1 A Okamura, S Koyanagi, A Dilxiat, N Kusunose, JJ Chen, N Matsunaga, ... Journal of Biological Chemistry 289 (36), 25296-25305, 2014 | 51 | 2014 |
| Intestinal expression of mouse Abcg2/breast cancer resistance protein (BCRP) gene is under control of circadian clock-activating transcription factor-4 pathway AM Hamdan, S Koyanagi, E Wada, N Kusunose, Y Murakami, ... Journal of Biological Chemistry 287 (21), 17224-17231, 2012 | 50 | 2012 |
| Periodic variation in bile acids controls circadian changes in uric acid via regulation of xanthine oxidase by the orphan nuclear receptor PPARα T Kanemitsu, Y Tsurudome, N Kusunose, M Oda, N Matsunaga, ... Journal of Biological Chemistry 292 (52), 21397-21406, 2017 | 40 | 2017 |
| Modulation of peroxisome proliferator-activated receptor-α activity by bile acids causes circadian changes in the intestinal expression of Octn1/Slc22a4 in mice E Wada, S Koyanagi, N Kusunose, T Akamine, H Masui, H Hashimoto, ... Molecular Pharmacology 87 (2), 314-322, 2015 | 40 | 2015 |
| Time-dependent interaction between differentiated embryo chondrocyte-2 and CCAAT/enhancer-binding protein α underlies the circadian expression of CYP2D6 in serum-shocked HepG2 … N Matsunaga, M Inoue, N Kusunose, K Kakimoto, K Hamamura, ... Molecular pharmacology 81 (5), 739-747, 2012 | 38 | 2012 |
| Diurnal spatial rearrangement of microglial processes through the rhythmic expression of P2Y12 receptors Y Hayashi J Neurol Disord 120, 1, 2013 | 37 | 2013 |
| Dosing time-dependent changes in the analgesic effect of pregabalin on diabetic neuropathy in mice T Akamine, S Koyanagi, N Kusunose, H Hashimoto, M Taniguchi, ... Journal of Pharmacology and Experimental Therapeutics 354 (1), 65-72, 2015 | 34 | 2015 |
| Influence of intermittent hypoxia on the signal transduction pathways to inflammatory response and circadian clock regulation N Burioka, S Koyanagi, Y Fukuoka, F Okazaki, T Fujioka, N Kusunose, ... Life sciences 85 (9-10), 372-378, 2009 | 31 | 2009 |
| Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs Y Kanado, Y Tsurudome, Y Omata, S Yasukochi, N Kusunose, T Akamine, ... Biochemical and Biophysical Research Communications 519 (3), 613-619, 2019 | 23 | 2019 |
| Mutation of the gene encoding the circadian clock component PERIOD2 in oncogenic cells confers chemoresistance by up-regulating the Aldh3a1 gene C Katamune, S Koyanagi, K Hashikawa, N Kusunose, T Akamine, ... Journal of Biological Chemistry 294 (2), 547-558, 2019 | 17 | 2019 |
| Accumulation of sorbitol in the sciatic nerve modulates circadian properties of diabetes-induced neuropathic pain hypersensitivity in a diabetic mouse model T Akamine, N Kusunose, N Matsunaga, S Koyanagi, S Ohdo Biochemical and biophysical research communications 503 (1), 181-187, 2018 | 16 | 2018 |
| Dysfunction of the circadian transcriptional factor CLOCK in mice resists chemical carcinogen-induced tumorigenesis K Hashikawa, C Katamune, N Kusunose, N Matsunaga, S Koyanagi, ... Scientific reports 7 (1), 9995, 2017 | 15 | 2017 |
| Dosing time-dependent changes in the anti-tumor effect of xCT inhibitor erastin in human breast cancer xenograft mice S Shiromizu, T Yamauchi, N Kusunose, N Matsunaga, S Koyanagi, ... Biological and Pharmaceutical Bulletin 42 (11), 1921-1925, 2019 | 12 | 2019 |
| Sulfasalazine alleviates neuropathic pain hypersensitivity in mice through inhibition of SGK-1 in the spinal cord S Yasukochi, N Kusunose, N Matsunaga, S Koyanagi, S Ohdo Biochemical pharmacology 185, 114411, 2021 | 9 | 2021 |
| Contribution of the clock gene DEC2 to VEGF mRNA upregulation by modulation of HIF1α protein levels in hypoxic MIO-M1 cells, a human cell line of retinal glial … N Kusunose, T Akamine, Y Kobayashi, S Yoshida, K Kimoto, S Yasukochi, ... Japanese Journal of Ophthalmology 62, 677-685, 2018 | 9 | 2018 |
