Post-translational modifications (PTMs), identified on endogenous huntingtin, cluster within proteolytic domains between HEAT repeats T Ratovitski, RN O’Meally, M Jiang, R Chaerkady, E Chighladze, ... Journal of proteome research 16 (8), 2692-2708, 2017 | 54 | 2017 |
Regional levels of physiological α-synuclein are directly associated with Lewy body pathology D Erskine, L Patterson, A Alexandris, PS Hanson, IG McKeith, J Attems, ... Acta neuropathologica 135, 153-154, 2018 | 40 | 2018 |
Wallerian degeneration as a therapeutic target in traumatic brain injury VE Koliatsos, AS Alexandris Current opinion in neurology 32 (6), 786-795, 2019 | 39 | 2019 |
Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury DS Welsbie, NK Ziogas, L Xu, BJ Kim, Y Ge, AK Patel, J Ryu, M Lehar, ... Molecular neurodegeneration 14, 1-18, 2019 | 31 | 2019 |
Cholinergic deficits and galaninergic hyperinnervation of the nucleus basalis of Meynert in Alzheimer’s disease and Lewy body disorders AS Alexandris, L Walker, AKL Liu, KE McAleese, M Johnson, RKB Pearce, ... Neuropathology and Applied Neurobiology 46 (3), 264-278, 2020 | 21 | 2020 |
Differential expression of galanin in the cholinergic basal forebrain of patients with Lewy body disorders A Alexandris, AKL Liu, RCC Chang, RKB Pearce, SM Gentleman Acta Neuropathologica Communications 3, 1-12, 2015 | 17 | 2015 |
Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington’s disease M Jiang, X Zhang, H Liu, J LeBron, A Alexandris, Q Peng, H Gu, F Yang, ... Human molecular genetics 29 (8), 1340-1352, 2020 | 14 | 2020 |
Protective effects of NAMPT or MAPK inhibitors and NaR on Wallerian degeneration of mammalian axons AS Alexandris, J Ryu, L Rajbhandari, R Harlan, J McKenney, Y Wang, ... Neurobiology of disease 171, 105808, 2022 | 11 | 2022 |
Traumatic axonopathy in spinal tracts after impact acceleration head injury: ultrastructural observations and evidence of SARM1-dependent axonal degeneration AS Alexandris, Y Lee, M Lehar, Z Alam, P Samineni, SJ Tripathi, J Ryu, ... Experimental neurology 359, 114252, 2023 | 10 | 2023 |
Optogenetically transduced human ES cell-derived neural progenitors and their neuronal progenies: Phenotypic characterization and responses to optical stimulation J Ryu, PFY Vincent, NK Ziogas, L Xu, S Sadeghpour, J Curtin, ... Plos one 14 (11), e0224846, 2019 | 10 | 2019 |
Traumatic axonal injury in the optic nerve: the selective role of SARM1 in the evolution of distal axonopathy AS Alexandris, Y Lee, M Lehar, Z Alam, J McKenney, D Perdomo, J Ryu, ... Journal of neurotrauma 40 (15-16), 1743-1761, 2023 | 6 | 2023 |
NAD+, Axonal Maintenance, and Neurological Disease AS Alexandris, VE Koliatsos Antioxidants & Redox Signaling 39 (16), 1167-1184, 2023 | 4 | 2023 |
Understanding and managing Gambling Disorder: An overview of recent evidence and current practices A Alexandris, N Smith, H Bowden-Jones Research and Advances in Psychiatry 2, 36-47, 2015 | 3 | 2015 |
Long-term changes in axon calibers after injury: observations on the mouse corticospinal tract AS Alexandris, Y Wang, CE Frangakis, Y Lee, J Ryu, Z Alam, VE Koliatsos International journal of molecular sciences 23 (13), 7391, 2022 | 2 | 2022 |
Dementia after traumatic brain injury: from neural mechanisms to psychiatry VE Koliatsos, V Rao, AS Alexandris Advances in Psychiatry and Behavioral Health 1 (1), 205-217, 2021 | 1 | 2021 |
A microfluidics-based phenotypic assay for the discovery of axon-protective agents: a proof of concept study J Ryu, N Ziogas, L Rajbhandari, A Alexandris, A Venkatesan, V Koliatsos JOURNAL OF NEUROTRAUMA 36 (13), A24-A24, 2019 | 1 | 2019 |
Combined mapk and nampt inhibition for treatment of neuron degeneration VE Koliatsos, A Alexandris, RYU Jiwon US Patent App. 17/570,809, 2022 | | 2022 |
DEGENERATION AND COLLATERAL PLASTICITY IN THE MURINE RETINOCOLLICULAR SYSTEM AFTER IMPACT-ACCELERATION TRAUMATIC BRAIN INJURY A Alexandris, S Tripathi, Z Alam, P Saminemi, D Welsbie, D Zack, ... JOURNAL OF NEUROTRAUMA 39 (11-12), A55-A55, 2022 | | 2022 |
BALLISTIC MODELS OF BLUNT INJURY IN THE GYRENCEPHALIC BRAIN (SWINE): AXONAL PATHOLOGY IN THE BRAIN STEM J Belamarich, A Alexandris, J Ryu, M Horsmon, S Wozniak, K Rafaels, ... JOURNAL OF NEUROTRAUMA 39 (11-12), A7-A7, 2022 | | 2022 |
Inhibition of nampt and/or sarm1 for the treatment of axonal degradation VE Koliatsos, N Ziogas, A Alexandris, RYU Jiwon US Patent App. 17/441,149, 2022 | | 2022 |