Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions J Wen, T Arakawa, JS Philo Analytical biochemistry 240 (2), 155-166, 1996 | 659 | 1996 |
Role of arginine in protein refolding, solubilization, and purification K Tsumoto, M Umetsu, I Kumagai, D Ejima, JS Philo, T Arakawa Biotechnology progress 20 (5), 1301-1308, 2004 | 618 | 2004 |
Mechanisms of protein aggregation JS Philo, T Arakawa Current pharmaceutical biotechnology 10 (4), 348-351, 2009 | 355 | 2009 |
Is any measurement method optimal for all aggregate sizes and types? JS Philo The AAPS journal 8, E564-E571, 2006 | 326 | 2006 |
A method for directly fitting the time derivative of sedimentation velocity data and an alternative algorithm for calculating sedimentation coefficient distribution functions JS Philo Analytical biochemistry 279 (2), 151-163, 2000 | 317 | 2000 |
An improved function for fitting sedimentation velocity data for low-molecular-weight solutes JS Philo Biophysical Journal 72 (1), 435-444, 1997 | 279 | 1997 |
Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interaction JS Philo, KH Aoki, T Arakawa, LO Narhi, J Wen Biochemistry 35 (5), 1681-1691, 1996 | 271 | 1996 |
The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticals T Arakawa, D Ejima, T Li, JS Philo Journal of pharmaceutical sciences 99 (4), 1674-1692, 2010 | 258 | 2010 |
Improved methods for fitting sedimentation coefficient distributions derived by time-derivative techniques JS Philo Analytical biochemistry 354 (2), 238-246, 2006 | 241 | 2006 |
Elution of antibodies from a Protein-A column by aqueous arginine solutions T Arakawa, JS Philo, K Tsumoto, R Yumioka, D Ejima Protein expression and purification 36 (2), 244-248, 2004 | 239 | 2004 |
A critical review of methods for size characterization of non-particulate protein aggregates JS Philo Current pharmaceutical biotechnology 10 (4), 359-372, 2009 | 238 | 2009 |
Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies D Ejima, K Tsumoto, H Fukada, R Yumioka, K Nagase, T Arakawa, ... Proteins: Structure, Function, and Bioinformatics 66 (4), 954-962, 2007 | 235 | 2007 |
Conformation of sLex Tetrasaccharide, Free in Solution and Bound to E-, P-, and L-Selectin, L Poppe, GS Brown, JS Philo, PV Nikrad, BH Shah Journal of the American Chemical Society 119 (7), 1727-1736, 1997 | 230 | 1997 |
Online size-exclusion high-performance liquid chromatography light scattering and differential refractometry methods to determine degree of polymer conjugation to proteins and … BS Kendrick, BA Kerwin, BS Chang, JS Philo Analytical biochemistry 299 (2), 136-146, 2001 | 150 | 2001 |
Mechanism of photoinhibition of photosynthetic water oxidation by chloride depletion and fluoride substitution: oxidation of a protein residue M Baumgarten, JS Philo, GC Dismukes Biochemistry 29 (48), 10814-10822, 1990 | 126 | 1990 |
Human Stem Cell Factor Dimer Forms a Complex with Two Molecules of the Extracellular Domain of Its Receptor, Kit (∗) JS Philo, J Wen, J Wypych, MG Schwartz, EA Mendiaz, KE Langley Journal of Biological Chemistry 271 (12), 6895-6902, 1996 | 117 | 1996 |
Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase KS Misono, JS Philo, T Arakawa, CM Ogata, Y Qiu, H Ogawa, HS Young The FEBS journal 278 (11), 1818-1829, 2011 | 116 | 2011 |
Aggregation analysis of therapeutic proteins, part 1 T Arakawa, JS Philo, D Ejima, K Tsumoto, F Arisaka BioProcess International 4 (10), 32-42, 2006 | 116 | 2006 |
High‐sensitivity magnetic susceptometer employing superconducting technology JS Philo, WM Fairbank Review of Scientific Instruments 48 (12), 1529-1536, 1977 | 106 | 1977 |
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3 T Horan, J Wen, T Arakawa, N Liu, D Brankow, S Hu, B Ratzkin, JS Philo Journal of Biological Chemistry 270 (41), 24604-24608, 1995 | 104 | 1995 |