Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting? A Dyson, M Singer Critical care medicine 37 (1), S30-S37, 2009 | 391 | 2009 |
Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl MM Cortese-Krott, GGC Kuhnle, A Dyson, BO Fernandez, M Grman, ... Proceedings of the National Academy of Sciences 112 (34), E4651-E4660, 2015 | 293 | 2015 |
Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis P Recknagel, FA Gonnert, M Westermann, S Lambeck, A Lupp, A Rudiger, ... PLoS medicine 9 (11), e1001338, 2012 | 203 | 2012 |
Cardioprotection, attenuated systemic inflammation, and survival benefit of β1-adrenoceptor blockade in severe sepsis in rats GL Ackland, ST Yao, A Rudiger, A Dyson, R Stidwill, D Poputnikov, ... Critical care medicine 38 (2), 388-394, 2010 | 194 | 2010 |
Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction AR Hall, N Burke, RK Dongworth, SB Kalkhoran, A Dyson, JM Vicencio, ... Cell death & disease 7 (5), e2238-e2238, 2016 | 186 | 2016 |
Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist AL Brame, JJ Maguire, P Yang, A Dyson, R Torella, J Cheriyan, M Singer, ... Hypertension 65 (4), 834-840, 2015 | 173 | 2015 |
The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply–demand matching M Umbrello, A Dyson, M Feelisch, M Singer Antioxidants & redox signaling 19 (14), 1690-1710, 2013 | 169 | 2013 |
Inflammation biomarkers and delirium in critically ill patients C Ritter, CD Tomasi, F Dal-Pizzol, BB Pinto, A Dyson, AS de Miranda, ... Critical care 18, 1-6, 2014 | 127 | 2014 |
Antihyperalgesic properties of the cannabinoid CT-3 in chronic neuropathic and inflammatory pain states in the rat A Dyson, M Peacock, A Chen, JP Courade, M Yaqoob, A Groarke, C Brain, ... Pain 116 (1-2), 129-137, 2005 | 109 | 2005 |
Microcirculatory dysfunction and resuscitation: why, when, and how JPR Moore, A Dyson, M Singer, J Fraser British journal of anaesthesia 115 (3), 366-375, 2015 | 97 | 2015 |
DJ-1 protects against cell death following acute cardiac ischemia–reperfusion injury RK Dongworth, UA Mukherjee, AR Hall, R Astin, SB Ong, Z Yao, A Dyson, ... Cell death & disease 5 (2), e1082-e1082, 2014 | 91 | 2014 |
Early functional and transcriptomic changes in the myocardium predict outcome in a long-term rat model of sepsis A Rudiger, A Dyson, K Felsmann, JE Carré, V Taylor, S Hughes, ... Clinical Science 124 (6), 391-401, 2013 | 89 | 2013 |
[Pyr1]Apelin-13(1–12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13 P Yang, RE Kuc, AL Brame, A Dyson, M Singer, RC Glen, J Cheriyan, ... Frontiers in Neuroscience 11, 92, 2017 | 78 | 2017 |
Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain AJ Culshaw, S Bevan, M Christiansen, P Copp, A Davis, C Davis, ... Journal of medicinal chemistry 49 (2), 471-474, 2006 | 77 | 2006 |
The metabolic phenotype of rodent sepsis: cause for concern? PS Zolfaghari, BB Pinto, A Dyson, M Singer Intensive care medicine experimental 1, 1-13, 2013 | 74 | 2013 |
Is MOF an outcome parameter or a transient, adaptive state in critical illness? N Mongardon, A Dyson, M Singer Current opinion in critical care 15 (5), 431-436, 2009 | 72 | 2009 |
Tissue oxygen monitoring in rodent models of shock A Dyson, R Stidwill, V Taylor, M Singer American Journal of Physiology-Heart and Circulatory Physiology 293 (1 …, 2007 | 72 | 2007 |
Temporal changes in tissue cardiorespiratory function during faecal peritonitis A Dyson, A Rudiger, M Singer Intensive care medicine 37, 1192-1200, 2011 | 64 | 2011 |
Microvascular and interstitial oxygen tension in the renal cortex and medulla studied in a 4-h rat model of LPS-induced endotoxemia A Dyson, R Bezemer, M Legrand, G Balestra, M Singer, C Ince Shock 36 (1), 83-89, 2011 | 59 | 2011 |
Mitochondrial physiology C Gourlay bioenergetic communications 1 (1), 1-44, 2020 | 58 | 2020 |