PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice G Poulogiannis, RE McIntyre, M Dimitriadi, JR Apps, CH Wilson, ... Proceedings of the National Academy of Sciences 107 (34), 15145-15150, 2010 | 245 | 2010 |
Wilms’ tumor: biology, diagnosis and treatment E Szychot, J Apps, K Pritchard-Jones Translational pediatrics 3 (1), 12, 2014 | 226 | 2014 |
Paracrine roles of cellular senescence in promoting tumourigenesis JM Gonzalez-Meljem, JR Apps, HC Fraser, JP Martinez-Barbera British journal of cancer 118 (10), 1283-1288, 2018 | 166 | 2018 |
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK … JR Apps, G Carreno, JM Gonzalez-Meljem, S Haston, R Guiho, ... Acta neuropathologica 135, 757-777, 2018 | 119 | 2018 |
Multiple mechanisms of MYCN dysregulation in Wilms tumour RD Williams, T Chagtai, M Alcaide-German, J Apps, J Wegert, S Popov, ... Oncotarget 6 (9), 7232, 2015 | 115 | 2015 |
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma JM Gonzalez-Meljem, S Haston, G Carreno, JR Apps, S Pozzi, C Stache, ... Nature communications 8 (1), 1819, 2017 | 102 | 2017 |
MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma S Haston, S Pozzi, G Carreno, S Manshaei, L Panousopoulos, ... Development 144 (12), 2141-2152, 2017 | 89 | 2017 |
Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours TJ Stone, A Keeley, A Virasami, W Harkness, M Tisdall, ... Acta neuropathologica 135, 115-129, 2018 | 77 | 2018 |
Intra-tumor genetic heterogeneity in Wilms tumor: clonal evolution and clinical implications GD Cresswell, JR Apps, T Chagtai, B Mifsud, CC Bentley, M Maschietto, ... EBioMedicine 9, 120-129, 2016 | 77 | 2016 |
Molecular analyses reveal inflammatory mediators in the solid component and cyst fluid of human adamantinomatous craniopharyngioma AM Donson, J Apps, AM Griesinger, V Amani, DA Witt, RCE Anderson, ... Journal of Neuropathology & Experimental Neurology 76 (9), 779-788, 2017 | 72 | 2017 |
Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors G Carreno, JR Apps, EJ Lodge, L Panousopoulos, S Haston, ... Development 144 (18), 3289-3302, 2017 | 54 | 2017 |
Imaging Invasion: Micro-CT imaging of adamantinomatous craniopharyngioma highlights cell type specific spatial relationships of tissue invasion JR Apps, JC Hutchinson, OJ Arthurs, A Virasami, A Joshi, ... Acta neuropathologica communications 4, 1-4, 2016 | 50 | 2016 |
Molecular pathology of adamantinomatous craniopharyngioma: review and opportunities for practice JR Apps, JP Martinez-Barbera Neurosurgical focus 41 (6), E4, 2016 | 43 | 2016 |
Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience GM Vujanić, JR Apps, V Moroz, F Ceroni, RD Williams, NJ Sebire, ... Pediatric blood & cancer 64 (11), e26547, 2017 | 39 | 2017 |
Contemporary biological insights and clinical management of craniopharyngioma JR Apps, HL Muller, TC Hankinson, TI Yock, JP Martinez-Barbera Endocrine reviews 44 (3), 518-538, 2023 | 31 | 2023 |
Cow’s milk allergy in children JR Apps, RM Beattie Bmj 339, 2009 | 29 | 2009 |
SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma G Carreno, JKR Boult, J Apps, JM Gonzalez-Meljem, S Haston, R Guiho, ... Endocrine-related cancer 26 (3), 355-366, 2019 | 26 | 2019 |
An overview of drug therapies used in the treatment of dystonia and spasticity in children N Tickner, JR Apps, S Keady, AG Sutcliffe Archives of Disease in Childhood-Education and Practice 97 (6), 230-235, 2012 | 24 | 2012 |
CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma JR Apps, C Stache, JM Gonzalez‐Meljem, A Gutteridge, J Chalker, ... Neuropathology and applied neurobiology 46 (5), 510, 2020 | 23 | 2020 |
Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ P Xekouki, EJ Lodge, J Matschke, A Santambrogio, JR Apps, A Sharif, ... Endocrine-related cancer 26 (1), 215-225, 2019 | 23 | 2019 |