Integrative molecular characterization of malignant pleural mesothelioma J Hmeljak, F Sanchez-Vega, KA Hoadley, J Shih, C Stewart, D Heiman, ... Cancer discovery 8 (12), 1548-1565, 2018 | 507 | 2018 |
PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D E Toska, HU Osmanbeyoglu, P Castel, C Chan, RC Hendrickson, ... Science 355 (6331), 1324-1330, 2017 | 255 | 2017 |
The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma AM Nargund, CG Pham, Y Dong, PI Wang, HU Osmangeyoglu, Y Xie, ... Cell Reports 18 (12), 2893-2906, 2017 | 183 | 2017 |
A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance Y Feng, J van der Veeken, M Shugay, EV Putintseva, HU Osmanbeyoglu, ... Nature 528 (7580), 132-136, 2015 | 168 | 2015 |
A pan-cancer analysis reveals high-frequency genetic alterations in mediators of signaling by the TGF-β superfamily A Korkut, S Zaidi, RS Kanchi, S Rao, NR Gough, A Schultz, X Li, ... Cell systems 7 (4), 422-437. e7, 2018 | 148 | 2018 |
Thin alumina nanoporous membranes for similar size biomolecule separation HU Osmanbeyoglu, TB Hur, HK Kim Journal of Membrane Science 343 (1-2), 1-6, 2009 | 143 | 2009 |
An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication TN Moiseeva, Y Yin, MJ Calderon, C Qian, S Schamus-Haynes, ... Proceedings of the National Academy of Sciences 116 (27), 13374-13383, 2019 | 131 | 2019 |
Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM-and PUMA-mediated apoptosis K Tanaka, AY Helena, S Yang, S Han, SD Selcuklu, K Kim, S Ramani, ... Cancer Cell 39 (9), 1245-1261. e6, 2021 | 76 | 2021 |
WEE1 kinase inhibitor AZD1775 induces CDK1 kinase-dependent origin firing in unperturbed G1-and S-phase cells TN Moiseeva, C Qian, N Sugitani, HU Osmanbeyoglu, CJ Bakkenist Proceedings of the National Academy of Sciences 116 (48), 23891-23893, 2019 | 72 | 2019 |
Linking signaling pathways to transcriptional programs in breast cancer HU Osmanbeyoglu, R Pelossof, JF Bromberg, CS Leslie Genome research 24 (11), 1869-1880, 2014 | 63 | 2014 |
Evaluating the Barriers to Point-of-Care Documentation for Nursing Staff A KOHLE-ERSHER, P CHATTERJEE, HU OSMANBEYOGLU, ... Computers Informatics Nursing, 2011 | 61 | 2011 |
Cancer-associated MSC drive tumor immune exclusion and resistance to immunotherapy, which can be overcome by Hedgehog inhibition S Cascio, C Chandler, L Zhang, S Sinno, B Gao, S Onkar, TC Bruno, ... Science advances 7 (46), eabi5790, 2021 | 44 | 2021 |
Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs HU Osmanbeyoglu, E Toska, C Chan, J Baselga, CS Leslie Nature communications 8 (1), 14249, 2017 | 39 | 2017 |
N-gram analysis of 970 microbial organisms reveals presence of biological language models HU Osmanbeyoglu, MK Ganapathiraju BMC bioinformatics 12, 1-12, 2011 | 31 | 2011 |
Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers HU Osmanbeyoglu, F Shimizu, A Rynne-Vidal, D Alonso-Curbelo, ... Nature communications 10 (1), 4369, 2019 | 28 | 2019 |
Ets transcription factor GABP controls T cell homeostasis and immunity CT Luo, HU Osmanbeyoglu, MH Do, MR Bivona, A Toure, D Kang, Y Xie, ... Nature Communications 8 (1), 1062, 2017 | 26 | 2017 |
Estrogen represses gene expression through reconfiguring chromatin structures HU Osmanbeyoglu, KN Lu, S Oesterreich, RS Day, PV Benos, ... Nucleic acids research 41 (17), 8061-8071, 2013 | 24 | 2013 |
Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment S Onkar, J Cui, J Zou, C Cardello, AR Cillo, MR Uddin, A Sagan, M Joy, ... Nature Cancer 4 (4), 516-534, 2023 | 21 | 2023 |
Recurrent human papillomavirus–related head and neck cancer undergoes metabolic reprogramming and is driven by oxidative phosphorylation A Vyas, RA Harbison, DL Faden, M Kubik, D Palmer, Q Zhang, ... Clinical Cancer Research 27 (22), 6250-6264, 2021 | 21 | 2021 |
Active machine learning for transmembrane helix prediction HU Osmanbeyoglu, JA Wehner, JG Carbonell, MK Ganapathiraju BMC bioinformatics 11, 1-9, 2010 | 20 | 2010 |