| Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. T Okada, Y Kawano, T Sakakibara, O Hazeki, M Ui Journal of Biological Chemistry 269 (5), 3568-3573, 1994 | 1229 | 1994 |
| Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase M Ui, T Okada, K Hazeki, O Hazeki Trends in biochemical sciences 20 (8), 303-307, 1995 | 642 | 1995 |
| Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. T Okada, L Sakuma, Y Fukui, O Hazeki, M Ui Journal of Biological Chemistry 269 (5), 3563-3567, 1994 | 521 | 1994 |
| Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis N Igarashi, T Okada, S Hayashi, T Fujita, S Jahangeer, S Nakamura Journal of Biological Chemistry 278 (47), 46832-46839, 2003 | 502 | 2003 |
| Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3 kinase F Kanai, K Ito, M Todaka, H Hayashi, S Kamohara, K Ishii, T Okada, ... Biochemical and biophysical research communications 195 (2), 762-768, 1993 | 367 | 1993 |
| Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110β is synergistically activated by the βγ subunits of G proteins and phosphotyrosyl peptide H Kurosu, T Maehama, T Okada, T Yamamoto, S Hoshino, Y Fukui, M Ui, ... Journal of Biological Chemistry 272 (39), 24252-24256, 1997 | 330 | 1997 |
| Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes T Kajimoto, T Okada, S Miya, L Zhang, S Nakamura Nature communications 4 (1), 2712, 2013 | 314 | 2013 |
| Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling. N Ninomiya, K Hazeki, Y Fukui, T Seya, T Okada, O Hazeki, M Ui Journal of Biological Chemistry 269 (36), 22732-22737, 1994 | 240 | 1994 |
| Involvement of N-terminal-extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis T Okada, G Ding, H Sonoda, T Kajimoto, Y Haga, A Khosrowbeygi, S Gao, ... Journal of Biological Chemistry 280 (43), 36318-36325, 2005 | 210 | 2005 |
| Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 2 G Ding, H Sonoda, H Yu, T Kajimoto, SK Goparaju, S Jahangeer, T Okada, ... Journal of Biological Chemistry 282 (37), 27493-27502, 2007 | 195 | 2007 |
| Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-β1 Y Kono, T Nishiuma, Y Nishimura, Y Kotani, T Okada, S Nakamura, ... American journal of respiratory cell and molecular biology 37 (4), 395-404, 2007 | 177 | 2007 |
| Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons T Kajimoto, T Okada, H Yu, SK Goparaju, S Jahangeer, S Nakamura Molecular and cellular biology 27 (9), 3429-3440, 2007 | 167 | 2007 |
| Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model T Nishiuma, Y Nishimura, T Okada, E Kuramoto, Y Kotani, S Jahangeer, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 294 (6 …, 2008 | 129 | 2008 |
| Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus T Kanno, T Nishizaki, RL Proia, T Kajimoto, S Jahangeer, T Okada, ... Neuroscience 171 (4), 973-980, 2010 | 110 | 2010 |
| Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein S Hayashi, T Okada, N Igarashi, T Fujita, S Jahangeer, S Nakamura Journal of Biological Chemistry 277 (36), 33319-33324, 2002 | 101 | 2002 |
| Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system T Okada, T Kajimoto, S Jahangeer, S Nakamura Cellular signalling 21 (1), 7-13, 2009 | 95 | 2009 |
| Hazeki, 0. & Ui, M.(1994) J T Okada, Y Kawano, T Sakakibara Biol. Chem 269, 3568-3573, 0 | 91 | |
| Down-regulation of melanogenesis by phospholipase D2 through ubiquitin proteasome-mediated degradation of tyrosinase A Kageyama, M Oka, T Okada, S Nakamura, T Ueyama, N Saito, ... Journal of Biological Chemistry 279 (26), 27774-27780, 2004 | 80 | 2004 |
| Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte–macrophage colony-stimulating factor and its relation to the cytokine-mediated … T KODAMA, K HAZEKI, O HAZEKI, T OKADA, M UI Biochemical Journal 337 (2), 201-209, 1999 | 71 | 1999 |
| δ-Catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1 T Fujita, T Okada, S Hayashi, S Jahangeer, N Miwa, S Nakamura Biochemical Journal 382 (2), 717-723, 2004 | 68 | 2004 |
