Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP–dependent proteolysis in 3-dimensional collagen matrices AN Stratman, WB Saunders, A Sacharidou, W Koh, KE Fisher, ... Blood, The Journal of the American Society of Hematology 114 (2), 237-247, 2009 | 267 | 2009 |
In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis W Koh, AN Stratman, A Sacharidou, GE Davis Methods in enzymology 443, 83-101, 2008 | 247 | 2008 |
Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting GE Davis, AN Stratman, A Sacharidou, W Koh International review of cell and molecular biology 288, 101-165, 2011 | 221 | 2011 |
Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling K Xu, A Sacharidou, S Fu, DC Chong, B Skaug, ZJ Chen, GE Davis, ... Developmental cell 20 (4), 526-539, 2011 | 185 | 2011 |
Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice AC Chan, SG Drakos, OE Ruiz, ACH Smith, CC Gibson, J Ling, SF Passi, ... The Journal of clinical investigation 121 (5), 1871-1881, 2011 | 162 | 2011 |
Endothelial lumen signaling complexes control 3D matrix–specific tubulogenesis through interdependent Cdc42-and MT1-MMP–mediated events A Sacharidou, W Koh, AN Stratman, AM Mayo, KE Fisher, GE Davis Blood, The Journal of the American Society of Hematology 115 (25), 5259-5269, 2010 | 146 | 2010 |
A protein kinase C phosphorylation motif in GLUT1 affects glucose transport and is mutated in GLUT1 deficiency syndrome EE Lee, J Ma, A Sacharidou, W Mi, VK Salato, N Nguyen, Y Jiang, ... Molecular cell 58 (5), 845-853, 2015 | 142 | 2015 |
MT1-MMP-and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices KE Fisher, A Sacharidou, AN Stratman, AM Mayo, SB Fisher, RD Mahan, ... Journal of cell science 122 (24), 4558-4569, 2009 | 140 | 2009 |
Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices A Sacharidou, AN Stratman, GE Davis Cells Tissues Organs 195 (1-2), 122-143, 2011 | 114 | 2011 |
ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene L Yuan, A Le Bras, A Sacharidou, K Itagaki, Y Zhan, M Kondo, ... Journal of Biological Chemistry 287 (9), 6582-6591, 2012 | 109 | 2012 |
Formation of endothelial lumens requires a coordinated PKCϵ-, Src-, Pak-and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation W Koh, K Sachidanandam, AN Stratman, A Sacharidou, AM Mayo, ... Journal of cell science 122 (11), 1812-1822, 2009 | 109 | 2009 |
RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG L Yuan, A Sacharidou, AN Stratman, A Le Bras, PJ Zwiers, K Spokes, ... Blood, The Journal of the American Society of Hematology 118 (4), 1145-1153, 2011 | 99 | 2011 |
Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance K Tanigaki, A Sacharidou, J Peng, KL Chambliss, IS Yuhanna, D Ghosh, ... The Journal of clinical investigation 128 (1), 309-322, 2018 | 95 | 2018 |
ApoE receptor 2 mediation of trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice V Ulrich, SE Gelber, M Vukelic, A Sacharidou, J Herz, RT Urbanus, ... Arthritis & rheumatology 68 (3), 730-739, 2016 | 87 | 2016 |
Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium A Sacharidou, KL Chambliss, V Ulrich, JE Salmon, YM Shen, J Herz, ... Blood, The Journal of the American Society of Hematology 131 (19), 2097-2110, 2018 | 67 | 2018 |
Supplementation with the sialic acid precursor N-acetyl-D-mannosamine breaks the link between obesity and hypertension J Peng, W Vongpatanasin, A Sacharidou, D Kifer, IS Yuhanna, ... Circulation 140 (24), 2005-2018, 2019 | 47 | 2019 |
New insights in the pathophysiology of antiphospholipid syndrome A Sacharidou, PW Shaul, C Mineo Seminars in thrombosis and hemostasis 44 (05), 475-482, 2018 | 45 | 2018 |
Identification of a monoclonal antibody that attenuates antiphospholipid syndrome-related pregnancy complications and thrombosis C Mineo, L Lanier, E Jung, S Sengupta, V Ulrich, A Sacharidou, ... PloS one 11 (7), e0158757, 2016 | 33 | 2016 |
Determinants for association and guide RNA-directed endonuclease cleavage by purified RNA editing complexes from Trypanosoma brucei A Hernandez, A Panigrahi, C Cifuentes-Rojas, A Sacharidou, K Stuart, ... Journal of molecular biology 381 (1), 35-48, 2008 | 29 | 2008 |
Minimal pre-mRNA substrates with natural and converted sites for full-round U insertion and U deletion RNA editing in trypanosomes C Cifuentes-Rojas, K Halbig, A Sacharidou, M De Nova-Ocampo, ... Nucleic acids research 33 (20), 6610-6620, 2005 | 25 | 2005 |