| Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses Z Huang, R Lujan, I Kadurin, VN Uebele, JJ Renger, AC Dolphin, ... Nature neuroscience 14 (4), 478-486, 2011 | 210 | 2011 |
| Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis Z Huang, MC Walker, MM Shah Journal of Neuroscience 29 (35), 10979-10988, 2009 | 209 | 2009 |
| Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells K Martinello, Z Huang, R Lujan, B Tran, M Watanabe, EC Cooper, ... Neuron 85 (2), 346-363, 2015 | 116 | 2015 |
| Prediction of drug efficacy from transcriptional profiles with deep learning J Zhu, J Wang, X Wang, M Gao, B Guo, M Gao, J Liu, Y Yu, L Wang, ... Nature biotechnology 39 (11), 1444-1452, 2021 | 113 | 2021 |
| Chromodomain Y-like protein–mediated histone crotonylation regulates stress-induced depressive behaviors Y Liu, M Li, M Fan, Y Song, H Yu, X Zhi, K Xiao, S Lai, J Zhang, X Jin, ... Biological Psychiatry 85 (8), 635-649, 2019 | 94 | 2019 |
| Direct reprogramming of fibroblasts via a chemically induced XEN-like state X Li, D Liu, Y Ma, X Du, J Jing, L Wang, B Xie, D Sun, S Sun, X Jin, ... Cell stem cell 21 (2), 264-273. e7, 2017 | 93 | 2017 |
| In vivo chemical reprogramming of astrocytes into neurons Y Ma, H Xie, X Du, L Wang, X Jin, Q Zhang, Y Han, S Sun, L Wang, X Li, ... Cell discovery 7 (1), 12, 2021 | 71 | 2021 |
| HCN and KV7 (M-) channels as targets for epilepsy treatment MM Shah, Z Huang, K Martinello Neuropharmacology 69, 75-81, 2013 | 67 | 2013 |
| Identification of key genes related to lung squamous cell carcinoma using bioinformatics analysis M Gao, W Kong, Z Huang, Z Xie International journal of molecular sciences 21 (8), 2994, 2020 | 66 | 2020 |
| Severe deficiency of the voltage-gated sodium channel NaV1. 2 elevates neuronal excitability in adult mice J Zhang, X Chen, M Eaton, J Wu, Z Ma, S Lai, A Park, TS Ahmad, Z Que, ... Cell reports 36 (5), 2021 | 65 | 2021 |
| Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence X Chi, X Jin, Y Chen, X Lu, X Tu, X Li, Y Zhang, J Lei, J Huang, Z Huang, ... Cell discovery 6 (1), 55, 2020 | 62 | 2020 |
| Closed-state inactivation and pore-blocker modulation mechanisms of human CaV2. 2 Y Dong, Y Gao, S Xu, Y Wang, Z Yu, Y Li, B Li, T Yuan, B Yang, XC Zhang, ... Cell reports 37 (5), 2021 | 58 | 2021 |
| CDYL suppresses epileptogenesis in mice through repression of axonal Nav1. 6 sodium channel expression Y Liu, S Lai, W Ma, W Ke, C Zhang, S Liu, Y Zhang, F Pei, S Li, M Yi, ... Nature communications 8 (1), 355, 2017 | 55 | 2017 |
| Deficiency of anti-inflammatory cytokine IL-4 leads to neural hyperexcitability and aggravates cerebral ischemia–reperfusion injury X Chen, J Zhang, Y Song, P Yang, Y Yang, Z Huang, K Wang Acta Pharmaceutica Sinica B 10 (9), 1634-1645, 2020 | 50 | 2020 |
| Mg2+ block properties of triheteromeric GluN1–GluN2B–GluN2D NMDA receptors on neonatal rat substantia nigra pars compacta dopaminergic neurones Z Huang, AJ Gibb The Journal of physiology 592 (10), 2059-2078, 2014 | 45 | 2014 |
| TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels Z Huang, R Lujan, J Martinez-Hernandez, AS Lewis, DM Chetkovich, ... Journal of Neuroscience 32 (42), 14835-14848, 2012 | 41 | 2012 |
| Structure, gating, and pharmacology of human CaV3.3 channel L He, Z Yu, Z Geng, Z Huang, C Zhang, Y Dong, Y Gao, Y Wang, Q Chen, ... Nature communications 13 (1), 2084, 2022 | 39 | 2022 |
| Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1. 2-L1342P genetic variant Z Que, MI Olivero-Acosta, J Zhang, M Eaton, AM Tukker, X Chen, J Wu, ... Journal of Neuroscience 41 (49), 10194-10208, 2021 | 38 | 2021 |
| Generation and basic characterization of a gene‐trap knockout mouse model of Scn2a with a substantial reduction of voltage‐gated sodium channel Nav1.2 … M Eaton, J Zhang, Z Ma, AC Park, E Lietzke, CM Romero, Y Liu, ... Genes, Brain and Behavior 20 (4), e12725, 2021 | 25 | 2021 |
| HCN1 channels reduce the rate of exocytosis from a subset of cortical synaptic terminals Z Huang, G Li, C Aguado, R Lujan, MM Shah Scientific reports 7 (1), 40257, 2017 | 25 | 2017 |
