Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities M Bäck, A Yurdagul Jr, I Tabas, K Öörni, PT Kovanen Nature Reviews Cardiology 16 (7), 389-406, 2019 | 1204 | 2019 |
Efferocytosis in health and disease AC Doran, A Yurdagul Jr, I Tabas Nature Reviews Immunology 20 (4), 254-267, 2020 | 640 | 2020 |
Regulatory T cells promote macrophage efferocytosis during inflammation resolution JD Proto, AC Doran, G Gusarova, A Yurdagul, E Sozen, M Subramanian, ... Immunity 49 (4), 666-677. e6, 2018 | 315 | 2018 |
Macrophage metabolism of apoptotic cell-derived arginine promotes continual efferocytosis and resolution of injury A Yurdagul, M Subramanian, X Wang, SB Crown, OR Ilkayeva, L Darville, ... Cell metabolism 31 (3), 518-533. e10, 2020 | 312 | 2020 |
Mitochondrial fission promotes the continued clearance of apoptotic cells by macrophages Y Wang, M Subramanian, A Yurdagul, VC Barbosa-Lorenzi, B Cai, ... cell 171 (2), 331-345. e22, 2017 | 307 | 2017 |
Mechanisms and consequences of defective efferocytosis in atherosclerosis A Yurdagul Jr, AC Doran, B Cai, G Fredman, IA Tabas Frontiers in cardiovascular medicine 4, 86, 2018 | 265 | 2018 |
Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes SD Funk, A Yurdagul Jr, AW Orr International journal of vascular medicine 2012 (1), 569654, 2012 | 243 | 2012 |
The arterial microenvironment: the where and why of atherosclerosis A Yurdagul Jr, AC Finney, MD Woolard, AW Orr Biochemical Journal 473 (10), 1281-1295, 2016 | 208 | 2016 |
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice W Tao, A Yurdagul Jr, N Kong, W Li, X Wang, AC Doran, C Feng, J Wang, ... Science translational medicine 12 (553), eaay1063, 2020 | 157 | 2020 |
Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype AW Orr, MY Lee, JA Lemmon, A Yurdagul Jr, MF Gomez, ... Arteriosclerosis, thrombosis, and vascular biology 29 (2), 225-231, 2009 | 145 | 2009 |
Efferocytosis induces macrophage proliferation to help resolve tissue injury BD Gerlach, PB Ampomah, A Yurdagul, C Liu, MC Lauring, X Wang, ... Cell metabolism 33 (12), 2445-2463. e8, 2021 | 144 | 2021 |
α5β1 integrin signaling mediates oxidized low-density lipoprotein–induced inflammation and early atherosclerosis A Yurdagul Jr, J Green, P Albert, MC McInnis, AP Mazar, AW Orr Arteriosclerosis, thrombosis, and vascular biology 34 (7), 1362-1373, 2014 | 120 | 2014 |
EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis SD Funk, A Yurdagul Jr, P Albert, JG Traylor Jr, L Jin, J Chen, AW Orr Arteriosclerosis, thrombosis, and vascular biology 32 (3), 686-695, 2012 | 104 | 2012 |
αvβ3 integrins mediate flow-induced NF-κB activation, proinflammatory gene expression, and early atherogenic inflammation J Chen, J Green, A Yurdagul Jr, P Albert, MC McInnis, AW Orr The American journal of pathology 185 (9), 2575-2589, 2015 | 91 | 2015 |
Matrix-specific protein kinase A signaling regulates p21-activated kinase activation by flow in endothelial cells SD Funk, A Yurdagul Jr, JM Green, KA Jhaveri, MA Schwartz, AW Orr Circulation research 106 (8), 1394-1403, 2010 | 77 | 2010 |
Endothelial FN (Fibronectin) deposition by α5β1 integrins drives atherogenic inflammation Z Al-Yafeai, A Yurdagul Jr, JM Peretik, M Alfaidi, PA Murphy, AW Orr Arteriosclerosis, thrombosis, and vascular biology 38 (11), 2601-2614, 2018 | 73 | 2018 |
Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution PB Ampomah, B Cai, SR Sukka, BD Gerlach, A Yurdagul Jr, X Wang, ... Nature metabolism 4 (4), 444-457, 2022 | 71 | 2022 |
Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression A Yurdagul Jr, FJ Sulzmaier, XL Chen, CB Pattillo, DD Schlaepfer, AW Orr Journal of cell science 129 (8), 1580-1591, 2016 | 70 | 2016 |
EphA2 expression regulates inflammation and fibroproliferative remodeling in atherosclerosis AC Finney, SD Funk, JM Green, A Yurdagul Jr, MA Rana, R Pistorius, ... Circulation 136 (6), 566-582, 2017 | 67 | 2017 |
Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages X Huang, C Liu, N Kong, Y Xiao, A Yurdagul Jr, I Tabas, W Tao Nature protocols 17 (3), 748-780, 2022 | 66 | 2022 |