Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells W Yan, X Wu, W Zhou, MY Fong, M Cao, J Liu, X Liu, CH Chen, O Fadare, ... Nature cell biology 20 (5), 597-609, 2018 | 348 | 2018 |
Chemotherapy-Induced Extracellular Vesicle miRNAs Promote Breast Cancer Stemness by Targeting ONECUT2 M Shen, C Dong, X Ruan, W Yan, M Cao, D Pizzo, X Wu, L Yang, L Liu, ... Cancer research 79 (14), 3608-3621, 2019 | 160 | 2019 |
Immune cell-derived exosomes in the cancer-immunity cycle W Yan, S Jiang Trends in cancer 6 (6), 506-517, 2020 | 110 | 2020 |
Let-7 suppresses B cell activation through restricting the availability of necessary nutrients S Jiang, W Yan, SE Wang, D Baltimore Cell metabolism 27 (2), 393-403. e4, 2018 | 85 | 2018 |
Succinate in the cancer–immune cycle S Jiang, W Yan Cancer letters 390, 45-47, 2017 | 81 | 2017 |
Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts X Liu, M Cao, M Palomares, X Wu, A Li, W Yan, MY Fong, WC Chan, ... Breast Cancer Research 20, 1-12, 2018 | 67 | 2018 |
Chemotherapy induces breast cancer stemness in association with dysregulated monocytosis L Liu, L Yang, W Yan, J Zhai, DP Pizzo, P Chu, AR Chin, M Shen, C Dong, ... Clinical Cancer Research 24 (10), 2370-2382, 2018 | 47 | 2018 |
Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth M Cao, R Isaac, W Yan, X Ruan, L Jiang, Y Wan, J Wang, E Wang, ... Nature cell biology 24 (6), 954-967, 2022 | 44 | 2022 |
Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis W Yan, M Cao, X Ruan, L Jiang, S Lee, A Lemanek, M Ghassemian, ... Nature cell biology 24 (5), 793-804, 2022 | 41 | 2022 |
Acetylation of lysine ϵ-amino groups regulates aminoacyl-tRNA synthetase activity in Escherichia coli Q Ye, QQ Ji, W Yan, F Yang, ED Wang Journal of Biological Chemistry 292 (25), 10709-10722, 2017 | 20 | 2017 |
Oncolytic viruses engineered to enforce cholesterol efflux restore tumor-associated macrophage phagocytosis and anti-tumor immunity in glioblastoma S Wang, W Yan, L Kong, S Zuo, J Wu, C Zhu, H Huang, B He, J Dong, ... Nature Communications 14 (1), 4367, 2023 | 19 | 2023 |
Cancer‐secreted miRNAs regulate amino‐acid‐induced mTORC1 signaling and fibroblast protein synthesis MY Fong, W Yan, M Ghassemian, X Wu, X Zhou, M Cao, L Jiang, J Wang, ... EMBO reports 22 (2), e51239, 2021 | 16 | 2021 |
Polarized secretion of extracellular vesicles by mammary epithelia AR Chin, W Yan, M Cao, X Liu, SE Wang Journal of mammary gland biology and neoplasia 23, 165-176, 2018 | 16 | 2018 |
A naturally occurring nonapeptide functionally compensates for the CP1 domain of leucyl-tRNA synthetase to modulate aminoacylation activity M Tan, W Yan, RJ Liu, M Wang, X Chen, XL Zhou, ED Wang Biochemical Journal 443 (2), 477-484, 2012 | 15 | 2012 |
The Yin and Yang of tRNA: proper binding of acceptor end determines the catalytic balance of editing and aminoacylation M Tan, M Wang, XL Zhou, W Yan, G Eriani, ED Wang Nucleic acids research 41 (10), 5513-5523, 2013 | 14 | 2013 |
Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia Y Hu, L Liu, Y Chen, X Zhang, H Zhou, S Hu, X Li, M Li, J Li, S Cheng, ... Nature Communications 14 (1), 5179, 2023 | 13 | 2023 |
Leucine-specific domain modulates the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase W Yan, M Tan, G Eriani, ED Wang Nucleic acids research 41 (9), 4988-4998, 2013 | 13 | 2013 |
Extracellular vesicle-mediated interorgan communication in metabolic diseases S Hu, Y Hu, W Yan Trends in Endocrinology & Metabolism, 2023 | 10 | 2023 |
Modulation of aminoacylation and editing properties of leucyl-tRNA synthetase by a conserved structural module W Yan, Q Ye, M Tan, X Chen, G Eriani, ED Wang Journal of Biological Chemistry 290 (19), 12256-12267, 2015 | 9 | 2015 |
The biological function of tumor-derived extracellular vesicles on metabolism X Fu, J Song, W Yan, BM Downs, W Wang, J Li Cell Communication and Signaling 21 (1), 150, 2023 | 8 | 2023 |