Structural rearrangement in an RsmA/CsrA ortholog of Pseudomonas aeruginosa creates a dimeric RNA-binding protein, RsmN ER Morris, G Hall, C Li, S Heeb, RV Kulkarni, L Lovelock, H Silistre, ... Structure 21 (9), 1659-1671, 2013 | 92 | 2013 |
Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI C Li, KM Voos, M Pathak, G Hall, KR McCrae, I Dreveny, R Li, J Emsley Journal of Thrombosis and Haemostasis 17 (5), 759-770, 2019 | 30 | 2019 |
Allosteric activation of MALT1 by its ubiquitin-binding Ig3 domain R Schairer, G Hall, M Zhang, R Cowan, R Baravalle, FW Muskett, ... Proceedings of the National Academy of Sciences 117 (6), 3093-3102, 2020 | 23 | 2020 |
A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain SS Wong, S Østergaard, G Hall, C Li, PM Williams, H Stennicke, J Emsley Blood, The Journal of the American Society of Hematology 127 (23), 2915-2923, 2016 | 23 | 2016 |
Discovery of a novel pseudo β-hairpin structure of N-truncated amyloid-β for use as a vaccine against Alzheimer’s disease P Bakrania, G Hall, Y Bouter, C Bouter, N Beindorff, R Cowan, S Davies, ... Molecular Psychiatry 27 (2), 840-848, 2022 | 22 | 2022 |
Structure of human thioredoxin exhibits a large conformational change G Hall, J Emsley Protein Science 19 (9), 1807-1811, 2010 | 22 | 2010 |
Structure of Mycobacterium tuberculosis thioredoxin C G Hall, M Shah, PA McEwan, C Laughton, M Stevens, A Westwell, ... Acta Crystallographica Section D: Biological Crystallography 62 (12), 1453-1457, 2006 | 22 | 2006 |
Cross-reactive SARS-CoV-2 neutralizing antibodies from deep mining of early patient responses G Bullen, JD Galson, G Hall, P Villar, L Moreels, L Ledsgaard, G Mattiuzzo, ... Frontiers in Immunology 12, 678570, 2021 | 20 | 2021 |
Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464 G Hall, TD Bradshaw, CA Laughton, MF Stevens, J Emsley Protein science 20 (1), 210-215, 2011 | 16 | 2011 |
Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16) G Hall, E Cullen, K Sawmynaden, J Arnold, S Fox, R Cowan, FW Muskett, ... Journal of Biological Chemistry 291 (32), 16840-16848, 2016 | 15 | 2016 |
Nanostructures from Self‐Assembling Triazine Tertiary Amine N‐Oxide Amphiphiles MP Beecham, GJ Clarkson, G Hall, A Marsh ChemPhysChem 14 (17), 3909-3915, 2013 | 5 | 2013 |
Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80 T Kang-Pettinger, K Walker, R Brown, R Cowan, H Wright, R Baravalle, ... Journal of Biological Chemistry 299 (1), 2023 | 4 | 2023 |
Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence G Bullen, JD Galson, P Villar, L Moreels, L Ledsgaard, G Mattiuzzo, G Hall, ... bioRxiv, 2020.12. 29.424711, 2020 | 3 | 2020 |
Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors AJ Wilkinson, N Ooi, J Finlayson, VE Lee, D Lyth, KS Maskew, R Newman, ... Bioorganic & Medicinal Chemistry Letters 90, 129331, 2023 | 1 | 2023 |
Nanobody inhibitors of Plexin-B1 identify allostery in plexin–semaphorin interactions and signaling R Cowan, M Trokter, A Oleksy, M Fedorova, K Sawmynaden, T Worzfeld, ... Journal of Biological Chemistry 299 (6), 2023 | 1 | 2023 |
A novel SS Wong, S Østergaard, G Hall, C Li, PM Williams, H Stennicke, J Emsley | 1 | 2016 |
Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool K Sawmynaden, N Wong, S Davies, R Cowan, R Brown, D Tang, M Henry, ... Plos one 18 (7), e0288259, 2023 | | 2023 |
Cyclic Peptides P Bakrania, D Matthews, L Elizabeth, C Mpamhanga, T Bayer, M Carr, ... US Patent App. 17/905,894, 2023 | | 2023 |
Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug … MD Carr, K Walker, R Baravalle, R Holyfield, J Kalms, H Wright, ... Frontiers in Immunology 14, 1216967, 2023 | | 2023 |
Humanised anti-n-truncated amyloid beta monoclonal antibody T Bayer, P Bakrania, S Davies, A Brown, C Mpamhanga, D Matthews, ... | | 2021 |