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Eugene Khandros
Eugene Khandros
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
在 chop.edu 的电子邮件经过验证
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引用次数
引用次数
年份
Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability
Y Kirino, N Kim, M de Planell-Saguer, E Khandros, S Chiorean, PS Klein, ...
Nature cell biology 11 (5), 652-658, 2009
2832009
miR-451 protects against erythroid oxidant stress by repressing 14-3-3ζ
D Yu, CO dos Santos, G Zhao, J Jiang, JD Amigo, E Khandros, LC Dore, ...
Genes & development 24 (15), 1620-1633, 2010
2512010
Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate
ST Chou, E Khandros, LC Bailey, KE Nichols, CR Vakoc, Y Yao, Z Huang, ...
Blood, The Journal of the American Society of Hematology 114 (5), 983-994, 2009
1582009
Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia
E Khandros, CS Thom, J D'Souza, MJ Weiss
Blood, The Journal of the American Society of Hematology 119 (22), 5265-5275, 2012
1062012
A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex
SV Puthanveettil, FJ Monje, MC Miniaci, YB Choi, KA Karl, E Khandros, ...
Cell 135 (5), 960-973, 2008
1042008
Trim58 degrades Dynein and regulates terminal erythropoiesis
CS Thom, EA Traxler, E Khandros, JM Nickas, OY Zhou, JE Lazarus, ...
Developmental cell 30 (6), 688-700, 2014
962014
Beta thalassemia: monitoring and new treatment approaches
E Khandros, JL Kwiatkowski
Hematology/Oncology Clinics 33 (3), 339-353, 2019
612019
Protein quality control during erythropoiesis and hemoglobin synthesis
E Khandros, MJ Weiss
Hematology/Oncology Clinics 24 (6), 1071-1088, 2010
592010
The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression
P Huang, SA Peslak, X Lan, E Khandros, JA Yano, M Sharma, CA Keller, ...
Blood, The Journal of the American Society of Hematology 135 (24), 2121-2132, 2020
542020
The autophagy-activating kinase ULK1 mediates clearance of free α-globin in β-thalassemia
C Lechauve, J Keith, E Khandros, S Fowler, K Mayberry, A Freiwan, ...
Science translational medicine 11 (506), eaav4881, 2019
532019
The Spectrum of SPTA1-Associated Hereditary Spherocytosis
S Chonat, M Risinger, H Sakthivel, O Niss, JA Rothman, L Hsieh, ...
Frontiers in physiology 10, 815, 2019
462019
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
Z Cao, KA Budinich, H Huang, D Ren, B Lu, Z Zhang, Q Chen, Y Zhou, ...
Molecular cell 81 (17), 3604-3622. e10, 2021
412021
The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis
Z Zou, DR Enis, H Bui, E Khandros, V Kumar, Z Jakus, C Thom, Y Yang, ...
Blood, The Journal of the American Society of Hematology 121 (16), 3228-3236, 2013
392013
Kinetics of α-globin binding to α-hemoglobin stabilizing protein (AHSP) indicate preferential stabilization of hemichrome folding intermediate
TL Mollan, E Khandros, MJ Weiss, JS Olson
Journal of Biological Chemistry 287 (14), 11338-11350, 2012
342012
The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells
X Lan, E Khandros, P Huang, SA Peslak, SK Bhardwaj, JD Grevet, ...
Blood Advances 3 (10), 1586-1597, 2019
332019
Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts
E Khandros, P Huang, SA Peslak, M Sharma, O Abdulmalik, BM Giardine, ...
Blood, The Journal of the American Society of Hematology 135 (22), 1957-1968, 2020
322020
Insights into hemoglobin assembly through in vivo mutagenesis of α-hemoglobin stabilizing protein
E Khandros, TL Mollan, X Yu, X Wang, Y Yao, J D'Souza, DA Gell, ...
Journal of Biological Chemistry 287 (14), 11325-11337, 2012
282012
Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia
M Nasimuzzaman, E Khandros, X Wang, Y Kong, H Zhao, D Weiss, ...
American journal of hematology 85 (10), 820, 2010
252010
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription
P Huang, SA Peslak, R Ren, E Khandros, K Qin, CA Keller, B Giardine, ...
Nature genetics 54 (9), 1417-1426, 2022
242022
Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells
K Qin, P Huang, R Feng, CA Keller, SA Peslak, E Khandros, MS Saari, ...
Nature genetics 54 (6), 874-884, 2022
242022
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