Human DNA-PK activates a STING-independent DNA sensing pathway K Burleigh, JH Maltbaek, S Cambier, R Green, M Gale Jr, RC James, ... Science immunology 5 (43), eaba4219, 2020 | 169 | 2020 |
PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal TumorsPD-1/PD-L1 in GISTs AM Seifert, S Zeng, JQ Zhang, TS Kim, NA Cohen, MJ Beckman, ... Clinical Cancer Research 23 (2), 454-465, 2017 | 149 | 2017 |
ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP JH Maltbaek, S Cambier, JM Snyder, DB Stetson Immunity 55 (10), 1799-1812. e4, 2022 | 73 | 2022 |
Macrophages and CD8+ T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal TumorsCD40 Activation in GIST JQ Zhang, S Zeng, GA Vitiello, AM Seifert, BD Medina, MJ Beckman, ... Cancer immunology research 6 (4), 434-447, 2018 | 68* | 2018 |
Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal TumorWnt/β-catenin in GIST S Zeng, AM Seifert, JQ Zhang, MJ Cavnar, TS Kim, VP Balachandran, ... Molecular cancer therapeutics 16 (9), 1954-1966, 2017 | 48 | 2017 |
Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity BD Medina, M Liu, GA Vitiello, AM Seifert, S Zeng, T Bowler, JQ Zhang, ... Journal of Experimental Medicine 216 (6), 1359-1376, 2019 | 28 | 2019 |
Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells JA Santamaria-Barria, S Zeng, JB Greer, MJ Beckman, AM Seifert, ... PloS one 14 (5), e0216275, 2019 | 19 | 2019 |
The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor JQ Zhang, B Bosbach, JK Loo, GA Vitiello, S Zeng, AM Seifert, BD Medina, ... Oncogene 39 (49), 7153-7165, 2020 | 12 | 2020 |
Follicular lymphoma-protective HLA class II variants correlate with increased HLA-DQB1 protein expression FCM Sillé, L Conde, J Zhang, NK Akers, S Sanchez, J Maltbaek, JE Riby, ... Genes & Immunity 15 (2), 133-136, 2014 | 11 | 2014 |
ABCC1/MRP1 exports cGAMP and modulates cGAS-dependent immunity JH Maltbaek, JM Snyder, DB Stetson bioRxiv, 2021 | 3 | 2021 |
Methods for treating autoimmune or autoinflammatory disease DB Stetson, K Burleigh, J Maltbaek US Patent App. 17/435,194, 2022 | | 2022 |
Discovery of a Novel cGAMP Exporter that Regulates Innate Antiviral Immunity J Maltbaek University of Washington, 2022 | | 2022 |