PKA/AKAP/VR-1 module: A common link of Gs-mediated signaling to thermal hyperalgesia PK Rathee, C Distler, O Obreja, W Neuhuber, GK Wang, SY Wang, C Nau, ... Journal of Neuroscience 22 (11), 4740-4745, 2002 | 309 | 2002 |
IL‐1J potentiates heat‐activated currents in rat sensory neurons: involvement of IL‐1RI, tyrosine kinase, and protein kinase C O Obreja, PK Rathee, KS Lips, C Distler, M Kress The FASEB journal 16 (12), 1497-1503, 2002 | 301 | 2002 |
NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin R Rukwied, A Mayer, O Kluschina, O Obreja, M Schley, M Schmelz Pain 148 (3), 407-413, 2010 | 185 | 2010 |
Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo O Obreja, M Schmelz, S Poole, M Kress Pain 96 (1-2), 57-62, 2002 | 171 | 2002 |
Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons O Obreja, W Biasio, M Andratsch, KS Lips, PK Rathee, A Ludwig, ... Brain 128 (7), 1634-1641, 2005 | 157 | 2005 |
The inflammatory mediators serotonin, prostaglandin E2 and bradykinin evoke calcium influx in rat sensory neurons O Linhart, O Obreja, M Kress Neuroscience 118 (1), 69-74, 2003 | 117 | 2003 |
NGF-evoked sensitization of muscle fascia nociceptors in humans S Deising, B Weinkauf, J Blunk, O Obreja, M Schmelz, R Rukwied PAIN® 153 (8), 1673-1679, 2012 | 113 | 2012 |
Modeling activity-dependent changes of axonal spike conduction in primary afferent C-nociceptors J Tigerholm, ME Petersson, O Obreja, A Lampert, R Carr, M Schmelz, ... Journal of neurophysiology 111 (9), 1721-1735, 2014 | 93 | 2014 |
Nerve growth factor induces sensitization of nociceptors without evidence for increased intraepidermal nerve fiber density M Hirth, R Rukwied, A Gromann, B Turnquist, B Weinkauf, K Francke, ... PAIN® 154 (11), 2500-2511, 2013 | 74 | 2013 |
Potentiation of nociceptive responses to low pH injections in humans by prostaglandin E2 R Rukwied, BA Chizh, U Lorenz, O Obreja, S Margarit, M Schley, ... The Journal of Pain 8 (5), 443-451, 2007 | 73 | 2007 |
Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human O Obreja, M Ringkamp, B Namer, E Forsch, A Klusch, R Rukwied, ... Pain 148 (1), 59-69, 2010 | 70 | 2010 |
Cryptococcal meningoencephalitis in a patient with multiple sclerosis treated with fingolimod L Achtnichts, O Obreja, A Conen, CA Fux, K Nedeltchev Jama Neurology 72 (10), 1203-1205, 2015 | 62 | 2015 |
Fast Ca2+-Induced Potentiation of Heat-Activated Ionic Currents Requires cAMP/PKA Signaling and Functional AKAP Anchoring C Distler, PK Rathee, KS Lips, O Obreja, W Neuhuber, M Kress Journal of neurophysiology 89 (5), 2499-2505, 2003 | 52 | 2003 |
Nerve growth factor locally sensitizes nociceptors in human skin O Obreja, R Rukwied, L Nagler, M Schmidt, M Schmelz, B Namer Pain 159 (3), 416-426, 2018 | 47 | 2018 |
Nerve growth factor selectively decreases activity-dependent conduction slowing in mechano-insensitive C-nociceptors O Obreja, M Ringkamp, B Turnquist, M Hirth, E Forsch, R Rukwied, ... Pain 152 (9), 2138-2146, 2011 | 41 | 2011 |
NGF enhances electrically induced pain, but not axon reflex sweating O Obreja, O Kluschina, A Mayer, M Hirth, M Schley, M Schmelz, ... Pain 152 (8), 1856-1863, 2011 | 37 | 2011 |
Neurogenic components of trypsin‐ and thrombin‐induced inflammation in rat skin, in vivo O Obreja, R Rukwied, M Steinhoff, M Schmelz Experimental dermatology 15 (1), 58-65, 2006 | 35 | 2006 |
Double spikes to single electrical stimulation correlates to spontaneous activity of nociceptors in painful neuropathy patients R Schmidt, IP Kleggetveit, B Namer, T Helås, O Obreja, M Schmelz, ... Pain 153 (2), 391-398, 2012 | 33 | 2012 |
Comparison of nerve growth factor–induced sensitization pattern in lumbar and tibial muscle and fascia B Weinkauf, S Deising, O Obreja, U Hoheisel, S Mense, M Schmelz, ... Muscle & nerve 52 (2), 265-272, 2015 | 30 | 2015 |
Differential axonal conduction patterns of mechano-sensitive and mechano-insensitive nociceptors–a combined experimental and modelling study ME Petersson, O Obreja, A Lampert, RW Carr, M Schmelz, E Fransén PLoS One 9 (8), e103556, 2014 | 29 | 2014 |