| Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells H Liu, RC Bowes, B van de Water, C Sillence, JF Nagelkerke, JL Stevens Journal of Biological Chemistry 272 (35), 21751-21759, 1997 | 461 | 1997 |
| E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines M Lombaerts, T Van Wezel, K Philippo, JWF Dierssen, RME Zimmerman, ... British journal of cancer 94 (5), 661-671, 2006 | 449 | 2006 |
| A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies SC Ramaiahgari, MW Den Braver, B Herpers, V Terpstra, ... Archives of toxicology 88, 1083-1095, 2014 | 436 | 2014 |
| Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain M Kruidering, B Van De Water, E De Heer, GJ Mulder, JF Nagelkerke Journal of Pharmacology and Experimental Therapeutics 280 (2), 638-649, 1997 | 403 | 1997 |
| Focal adhesion kinase: a potential target in cancer therapy MJ van Nimwegen, B van de Water Biochemical pharmacology 73 (5), 597-609, 2007 | 376 | 2007 |
| Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 334 | 2017 |
| Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death H Liu, E Miller, B van de Water, JL Stevens Journal of Biological Chemistry 273 (21), 12858-12862, 1998 | 259 | 1998 |
| Current EU research activities on combined exposure to multiple chemicals SK Bopp, R Barouki, W Brack, S Dalla Costa, JLCM Dorne, PE Drakvik, ... Environment international 120, 544-562, 2018 | 236 | 2018 |
| Annexin A1 regulates TGF-β signaling and promotes metastasis formation of basal-like breast cancer cells M de Graauw, MH van Miltenburg, MK Schmidt, C Pont, R Lalai, ... Proceedings of the National Academy of Sciences 107 (14), 6340-6345, 2010 | 223 | 2010 |
| Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development U Marx, T Akabane, TB Andersson, E Baker, M Beilmann, S Beken, ... Altex 37 (3), 365, 2020 | 222 | 2020 |
| Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment E Drakvik, R Altenburger, Y Aoki, T Backhaus, T Bahadori, R Barouki, ... Environment international 134, 105267, 2020 | 210 | 2020 |
| Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes Y Zhang, M Moerkens, S Ramaiahgari, H de Bont, L Price, J Meerman, ... Breast cancer research 13, 1-16, 2011 | 209 | 2011 |
| Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE* 3-Leiden transgenic mice BJM van Vlijmen, G Gerritsen, AL Franken, LSM Boesten, MM Kockx, ... Circulation research 88 (8), 780-786, 2001 | 199 | 2001 |
| The membrane attack complex of complement induces caspase activation and apoptosis AJ Nauta, MR Daha, O Tijsma, B van de Water, F Tedesco, A Roos European journal of immunology 32 (3), 783-792, 2002 | 182 | 2002 |
| Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models RJ Weaver, EA Blomme, AE Chadwick, IM Copple, HHJ Gerets, ... Nature Reviews Drug Discovery 19 (2), 131-148, 2020 | 179 | 2020 |
| Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling … H Happé, WN Leonhard, A van der Wal, B van de Water, ... Human molecular genetics 18 (14), 2532-2542, 2009 | 177 | 2009 |
| Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation MJ van Nimwegen, S Verkoeijen, L van Buren, D Burg, B van de Water Cancer Research 65 (11), 4698-4706, 2005 | 167 | 2005 |
| A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration K Yizhak, SE Le Dévédec, VM Rogkoti, F Baenke, VC De Boer, C Frezza, ... Molecular systems biology 10 (8), 744, 2014 | 163 | 2014 |
| Toxicogenomics directory of chemically exposed human hepatocytes M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ... Archives of toxicology 88, 2261-2287, 2014 | 150 | 2014 |
| Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance JG Van Oosterwijk, B Herpers, D Meijer, IH Briaire-de Bruijn, ... Annals of oncology 23 (6), 1617-1626, 2012 | 147 | 2012 |
Judith BoveeProfessor of Pathology, LUMC在 lumc.nl 的电子邮件经过验证
Judith BoveeProfessor of Pathology, LUMC在 lumc.nl 的电子邮件经过验证