SGLT2 mediates glucose reabsorption in the early proximal tubule V Vallon, KA Platt, R Cunard, J Schroth, J Whaley, SC Thomson, ... Journal of the American Society of Nephrology 22 (1), 104-112, 2011 | 586 | 2011 |
Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition V Vallon, SC Thomson Diabetologia 60 (2), 215-225, 2017 | 560 | 2017 |
SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice V Vallon, M Gerasimova, MA Rose, T Masuda, J Satriano, E Mayoux, ... American Journal of Physiology-Renal Physiology 306 (2), F194-F204, 2014 | 521 | 2014 |
Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption V Vallon, K Richter, RC Blantz, S Thomson, H Osswald Journal of the American Society of Nephrology 10 (12), 2569-2576, 1999 | 439 | 1999 |
Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney V Vallon, SC Thomson Annual review of physiology 74, 351-375, 2012 | 420 | 2012 |
Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus V Vallon, M Rose, M Gerasimova, J Satriano, KA Platt, H Koepsell, ... American Journal of Physiology-Renal Physiology 304 (2), F156-F167, 2013 | 405 | 2013 |
Kidney function in early diabetes: the tubular hypothesis of glomerular filtration SC Thomson, V Vallon, RC Blantz American Journal of Physiology-Renal Physiology 286 (1), F8-F15, 2004 | 312 | 2004 |
Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia T Rieg, T Masuda, M Gerasimova, E Mayoux, K Platt, DR Powell, ... American Journal of Physiology-Renal Physiology 306 (2), F188-F193, 2014 | 307 | 2014 |
Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat SC Thomson, T Rieg, C Miracle, H Mansoury, J Whaley, V Vallon, P Singh American Journal of Physiology-Regulatory, Integrative and Comparative …, 2012 | 302 | 2012 |
The tubular hypothesis of nephron filtration and diabetic kidney disease V Vallon, SC Thomson Nature Reviews Nephrology 16 (6), 317-336, 2020 | 294 | 2020 |
Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes SC Thomson, A Deng, D Bao, J Satriano, RC Blantz, V Vallon The Journal of clinical investigation 107 (2), 217-224, 2001 | 273 | 2001 |
Agmatine, a bioactive metabolite of arginine. Production, degradation, and functional effects in the kidney of the rat. MJ Lortie, WF Novotny, OW Peterson, V Vallon, K Malvey, M Mendonca, ... The Journal of clinical investigation 97 (2), 413-420, 1996 | 216 | 1996 |
Glomerular hyperfiltration and the salt paradox in early type 1 diabetes mellitus: a tubulo-centric view V Vallon, RC Blantz, S Thomson Journal of the American Society of Nephrology 14 (2), 530-537, 2003 | 214 | 2003 |
Adenosine formed by 5′-nucleotidase mediates tubuloglomerular feedback S Thomson, D Bao, A Deng, V Vallon The Journal of clinical investigation 106 (2), 289-298, 2000 | 203 | 2000 |
Arginine feeding modifies cyclosporine nephrotoxicity in rats. L De Nicola, SC Thomson, LM Wead, MR Brown, FB Gabbai The Journal of clinical investigation 92 (4), 1859-1865, 1993 | 150 | 1993 |
A role for tubular Na+/H+ exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin A Onishi, Y Fu, R Patel, M Darshi, M Crespo-Masip, W Huang, P Song, ... American Journal of Physiology-Renal Physiology 319 (4), F712-F728, 2020 | 145 | 2020 |
Glomerulotubular balance, tubuloglomerular feedback, and salt homeostasis SC Thomson, RC Blantz Journal of the American Society of Nephrology 19 (12), 2272-2275, 2008 | 134 | 2008 |
Homeostatic efficiency of tubuloglomerular feedback is reduced in established diabetes mellitus in rats V Vallon, RC Blantz, S Thomson American Journal of Physiology-Renal Physiology 269 (6), F876-F883, 1995 | 129 | 1995 |
Suppression of inducible nitric oxide generation by agmatine aldehyde: beneficial effects in sepsis J Satriano, D Schwartz, S Ishizuka, MJ Lortie, SC Thomson, F Gabbai, ... Journal of cellular physiology 188 (3), 313-320, 2001 | 113 | 2001 |
The effect of KW-3902, an adenosine A1 receptor antagonist, on renal function and renal plasma flow in ambulatory patients with heart failure and renal impairment HC Dittrich, DK Gupta, TC Hack, T Dowling, J Callahan, S Thomson Journal of cardiac failure 13 (8), 609-617, 2007 | 109 | 2007 |