Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia A El-Osta, D Brasacchio, D Yao, A Pocai, PL Jones, RG Roeder, ... The Journal of experimental medicine 205 (10), 2409-2417, 2008 | 1264 | 2008 |
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail D Brasacchio, J Okabe, C Tikellis, A Balcerczyk, P George, EK Baker, ... Diabetes 58 (5), 1229-1236, 2009 | 596 | 2009 |
Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing H KN, MZ Chow, EK Baker, S Pal, S Bassal, D Brasacchio, L Wang, ... Nature genetics 37 (3), 254-264, 2005 | 389 | 2005 |
Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase A Soro-Paavonen, WZ Zhang, K Venardos, MT Coughlan, E Harris, ... Journal of hypertension 28 (4), 780-788, 2010 | 120 | 2010 |
Controversies in granzyme biology O Susanto, JA Trapani, D Brasacchio Tissue antigens 80 (6), 477-487, 2012 | 88 | 2012 |
Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice AMD Watson, A Soro-Paavonen, K Sheehy, J Li, AC Calkin, A Koitka, ... Diabetologia 54, 681-689, 2011 | 87 | 2011 |
Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis O Susanto, SE Stewart, I Voskoboinik, D Brasacchio, M Hagn, S Ellis, ... Cell Death & Differentiation 20 (9), 1183-1193, 2013 | 72 | 2013 |
Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization D Brasacchio, AE Alsop, T Noori, M Lufti, S Iyer, KJ Simpson, PI Bird, ... Cell Death & Differentiation 24 (6), 961-970, 2017 | 53 | 2017 |
A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage D Brasacchio, T Noori, C House, AJ Brennan, KJ Simpson, O Susanto, ... Cell Death & Differentiation 21 (5), 748-760, 2014 | 22 | 2014 |
Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer D Brasacchio, RA Busuttil, T Noori, RW Johnstone, A Boussioutas, ... Cell death & disease 9 (5), 442, 2018 | 21 | 2018 |
Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma J Wong, E Gruber, B Maher, M Waltham, Z Sabouri-Thompson, I Jong, ... Leukemia 36 (6), 1654-1665, 2022 | 14 | 2022 |
Molecular associations of response to the new-generation BTK inhibitor zanubrutinib in marginal zone lymphoma M Tatarczuch, M Waltham, J Shortt, G Polekhina, EA Hawkes, SJ Ho, ... Blood Advances 7 (14), 3531-3539, 2023 | 7 | 2023 |
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma DH Oh, X Ma, SJ Hogg, J He, C Kearney, D Brasacchio, O Susanto, ... Proceedings of the National Academy of Sciences 120 (36), e2306414120, 2023 | 2 | 2023 |
Experiences of Caregivers and At-Risk Children Enrolled in a Prospective Pregnancy-Birth Cohort Study into the Causes of Type 1 Diabetes: The ENDIA Study KJ McGorm, JD Brown, AG Roberts, S Greenbank, D Brasacchio, ... Children 10 (4), 637, 2023 | 1 | 2023 |
P1212: RATIONALLY DESIGNED CHIMERIC PI3K-BET BROMODOMAIN INHIBITORS ELICIT CURATIVE RESPONSES IN MYC-DRIVEN LYMPHOMA DH Oh, MA Xiao, J He, C Kearney, SJ Hogg, A Newbold, P Fraser, ... HemaSphere 7 (S3), e4369469, 2023 | | 2023 |
P1261: ALLG LABORATORY SCIENCE STUDY LS21: MOLECULAR CORRELATES OF RESPONSE IN RELAPSED/REFRACTORY MARGINAL ZONE LYMPHOMA (RRMZL) PATIENTS TREATED WITH ZANUBRUTINIB IN THE … M Tatarczuch, M Waltham, J Shortt, E Hawkes, SJ Ho, J Trotman, ... HemaSphere 6, 1146-1147, 2022 | | 2022 |
Australasian Leukaemia and Lymphoma Group (ALLG) Laboratory Science Study LS21: Molecular Correlates of Response in Relapsed/Refractory Marginal Zone Lymphoma (rrMZL) Patients … M Tatarczuch, MC Waltham, J Shortt, G Polekhina, EA Hawkes, SJ Ho, ... Blood 2022, 2022 | | 2022 |
ALLG Laboratory Science Study LS21: Molecular Correlates of Response in Relapsed/Refractory Marginal Zone Lymphoma Patients Treated with Zanubrutinib in the MAGNOLIA Trial M Tatarczuch, MC Waltham, J Shortt, EA Hawkes, SJ Ho, J Trotman, ... European Hematology Association Congress 2022, 2022 | | 2022 |
Bappaya, S. Tuesday 09 August–Short Presentation–Session 3/0820–0830 Bar, I. 220 R Barba-Pichardo, XH Ang, R Anscombe, S Anwar, T Ariyaratne, ... Heart, Lung and Circulation 20, e1-e10, 2011 | | 2011 |
Validation of Current Valve-specific Risk Models in the Australian Population T Ariyaratne, CH Yap, B Billah, D Brasacchio, D Dinh, J Smith Heart, Lung and Circulation 20 (1), 55, 2011 | | 2011 |