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Di Hu
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引用次数
年份
VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease
X Guo, XY Sun, D Hu, YJ Wang, H Fujioka, R Vyas, S Chakrapani, ...
Nature communications 7 (1), 12646, 2016
1672016
Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer’s disease
X Zhang, R Wang, D Hu, X Sun, H Fujioka, K Lundberg, ER Chan, ...
Science advances 6 (49), eabb8680, 2020
972020
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity
D Hu, X Sun, X Liao, X Zhang, S Zarabi, A Schimmer, Y Hong, C Ford, ...
Acta neuropathologica 137, 939-960, 2019
752019
ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects
Y Zhao, X Sun, D Hu, DA Prosdocimo, C Hoppel, MK Jain, ...
Nature communications 10 (1), 1371, 2019
742019
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer’s disease models
Y Zhao, D Hu, R Wang, X Sun, P Ropelewski, Z Hubler, K Lundberg, ...
Nature communications 13 (1), 1121, 2022
382022
Using induced pluripotent stem cell neuronal models to study neurodegenerative diseases
X Zhang, D Hu, Y Shang, X Qi
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (4), 165431, 2020
322020
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington’s disease
D Hu, X Sun, A Magpusao, Y Fedorov, M Thompson, B Wang, K Lundberg, ...
Nature communications 12 (1), 5305, 2021
242021
Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
R Jobava, Y Mao, BJ Guan, D Hu, D Krokowski, CW Chen, XE Shu, ...
Molecular Cell 81 (20), 4191-4208. e8, 2021
212021
Mitochondrial quality control strategies: potential therapeutic targets for neurodegenerative diseases?
D Hu, Z Liu, X Qi
Frontiers in Neuroscience 15, 746873, 2021
192021
UPRmt activation protects against MPP+-induced toxicity in a cell culture model of Parkinson's disease
D Hu, Z Liu, X Qi
Biochemical and biophysical research communications 569, 17-22, 2021
142021
Integrin β3-mediated cell senescence associates with gut inflammation and intestinal degeneration in models of Alzheimer’s disease
X Tun, EJ Wang, Z Gao, K Lundberg, R Xu, D Hu
International Journal of Molecular Sciences 24 (6), 5697, 2023
62023
AI is a viable alternative to high throughput screening: a 318-target study
Scientific reports 14 (1), 7526, 2024
32024
Measuring Drp1 activity in mitochondrial fission in vivo
D Hu, X Qi
Dynamin Superfamily GTPases: Methods and Protocols, 189-195, 2020
32020
Quantifying Drp1-Mediated Mitochondrial Fission by Immunostaining in Fixed Cells
D Hu, X Qi
Dynamin Superfamily GTPases: Methods and Protocols, 197-204, 2020
22020
Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif
I Pérez-Jover, K Rochon, D Hu, M Mahajan, P Madan Mohan, ...
Nature Communications 15 (1), 52, 2024
12024
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