Cysteine redox sensor in PKGIa enables oxidant-induced activation JR Burgoyne, M Madhani, F Cuello, RL Charles, JP Brennan, ... Science 317 (5843), 1393-1397, 2007 | 522 | 2007 |
Disruption of methylarginine metabolism impairs vascular homeostasis J Leiper, M Nandi, B Torondel, J Murray-Rust, M Malaki, B O'Hara, ... Nature medicine 13 (2), 198-203, 2007 | 478 | 2007 |
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the … RS Scotland, M Madhani, S Chauhan, S Moncada, J Andresen, H Nilsson, ... Circulation 111 (6), 796-803, 2005 | 280 | 2005 |
Resistance to Endotoxic Shock in Endothelial Nitric-oxide Synthase (eNOS) Knock-out Mice: A PRO-INFLAMMATORY ROLE FOR eNOS-DERIVED NO IN VIVO*♦ L Connelly, M Madhani, AJ Hobbs Journal of Biological Chemistry 280 (11), 10040-10046, 2005 | 193 | 2005 |
Endothelial dysfunction and cardiovascular disease in early-stage chronic kidney disease: cause or association? WE Moody, NC Edwards, M Madhani, CD Chue, RP Steeds, CJ Ferro, ... Atherosclerosis 223 (1), 86-94, 2012 | 176 | 2012 |
Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI) N Siddiqi, C Neil, M Bruce, G MacLennan, S Cotton, S Papadopoulou, ... European heart journal 35 (19), 1255-1262, 2014 | 173 | 2014 |
Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor IC Villar, CM Panayiotou, A Sheraz, M Madhani, RS Scotland, M Nobles, ... Cardiovascular research 74 (3), 515-525, 2007 | 125 | 2007 |
Vascular natriuretic peptide receptor‐linked particulate guanylate cyclases are modulated by nitric oxide–cyclic GMP signalling M Madhani, RS Scotland, RJ MacAllister, AJ Hobbs British journal of pharmacology 139 (7), 1289-1296, 2003 | 95 | 2003 |
Cardiac metabolism—a promising therapeutic target for heart failure H Noordali, BL Loudon, MP Frenneaux, M Madhani Pharmacology & therapeutics 182, 95-114, 2018 | 82 | 2018 |
Synergy between natriuretic peptides and phosphodiesterase 5 inhibitors ameliorates pulmonary arterial hypertension RS Baliga, L Zhao, M Madhani, B Lopez-Torondel, C Visintin, D Selwood, ... American journal of respiratory and critical care medicine 178 (8), 861-869, 2008 | 76 | 2008 |
Pharmacology and therapeutic role of inorganic nitrite and nitrate in vasodilatation JC Bailey, M Feelisch, JD Horowitz, MP Frenneaux, M Madhani Pharmacology & therapeutics 144 (3), 303-320, 2014 | 69 | 2014 |
A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome TR Sutton, M Minnion, F Barbarino, G Koster, BO Fernandez, ... Redox biology 16, 359-380, 2018 | 68 | 2018 |
Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury M Madhani, AR Hall, F Cuello, RL Charles, JR Burgoyne, W Fuller, ... American Journal of Physiology-Heart and Circulatory Physiology 299 (3 …, 2010 | 57 | 2010 |
Biological activity of designed photolabile metal nitrosyls: light-dependent activation of soluble guanylate cyclase and vasorelaxant properties in rat aorta M Madhani, AK Patra, TW Miller, AA Eroy-Reveles, AJ Hobbs, JM Fukuto, ... Journal of medicinal chemistry 49 (25), 7325-7330, 2006 | 54 | 2006 |
Endotoxin-induced liver hypoxia: defective oxygen delivery versus oxygen consumption PE James, M Madhani, W Roebuck, SK Jackson, HM Swartz Nitric Oxide 6 (1), 18-28, 2002 | 54 | 2002 |
Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling M Feelisch, T Akaike, K Griffiths, T Ida, O Prysyazhna, JJ Goodwin, ... Cardiovascular Research 116 (1), 51-62, 2020 | 45 | 2020 |
Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo M Madhani, M Okorie, AJ Hobbs, RJ MacAllister British journal of pharmacology 149 (6), 797-801, 2006 | 43 | 2006 |
Short-term intravenous sodium nitrite infusion improves cardiac and pulmonary hemodynamics in heart failure patients JOM Ormerod, S Arif, M Mukadam, JDW Evans, R Beadle, BO Fernandez, ... Circulation: Heart Failure 8 (3), 565-571, 2015 | 40 | 2015 |
In vivo EPR spectroscopy: biomedical and potential diagnostic applications SK Jackson, MP Thomas, S Smith, M Madhani, SC Rogers, PE James Faraday Discussions 126, 103-117, 2004 | 38 | 2004 |
The cardioprotective effects of secretory leukocyte protease inhibitor against myocardial ischemia/reperfusion injury E Prompunt, J Sanit, S Barrère‑Lemaire, J Nargeot, H Noordali, ... Experimental and therapeutic medicine 15 (6), 5231-5242, 2018 | 34 | 2018 |