关注
Nessim Kichik
Nessim Kichik
King's College London / Imperial College London
在 kcl.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Candidalysin is a fungal peptide toxin critical for mucosal infection
DL Moyes, D Wilson, JP Richardson, S Mogavero, SX Tang, J Wernecke, ...
Nature 532 (7597), 64-68, 2016
8142016
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor
J Ho, X Yang, SA Nikou, N Kichik, A Donkin, NO Ponde, JP Richardson, ...
Nature communications 10 (1), 2297, 2019
1332019
Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor
T Tarragó, N Kichik, B Claasen, R Prades, M Teixidó, E Giralt
Bioorganic & medicinal chemistry 16 (15), 7516-7524, 2008
1332008
The natural product berberine is a human prolyl oligopeptidase inhibitor
T Tarrago, N Kichik, J Seguí, E Giralt
ChemMedChem: Chemistry Enabling Drug Discovery 2 (3), 354-359, 2007
932007
Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence
JP Richardson, S Mogavero, DL Moyes, M Blagojevic, T Krüger, ...
MBio 9 (1), 10.1128/mbio. 02178-17, 2018
842018
Candida albicans Interactions with Mucosal Surfaces during Health and Disease
SA Nikou, N Kichik, R Brown, NO Ponde, J Ho, JR Naglik, JP Richardson
Pathogens 8 (2), 53, 2019
812019
Candida albicans and candidalysin in inflammatory disorders and cancer
J Ho, G Camilli, JS Griffiths, JP Richardson, N Kichik, JR Naglik
Immunology 162 (1), 11-16, 2021
622021
NMR analysis of G-protein βγ subunit complexes reveals a dynamic Gα-Gβγ subunit interface and multiple protein recognition modes
AV Smrcka, N Kichik, T Tarragó, M Burroughs, MS Park, NK Itoga, ...
Proceedings of the National Academy of Sciences 107 (2), 639-644, 2010
342010
15N Relaxation NMR Studies of Prolyl Oligopeptidase, an 80 kDa Enzyme, Reveal a Pre‐existing Equilibrium between Different Conformational States
N Kichik, T Tarragó, B Claasen, M Gairí, O Millet, E Giralt
ChemBioChem 12 (18), 2737-2739, 2011
252011
Candidalysins are a new family of cytolytic fungal peptide toxins
JP Richardson, R Brown, N Kichik, S Lee, E Priest, S Mogavero, ...
MBio 13 (1), e03510-21, 2022
242022
Albumin Neutralizes Hydrophobic Toxins and Modulates Candida albicans Pathogenicity
S Austermeier, M Pekmezović, P Porschitz, S Lee, N Kichik, DL Moyes, ...
MBio 12 (3), 10.1128/mbio. 00531-21, 2021
242021
Processing of Candida albicans Ece1p is critical for candidalysin maturation and fungal virulence. mBio 9: e02178-17
JP Richardson, S Mogavero, DL Moyes, M Blagojevic, T Kruger, ...
192018
Simultaneous 19F NMR Screening of Prolyl Oligopeptidase and Dipeptidyl Peptidase IV Inhibitors
N Kichik, T Tarragó, E Giralt
ChemBioChem 11 (8), 1115-1119, 2010
172010
A cost‐effective labeling strategy for the NMR study of large proteins: selective 15N‐labeling of the tryptophan side chains of prolyl oligopeptidase
T Tarragó, B Claasen, N Kichik, RA Rodriguez‐Mias, M Gairí, E Giralt
ChemBioChem 10 (17), 2736-2739, 2009
162009
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis
Y Wu, S Du, LH Bimler, KE Mauk, L Lortal, N Kichik, JS Griffiths, R Osicka, ...
Cell reports 42 (10), 2023
122023
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor. Nat Commun 10: 2297
J Ho, X Yang, SA Nikou, N Kichik, A Donkin, NO Ponde, JP Richardson, ...
112019
NMR analysis of G-protein subunit complexes reveals a dynamic G-G subunit interface and multiple protein recognition modes
AV Smrcka, N Kichik, T Tarragó, M Burroughs, MS Park, NK Itoga, ...
Proceedings of the National Academy of Science 107, 639-644, 2009
32009
In Vitro Biophysical Characterization of Candidalysin: A Fungal Peptide Toxin
S Lee, N Kichik, OW Hepworth, JP Richardson, JR Naglik
Candida Species: Methods and Protocols, 163-176, 2022
22022
NMR analysis of G-protein βγ subunit complexes reveals a dynamic Gα-Gβγ subunit interface and multiple protein recognition modes
AV Smrcka, N Kichik, T TarragÃ, M Burroughs, MS Park, NK Itoga, ...
Proceedings of the National Academy of Sciences of the United States of America, 2010
12010
MECHANISMS FOR INHIBITION OF GBETA/GAMMA SIGNALING BY PROTEINS, PEPTIDES AND SMALL MOLECULES
AV Smrcka, S Malik, P Seneviratne, A Dessal, N Kichik, T Tarrago, E Giralt
JOURNAL OF PHYSIOLOGICAL SCIENCES 59, 56-56, 2009
12009
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