Antibiotics from neglected bacterial sources SJ Pidot, S Coyne, F Kloss, C Hertweck International Journal of Medical Microbiology 304 (1), 14-22, 2014 | 161 | 2014 |
The molecular basis of conjugated polyyne biosynthesis in phytopathogenic bacteria C Ross, K Scherlach, F Kloss, C Hertweck Angewandte Chemie International Edition 53 (30), 7794-7798, 2014 | 91 | 2014 |
Metal‐Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing F Kloss, T Neuwirth, VG Haensch, C Hertweck Angewandte Chemie International Edition 57 (44), 14476-14481, 2018 | 69 | 2018 |
Metal‐Free 1, 5‐Regioselective Azide–Alkyne [3+ 2]‐Cycloaddition F Kloss, U Köhn, BO Jahn, MD Hager, H Görls, US Schubert Chemistry–An Asian Journal 6 (10), 2816-2824, 2011 | 68 | 2011 |
In vivo dearomatization of the potent antituberculosis agent BTZ043 via Meisenheimer complex formation F Kloss, V Krchnak, A Krchnakova, S Schieferdecker, J Dreisbach, ... Angewandte Chemie International Edition 56 (8), 2187-2191, 2017 | 55 | 2017 |
Antiterminator‐Mediated Unveiling of Cryptic Polythioamides in an Anaerobic Bacterium S Behnken, T Lincke, F Kloss, K Ishida, C Hertweck Angewandte Chemie International Edition 51 (10), 2425-2428, 2012 | 55 | 2012 |
Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors AI Chiriac, F Kloss, J Krämer, C Vuong, C Hertweck, HG Sahl Journal of Antimicrobial Chemotherapy 70 (9), 2576-2588, 2015 | 43 | 2015 |
Formation of a Dinuclear Copper(I) Complex from the Clostridium‐Derived Antibiotic Closthioamide F Kloss, S Pidot, H Goerls, T Friedrich, C Hertweck Angewandte Chemie International Edition 52 (41), 10745-10748, 2013 | 41 | 2013 |
Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke L Bitar, T Uphaus, C Thalman, M Muthuraman, L Gyr, H Ji, M Domingues, ... Science translational medicine 14 (641), eabk0135, 2022 | 27 | 2022 |
Highly Efficient Total Synthesis of the Clostridium‐Derived anti‐MRSA Antibiotic Closthioamide F Kloss, T Lincke, C Hertweck European journal of organic chemistry 2011 (8), 1429-1431, 2011 | 27 | 2011 |
Investigation of amino acid containing [FeFe] hydrogenase models concerning pendant base effects UP Apfel, CR Kowol, Y Halpin, F Kloss, J Kübel, H Görls, JG Vos, ... Journal of inorganic biochemistry 103 (9), 1236-1244, 2009 | 25 | 2009 |
AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids H Endle, G Horta, B Stutz, M Muthuraman, I Tegeder, Y Schreiber, ... Nature metabolism 4 (6), 683-692, 2022 | 24 | 2022 |
Mapping of the modular closthioamide architecture reveals crucial motifs of polythioamide antibiotics F Kloss, AI Chiriac, C Hertweck Chemistry–A European Journal 20 (47), 15451-15458, 2014 | 22 | 2014 |
Reconstitution of iterative thioamidation in closthioamide biosynthesis reveals tailoring strategy for nonribosomal peptide backbones KL Dunbar, M Dell, EM Molloy, F Kloss, C Hertweck Angewandte Chemie 131 (37), 13148-13152, 2019 | 20 | 2019 |
Disruption of membrane integrity by the bacterium-derived antifungal jagaricin D Fischer, G Gessner, TP Fill, R Barnett, K Tron, K Dornblut, F Kloss, ... Antimicrobial agents and chemotherapy 63 (9), 10.1128/aac. 00707-19, 2019 | 20 | 2019 |
Metal‐Free Aryl Cross‐Coupling Directed by Traceless Linkers VG Haensch, T Neuwirth, J Steinmetzer, F Kloss, R Beckert, S Gräfe, ... Chemistry–A European Journal 25 (70), 16068-16073, 2019 | 18 | 2019 |
Biosynthetic plasticity enables production of fluorinated aurachins A Sester, K Stüer‐Patowsky, W Hiller, F Kloss, S Lütz, M Nett ChemBioChem 21 (16), 2268-2273, 2020 | 16 | 2020 |
Hydroxy and ether functionalized dithiolanes: Models for the active site of the [FeFe] hydrogenase UP Apfel, CR Kowol, F Kloss, H Görls, BK Keppler, W Weigand Journal of Organometallic Chemistry 696 (5), 1084-1088, 2011 | 16 | 2011 |
Synthesis and characterization of chiral 1, 2-diamines from 5-oxo-pyrrolidine-(S)-2-carboxylic acid U Koehn, A Schramm, F Kloss, H Goerls, E Arnold, E Anders Tetrahedron: Asymmetry 18 (14), 1735-1741, 2007 | 13 | 2007 |
Natural products in antibiotic development: is the success story over? FA Bernal, P Hammann, F Kloss Current Opinion in Biotechnology 78, 102783, 2022 | 10 | 2022 |