A one-hit model of cell death in inherited neuronal degenerations G Clarke, RA Collins, BR Leavitt, DF Andrews, MR Hayden, CJ Lumsden, ... Nature 406 (6792), 195-199, 2000 | 357 | 2000 |
Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis G Clarke, AFX Goldberg, D Vidgen, L Collins, L Ploder, L Schwarz, ... Nature genetics 25 (1), 67-73, 2000 | 194 | 2000 |
Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosa W Kedzierski, S Nusinowitz, D Birch, G Clarke, RR McInnes, D Bok, ... Proceedings of the National Academy of Sciences 98 (14), 7718-7723, 2001 | 88 | 2001 |
Inherited neurodegenerative diseases: the one-hit model of neurodegeneration G Clarke, CJ Lumsden, RR McInnes Human molecular genetics 10 (20), 2269-2275, 2001 | 83 | 2001 |
Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells F Moledina, G Clarke, A Oskooei, K Onishi, A Günther, PW Zandstra Proceedings of the National Academy of Sciences 109 (9), 3264-3269, 2012 | 77 | 2012 |
Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics MD Ungrin, G Clarke, T Yin, S Niebrugge, MC Nostro, F Sarangi, G Wood, ... Biotechnology and bioengineering 109 (4), 853-866, 2012 | 61 | 2012 |
Recent advances in the molecular basis of inherited photoreceptor degeneration G Clarke, E Héon, RR McInnes Clinical genetics 57 (5), 313-329, 2000 | 50 | 2000 |
Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks SA Yuzwa, G Yang, MJ Borrett, G Clarke, GI Cancino, SK Zahr, ... Neuron 91 (5), 988-1004, 2016 | 49 | 2016 |
Scale-free neurodegeneration: cellular heterogeneity and the stretched exponential kinetics of cell death G Clarke, CJ Lumsden Journal of theoretical biology 233 (4), 515-525, 2005 | 31 | 2005 |
Photoreceptor death: spatiotemporal patterns arising from one-hit death kinetics and a diffusible cell death factor J Burns, G Clarke, CJ Lumsden Bulletin of mathematical biology 64 (6), 1117-1145, 2002 | 30 | 2002 |
Heterogeneous cellular environments modulate one-hit neuronal death kinetics G Clarke, CJ Lumsden Brain research bulletin 65 (1), 59-67, 2005 | 27 | 2005 |
One-hit stochastic decline in a mechanochemical model of cytoskeleton-induced neuron death II: Transition state metastability T Lomasko, G Clarke, CJ Lumsden Journal of theoretical biology 249 (1), 18-28, 2007 | 8 | 2007 |
One-hit stochastic decline in a mechanochemical model of cytoskeleton-induced neuron death I: Cell-fate arrival times T Lomasko, G Clarke, CJ Lumsden Journal of theoretical biology 249 (1), 1-17, 2007 | 7 | 2007 |
Addendum: a one-hit model of cell death in inherited neuronal degenerations G Clarke, RA Collins, BR Leavitt, DF Andrews, MR Hayden, CJ Lumsden, ... Nature 409 (6819), 542-542, 2001 | 4 | 2001 |
Computational Modeling and Stem Cell Engineering PW Zandstra, G Clarke Stem Cell Engineering, 65-97, 2014 | 2 | 2014 |
A one-hit model of cell death in inherited neuronal degeneration G CLARKE Nature 406, 1995-1999, 2000 | 2 | 2000 |
A Stochastic model of the mutant steady state (MSS): Bistability and the commitment to apoptotic cell death G Clarke, CJ Lumsden MOLECULAR BIOLOGY OF THE CELL 13, 276A-276A, 2002 | | 2002 |
ERG's in mice with RDS/peripherin and ROM1 mutations DG Birch, K Locke, G Clarke, R McInnes, GH Travis INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38 (4), 1480-1480, 1997 | | 1997 |
Digenic inheritance of photoreceptor degeneration in mice with mutations in the genes for both rds and rom1 GH Travis, W Kedzierski, G Clarke, D Birch, RR McInnes, D Bok INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38 (4), 3252-3252, 1997 | | 1997 |