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Geoff Clarke
Geoff Clarke
在 utoronto.ca 的电子邮件经过验证
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A one-hit model of cell death in inherited neuronal degenerations
G Clarke, RA Collins, BR Leavitt, DF Andrews, MR Hayden, CJ Lumsden, ...
Nature 406 (6792), 195-199, 2000
3572000
Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis
G Clarke, AFX Goldberg, D Vidgen, L Collins, L Ploder, L Schwarz, ...
Nature genetics 25 (1), 67-73, 2000
1942000
Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosa
W Kedzierski, S Nusinowitz, D Birch, G Clarke, RR McInnes, D Bok, ...
Proceedings of the National Academy of Sciences 98 (14), 7718-7723, 2001
882001
Inherited neurodegenerative diseases: the one-hit model of neurodegeneration
G Clarke, CJ Lumsden, RR McInnes
Human molecular genetics 10 (20), 2269-2275, 2001
832001
Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells
F Moledina, G Clarke, A Oskooei, K Onishi, A Günther, PW Zandstra
Proceedings of the National Academy of Sciences 109 (9), 3264-3269, 2012
772012
Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics
MD Ungrin, G Clarke, T Yin, S Niebrugge, MC Nostro, F Sarangi, G Wood, ...
Biotechnology and bioengineering 109 (4), 853-866, 2012
612012
Recent advances in the molecular basis of inherited photoreceptor degeneration
G Clarke, E Héon, RR McInnes
Clinical genetics 57 (5), 313-329, 2000
502000
Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks
SA Yuzwa, G Yang, MJ Borrett, G Clarke, GI Cancino, SK Zahr, ...
Neuron 91 (5), 988-1004, 2016
492016
Scale-free neurodegeneration: cellular heterogeneity and the stretched exponential kinetics of cell death
G Clarke, CJ Lumsden
Journal of theoretical biology 233 (4), 515-525, 2005
312005
Photoreceptor death: spatiotemporal patterns arising from one-hit death kinetics and a diffusible cell death factor
J Burns, G Clarke, CJ Lumsden
Bulletin of mathematical biology 64 (6), 1117-1145, 2002
302002
Heterogeneous cellular environments modulate one-hit neuronal death kinetics
G Clarke, CJ Lumsden
Brain research bulletin 65 (1), 59-67, 2005
272005
One-hit stochastic decline in a mechanochemical model of cytoskeleton-induced neuron death II: Transition state metastability
T Lomasko, G Clarke, CJ Lumsden
Journal of theoretical biology 249 (1), 18-28, 2007
82007
One-hit stochastic decline in a mechanochemical model of cytoskeleton-induced neuron death I: Cell-fate arrival times
T Lomasko, G Clarke, CJ Lumsden
Journal of theoretical biology 249 (1), 1-17, 2007
72007
Addendum: a one-hit model of cell death in inherited neuronal degenerations
G Clarke, RA Collins, BR Leavitt, DF Andrews, MR Hayden, CJ Lumsden, ...
Nature 409 (6819), 542-542, 2001
42001
Computational Modeling and Stem Cell Engineering
PW Zandstra, G Clarke
Stem Cell Engineering, 65-97, 2014
22014
A one-hit model of cell death in inherited neuronal degeneration
G CLARKE
Nature 406, 1995-1999, 2000
22000
A Stochastic model of the mutant steady state (MSS): Bistability and the commitment to apoptotic cell death
G Clarke, CJ Lumsden
MOLECULAR BIOLOGY OF THE CELL 13, 276A-276A, 2002
2002
ERG's in mice with RDS/peripherin and ROM1 mutations
DG Birch, K Locke, G Clarke, R McInnes, GH Travis
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38 (4), 1480-1480, 1997
1997
Digenic inheritance of photoreceptor degeneration in mice with mutations in the genes for both rds and rom1
GH Travis, W Kedzierski, G Clarke, D Birch, RR McInnes, D Bok
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38 (4), 3252-3252, 1997
1997
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