Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors DA Wainwright, AL Chang, M Dey, IV Balyasnikova, CK Kim, A Tobias, ... Clinical cancer research 20 (20), 5290-5301, 2014 | 613 | 2014 |
CCL2 produced by the glioma microenvironment is essential for the recruitment of regulatory T cells and myeloid-derived suppressor cells AL Chang, J Miska, DA Wainwright, M Dey, CV Rivetta, D Yu, D Kanojia, ... Cancer research 76 (19), 5671-5682, 2016 | 555 | 2016 |
IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival DA Wainwright, IV Balyasnikova, AL Chang, AU Ahmed, KS Moon, ... Clinical cancer research 18 (22), 6110-6121, 2012 | 460 | 2012 |
NK cell-based cancer immunotherapy: from basic biology to clinical development S Liu, V Galat, Y Galat4, YKA Lee, D Wainwright, J Wu Journal of hematology & oncology 14, 1-17, 2021 | 445 | 2021 |
IDO1 in cancer: a Gemini of immune checkpoints L Zhai, E Ladomersky, A Lenzen, B Nguyen, R Patel, KL Lauing, M Wu, ... Cellular & molecular immunology 15 (5), 447-457, 2018 | 324 | 2018 |
Molecular pathways: targeting IDO1 and other tryptophan dioxygenases for cancer immunotherapy L Zhai, S Spranger, DC Binder, G Gritsina, KL Lauing, FJ Giles, ... Clinical cancer research 21 (24), 5427-5433, 2015 | 292 | 2015 |
Blood‐brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging Y Cheng, Q Dai, RA Morshed, X Fan, ML Wegscheid, DA Wainwright, ... Small 10 (24), 5137-5150, 2014 | 272 | 2014 |
Reduced skin homing by functional Treg in vitiligo J Klarquist, CJ Denman, C Hernandez, DJ Wainwright, FM Strickland, ... Pigment cell & melanoma research 23 (2), 276-286, 2010 | 202 | 2010 |
IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma E Ladomersky, L Zhai, A Lenzen, KL Lauing, J Qian, DM Scholtens, ... Clinical cancer research 24 (11), 2559-2573, 2018 | 170 | 2018 |
Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma EJ Chung, Y Cheng, R Morshed, K Nord, Y Han, ML Wegscheid, ... Biomaterials 35 (4), 1249-1256, 2014 | 163 | 2014 |
Immunosuppressive IDO in cancer: mechanisms of action, animal models, and targeting strategies L Zhai, A Bell, E Ladomersky, KL Lauing, L Bollu, JA Sosman, B Zhang, ... Frontiers in immunology 11, 1185, 2020 | 158 | 2020 |
Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival L Zhai, E Ladomersky, KL Lauing, M Wu, M Genet, G Gritsina, B Győrffy, ... Clinical Cancer Research 23 (21), 6650-6660, 2017 | 153 | 2017 |
Newly diagnosed glioblastoma: a review on clinical management RV Lukas, DA Wainwright, E Ladomersky, S Sachdev, AM Sonabend, ... Oncology (Williston Park, NY) 33 (3), 91, 2019 | 142 | 2019 |
Targeting Tregs in malignant brain cancer: overcoming IDO DA Wainwright, M Dey, A Chang, MS Lesniak Frontiers in immunology 4, 116, 2013 | 136 | 2013 |
Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors DA Wainwright, S Sengupta, Y Han, MS Lesniak Neuro-oncology 13 (12), 1308-1323, 2011 | 131 | 2011 |
The challenge for gene therapy: innate immune response to adenoviruses B Thaci, IV Ulasov, DA Wainwright, MS Lesniak Oncotarget 2 (3), 113, 2011 | 128 | 2011 |
The coincidence between increasing age, immunosuppression, and the incidence of patients with glioblastoma E Ladomersky, DM Scholtens, M Kocherginsky, EA Hibler, ET Bartom, ... Frontiers in pharmacology 10, 200, 2019 | 119 | 2019 |
Targeting CD73 to augment cancer immunotherapy M Roh, DA Wainwright, JD Wu, Y Wan, B Zhang Current opinion in pharmacology 53, 66-76, 2020 | 110 | 2020 |
IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection J Xin, DA Wainwright, NA Mesnard, CJ Serpe, VM Sanders, KJ Jones Brain, behavior, and immunity 25 (5), 820-829, 2011 | 103 | 2011 |
The role of IDO in brain tumor immunotherapy L Zhai, KL Lauing, AL Chang, M Dey, J Qian, Y Cheng, MS Lesniak, ... Journal of neuro-oncology 123, 395-403, 2015 | 102 | 2015 |