Fluorescent fusion protein knockout mediated by anti-GFP nanobody E Caussinus, O Kanca, M Affolter Nature structural & molecular biology 19 (1), 117-121, 2012 | 535 | 2012 |
A gene-specific T2A-GAL4 library for Drosophila PT Lee, J Zirin, O Kanca, WW Lin, KL Schulze, D Li-Kroeger, R Tao, ... elife 7, e35574, 2018 | 224 | 2018 |
An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms O Kanca, J Zirin, J Garcia-Marques, SM Knight, D Yang-Zhou, G Amador, ... Elife 8, e51539, 2019 | 117 | 2019 |
IRF2BPL is associated with neurological phenotypes PC Marcogliese, V Shashi, RC Spillmann, N Stong, JA Rosenfeld, ... The American Journal of Human Genetics 103 (2), 245-260, 2018 | 94 | 2018 |
Lipid microdomain clustering induces a redistribution of antigen recognition and adhesion molecules on human T lymphocytes JS Mitchell, O Kanca, BW McIntyre The Journal of Immunology 168 (6), 2737-2744, 2002 | 68 | 2002 |
An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila D Li-Kroeger, O Kanca, PT Lee, S Cowan, MT Lee, M Jaiswal, JL Salazar, ... Elife 7, e38709, 2018 | 64 | 2018 |
Raeppli: a whole-tissue labeling tool for live imaging of Drosophila development O Kanca, E Caussinus, AS Denes, A Percival-Smith, M Affolter Development 141 (2), 472-480, 2014 | 64 | 2014 |
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila O Kanca, HJ Bellen, F Schnorrer Genetics 207 (2), 389-412, 2017 | 63 | 2017 |
De novo variants in WDR37 are associated with epilepsy, colobomas, dysmorphism, developmental delay, intellectual disability, and cerebellar hypoplasia O Kanca, JC Andrews, PT Lee, C Patel, SR Braddock, AM Slavotinek, ... The American Journal of Human Genetics 105 (2), 413-424, 2019 | 50 | 2019 |
An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination O Kanca, J Zirin, Y Hu, B Tepe, D Dutta, WW Lin, L Ma, M Ge, Z Zuo, ... Elife 11, e76077, 2022 | 36 | 2022 |
De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment D Dutta, LC Briere, O Kanca, PC Marcogliese, MA Walker, FA High, ... Human Molecular Genetics 29 (9), 1568-1579, 2020 | 32 | 2020 |
Establishment of a Developmental Compartment Requires Interactions between Three Synergistic Cis-regulatory Modules D Bieli, O Kanca, D Requena, F Hamaratoglu, D Gohl, P Schedl, ... PLoS genetics 11 (10), e1005376, 2015 | 30 | 2015 |
Protein knockouts in living eukaryotes using deGradFP and green fluorescent protein fusion targets E Caussinus, O Kanca, M Affolter Current protocols in protein science 73 (1), 30.2. 1-30.2. 13, 2013 | 27 | 2013 |
Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases PC Marcogliese, SL Deal, J Andrews, JM Harnish, VH Bhavana, ... Cell reports 38 (11), 2022 | 25 | 2022 |
TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila LD Goodman, H Cope, Z Nil, TA Ravenscroft, WL Charng, S Lu, AC Tien, ... The American Journal of Human Genetics 108 (9), 1669-1691, 2021 | 23 | 2021 |
Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation H Chung, Q Ye, YJ Park, Z Zuo, JW Mok, O Kanca, SG Tattikota, S Lu, ... Cell Metabolism 35 (5), 855-874. e5, 2023 | 18 | 2023 |
Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling PC Marcogliese, D Dutta, SS Ray, NDP Dang, Z Zuo, Y Wang, D Lu, ... Science advances 8 (3), eabl5613, 2022 | 17 | 2022 |
Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans S Yamamoto, O Kanca, MF Wangler, HJ Bellen Nature Reviews Genetics 25 (1), 46-60, 2024 | 15 | 2024 |
Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11 TA Ravenscroft, JB Phillips, E Fieg, SS Bajikar, J Peirce, J Wegner, ... Genetics in medicine 23 (10), 1889-1900, 2021 | 14 | 2021 |
The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer D Bieli, O Kanca, D Gohl, A Denes, P Schedl, M Affolter, M Müller G3: Genes, Genomes, Genetics 5 (6), 1129-1143, 2015 | 14 | 2015 |