Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to … KM Frey, J Liu, MN Lombardo, DB Bolstad, DL Wright, AC Anderson Journal of molecular biology 387 (5), 1298-1308, 2009 | 60 | 2009 |
Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting Bacillus anthracis Dihydrofolate Reductase JM Beierlein, KM Frey, DB Bolstad, PM Pelphrey, TM Joska, AE Smith, ... Journal of medicinal chemistry 51 (23), 7532-7540, 2008 | 48 | 2008 |
Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase J Liu, DB Bolstad, AE Smith, ND Priestley, DL Wright, AC Anderson Chemistry & biology 15 (9), 990-996, 2008 | 48 | 2008 |
Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from Cryptosporidium DB Bolstad, ESD Bolstad, KM Frey, DL Wright, AC Anderson Journal of medicinal chemistry 51 (21), 6839-6852, 2008 | 46 | 2008 |
Probing the Active Site of Candida glabrata Dihydrofolate Reductase with High Resolution Crystal Structures and the Synthesis of New Inhibitors J Liu, DB Bolstad, AE Smith, ND Priestley, DL Wright, AC Anderson Chemical biology & drug design 73 (1), 62-74, 2009 | 30 | 2009 |
Towards new antifolates targeting eukaryotic opportunistic infections J Liu, DB Bolstad, ESD Bolstad, DL Wright, AC Anderson Eukaryotic cell 8 (4), 483-486, 2009 | 28 | 2009 |
Synthesis and Characterization of Nanocrystalline Y2O3: Eu 3+ Phosphor. An Upper-Division Inorganic Chemistry Laboratory DB Bolstad, AL Diaz Journal of chemical education 79 (9), 1101, 2002 | 25 | 2002 |
In vitro biological activity and structural analysis of 2, 4-diamino-5-(2′-arylpropargyl) pyrimidine inhibitors of Candida albicans JL Paulsen, J Liu, DB Bolstad, AE Smith, ND Priestley, DL Wright, ... Bioorganic & medicinal chemistry 17 (14), 4866-4872, 2009 | 19 | 2009 |
Versatile oxabicyclic synthons: Studies on C8-oxygenated eunicellin Diterpenes PM Pelphrey, DB Bolstad, DL Wright Synlett 2007 (17), 2647-2650, 2007 | 9 | 2007 |
Dihydrofolate reductase inhibitors: developments in antiparasitic chemotherapy DB Bolstad, ESD Bolstad, DL Wright, AC Anderson Expert Opinion on Therapeutic Patents 18 (2), 143-157, 2008 | 6 | 2008 |
Inhibitors of dihydrofolate reductase with antibacterial antiprotozoal, antifungal and anticancer properties AC Anderson, DL Wright, PM Pelphrey, TM Joska, ESD Bolstad, ... US Patent 8,426,432, 2013 | 4 | 2013 |
New serotonin transporter radioligands:(±)-[18F] 2-methoxyfluoropropyl-6-nitroquizapine JM Gerdes, JP ONeil, DB Bolstadt Neuroimage 22, 2004 | 4 | 2004 |
The crystal structure of Candida glabrata dihydrofolate reductase drives new inhibitor design toward efficacious antifungal agents J Liu, DB Bolstad, AE Smith, ND Priestley, DL Wright, AC Anderson Chemistry & biology 15 (9), 990, 2008 | 3 | 2008 |
1-[(2'-substituted)-piperazin-1'-yl]-isoquinolines as norepinephrine transporter inhibitor therapeutics and positron emission tomography imaging agents JM Gerdes, DB Bolstad, MR Braden, AW Barany | 2 | 2008 |
Sertonin transporter inhibitor ligands: Synthesis and biochemical studies of 2'-methoxymethyl-6-nitroquipazine. DB Bolstad, D Chandler-Ferguson, SC DeFina, JM Gerdes, MA Walker, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 222, U648-U648, 2001 | 2 | 2001 |
Therapeutic compounds for protozoal and microbial infections and cancer JH Hoody, DB Bolstad US Patent App. 13/803,648, 2013 | 1 | 2013 |
Enantiomers of 2'-Fluoralky1-6-nitroquipazine as serotonin transporter positron emission tomography imaging agents and antidepressant therapeutics JM Gerdes, DB Bolstad, BR Kusche US Patent 7,998,962, 2011 | 1 | 2011 |
1-[(2′-substituted)-piperazin-1′-yl]-isoquinolines as norepinephrine transporter inhibitor therapeutics and positron emission tomography imaging agents JM Gerdes, DB Bolstad, MR Braden, AW Barany US Patent 7,887,784, 2011 | 1 | 2011 |
Enantiomers of 2′-fluoralkyl-6-nitroquipazine as serotonin transporter positron emission tomography imaging agents and antidepressant therapeutics JM Gerdes, DB Bolstad, BR Kusche US Patent 7,812,162, 2010 | 1 | 2010 |
Serotonin Transporter Ligands: Synthesis of (+/-)-[^ 1^ 1C] 2'-Methoxymethyl-6-Nitroquipazine JP O Neil, HF VanBrocklin, JM Gerdes, DB Bolstad, BR Kusche JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 46, S171-S171, 2003 | 1 | 2003 |