Structural insight into the inhibition of tubulin by vinca domain peptide ligands A Cormier, M Marchand, RBG Ravelli, M Knossow, B Gigant EMBO reports 9 (11), 1101-1106, 2008 | 184 | 2008 |
Cryo-EM reveals integrin-mediated TGF-β activation without release from latent TGF-β MG Campbell, A Cormier, S Ito, RI Seed, AJ Bondesson, J Lou, JD Marks, ... Cell 180 (3), 490-501. e16, 2020 | 142 | 2020 |
Integrin αvβ8–expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells N Takasaka, RI Seed, A Cormier, AJ Bondesson, J Lou, A Elattma, S Ito, ... JCI Insight 3 (20), 2018 | 103 | 2018 |
Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease S Minagawa, J Lou, RI Seed, A Cormier, S Wu, Y Cheng, L Murray, P Tsui, ... Science translational medicine 6 (241), 241ra79-241ra79, 2014 | 96 | 2014 |
Microtubule-destabilizing agents: structural and mechanistic insights from the interaction of colchicine and vinblastine with tubulin B Gigant, A Cormier, A Dorléans, RBG Ravelli, M Knossow Tubulin-Binding Agents, 259-278, 2009 | 76 | 2009 |
The PN2-3 domain of centrosomal P4. 1-associated protein implements a novel mechanism for tubulin sequestration A Cormier, MJ Clément, M Knossow, S Lachkar, P Savarin, F Toma, ... Journal of Biological Chemistry 284 (11), 6909-6917, 2009 | 58 | 2009 |
Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics Y Nakajima, A Cormier, RG Tyers, A Pigula, Y Peng, DG Drubin, G Barnes Journal of Cell Biology 194 (1), 137-153, 2011 | 56 | 2011 |
Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension. A Cormier, MG Campbell, S Ito, S Wu, J Lou, J Marks, JL Baron, ... Nature Structural and Molecular Biology, 2018 | 55 | 2018 |
Synthesis and biological evaluation of vinca alkaloids and phomopsin hybrids QA Ngo, F Roussi, A Cormier, S Thoret, M Knossow, D Guénard, ... Journal of medicinal chemistry 52 (1), 134-142, 2009 | 50 | 2009 |
The binding of vinca domain agents to tubulin: structural and biochemical studies A Cormier, M Knossow, C Wang, B Gigant Methods in cell biology 95, 373-390, 2010 | 38 | 2010 |
Insight into the GTPase activity of tubulin from complexes with stathmin-like domains C Wang, A Cormier, B Gigant, M Knossow Biochemistry 46 (37), 10595-10602, 2007 | 34 | 2007 |
A tumor-specific mechanism of Treg enrichment mediated by the integrin αvβ8 RI Seed, K Kobayashi, S Ito, N Takasaka, A Cormier, JM Jespersen, ... Science immunology 6 (57), eabf0558, 2021 | 21 | 2021 |
Phosphorylation regulates kinase and microtubule binding activities of the budding yeast Chromosomal Passenger Complex in vitro A Cormier, DG Drubin, G Barnes Journal of Biological Chemistry 288 (32), 23203-23211, 2013 | 18 | 2013 |
A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A J Lou, W Wen, F Conrad, Q Meng, J Dong, Z Sun, C Garcia-Rodriguez, ... Toxins 10 (2), 84, 2018 | 12 | 2018 |
Integrin αvβ8-expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells. JCI insight. 2018 N Takasaka, RI Seed, A Cormier, AJ Bondesson, J Lou, A Elattma, S Ito, ... DOI: https://doi. org/10.1172/jci. insight 122591, 2018 | 8 | 2018 |
Neutralizing antibodies to the αvβ8 integrin complex for immunotherapy SL Nishimura, J Lou, JD Marks, JL Baron, Y Cheng, WU Shenping, ... US Patent 10,954,304, 2021 | 2 | 2021 |
Antibodies that bind integrin AVB8 and uses thereof SL Nishimura, A Cormier, S Ito, J Lou, JD Marks, Y Cheng, MG Campbell, ... US Patent 11,608,378, 2023 | 1 | 2023 |
Dynamic allostery drives autocrine and paracrine TGF-β signaling M Jin, RI Seed, G Cai, T Shing, L Wang, S Ito, A Cormier, SA Wankowicz, ... Cell, 2024 | | 2024 |
Neutralizing antibodies to the alpha v beta 8 integrin complex for immunotherapy SL Nishimura, J Lou, JD Marks, JL Baron, Y Cheng, WU Shenping, ... US Patent App. 18/153,277, 2023 | | 2023 |
Antibodies that bind integrin avb8 and uses thereof SL NISHIMURA, A Cormier, S Ito, J Lou, JD Marks, Y CHENG, ... US Patent App. 18/153,103, 2023 | | 2023 |