Activated Wnt/ß-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model AJ Chien, EC Moore, AS Lonsdorf, RM Kulikauskas, BG Rothberg, ... Proceedings of the National Academy of Sciences 106 (4), 1193-1198, 2009 | 445 | 2009 |
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity O Speck, SC Hughes, NK Noren, RM Kulikauskas, RG Fehon Nature 421 (6918), 83-87, 2003 | 317 | 2003 |
Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA KG Paulson, V Voillet, MS McAfee, DS Hunter, FD Wagener, M Perdicchio, ... Nature communications 9 (1), 3868, 2018 | 256 | 2018 |
The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling S Maitra, RM Kulikauskas, H Gavilan, RG Fehon Current Biology 16 (7), 702-709, 2006 | 237 | 2006 |
WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors JN Anastas, RM Kulikauskas, T Tamir, H Rizos, GV Long, EM Von Euw, ... The Journal of clinical investigation 124 (7), 2877-2890, 2014 | 223 | 2014 |
Neoadjuvant nivolumab for patients with resectable Merkel cell carcinoma in the CheckMate 358 trial SL Topalian, S Bhatia, A Amin, RR Kudchadkar, WH Sharfman, C Lebbé, ... Journal of Clinical Oncology 38 (22), 2476-2487, 2020 | 208 | 2020 |
Wnt/β-Catenin Signaling and AXIN1 Regulate Apoptosis Triggered by Inhibition of the Mutant Kinase BRAFV600E in Human Melanoma TL Biechele, RM Kulikauskas, RA Toroni, OM Lucero, RD Swift, ... Science signaling 5 (206), ra3-ra3, 2012 | 197 | 2012 |
The Neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation BM McCartney, RM Kulikauskas, DR LaJeunesse, RG Fehon Development 127 (6), 1315-1324, 2000 | 185 | 2000 |
Self-masking in an intact ERM-merlin protein: an active role for the central α-helical domain Q Li, MR Nance, R Kulikauskas, K Nyberg, R Fehon, PA Karplus, ... Journal of molecular biology 365 (5), 1446-1459, 2007 | 160 | 2007 |
WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma MD Arensman, AN Kovochich, RM Kulikauskas, AR Lay, PT Yang, X Li, ... Oncogene 33 (7), 899-908, 2014 | 136 | 2014 |
Intratumoral G100, a TLR4 agonist, induces antitumor immune responses and tumor regression in patients with Merkel cell carcinoma S Bhatia, NJ Miller, H Lu, NV Longino, D Ibrani, MM Shinohara, DR Byrd, ... Clinical Cancer Research 25 (4), 1185-1195, 2019 | 119 | 2019 |
Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail ZF Zimmerman, RM Kulikauskas, K Bomsztyk, RT Moon, AJ Chien PloS one 8 (7), e69593, 2013 | 97 | 2013 |
Intratumoral delivery of plasmid IL12 via electroporation leads to regression of injected and noninjected tumors in Merkel cell carcinoma S Bhatia, NV Longino, NJ Miller, R Kulikauskas, JG Iyer, D Ibrani, A Blom, ... Clinical Cancer Research 26 (3), 598-607, 2020 | 78 | 2020 |
New pollen-specific receptor kinases identified in tomato, maize and Arabidopsis: the tomato kinases show overlapping but distinct localization patterns on pollen … HU Kim, R Cotter, S Johnson, M Senda, P Dodds, R Kulikauskas, W Tang, ... Plant Molecular Biology 50, 1-16, 2002 | 76 | 2002 |
Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma TL Biechele, ND Camp, DM Fass, RM Kulikauskas, NC Robin, BD White, ... Chemistry & biology 17 (11), 1177-1182, 2010 | 75 | 2010 |
WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner K Brown, P Yang, D Salvador, R Kulikauskas, H Ruohola-Baker, ... Oncogene 36 (22), 3119-3136, 2017 | 69 | 2017 |
Identification of the tobacco and Arabidopsis homologues of the pollen-expressed LAT59 gene of tomato R Kulikauskas, S McCormick Plant Molecular Biology 34, 809-814, 1997 | 63 | 1997 |
Regulating the response to targeted MEK inhibition in melanoma: Enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation WH Conrad, RD Swift, TL Biechele, RM Kulikauskas, RT Moon, AJ Chien Cell cycle 11 (20), 3724-3730, 2012 | 45 | 2012 |
Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy NJ Miller, CD Church, SP Fling, R Kulikauskas, N Ramchurren, ... Journal for immunotherapy of cancer 6, 1-9, 2018 | 40 | 2018 |
Targeted BRAF inhibition impacts survival in melanoma patients with high levels of Wnt/β-catenin signaling AJ Chien, LE Haydu, TL Biechele, RM Kulikauskas, H Rizos, RF Kefford, ... PloS one 9 (4), e94748, 2014 | 40 | 2014 |