Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ... Cell reports 23 (1), 239-254. e6, 2018 | 924 | 2018 |
Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair E Berkovich, RJ Monnat Jr, MB Kastan Nature cell biology 9 (6), 683-690, 2007 | 551 | 2007 |
Mutator phenotype of Werner syndrome is characterized by extensive deletions. K Fukuchi, GM Martin, RJ Monnat Jr Proceedings of the National Academy of Sciences 86 (15), 5893-5897, 1989 | 538 | 1989 |
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition M Berti, A Ray Chaudhuri, S Thangavel, S Gomathinayagam, S Kenig, ... Nature structural & molecular biology 20 (3), 347-354, 2013 | 462 | 2013 |
Computational redesign of endonuclease DNA binding and cleavage specificity J Ashworth, JJ Havranek, CM Duarte, D Sussman, RJ Monnat Jr, ... Nature 441 (7093), 656-659, 2006 | 434 | 2006 |
DNA polymerases and human disease LA Loeb, RJ Monnat Jr Nature Reviews Genetics 9 (8), 594-604, 2008 | 394 | 2008 |
Design, activity, and structure of a highly specific artificial endonuclease BS Chevalier, T Kortemme, MS Chadsey, D Baker, RJ Monnat, ... Molecular cell 10 (4), 895-905, 2002 | 356 | 2002 |
Werner and Hutchinson–Gilford progeria syndromes: mechanistic basis of human progeroid diseases BA Kudlow, BK Kennedy, RJ Monnat Jr Nature reviews Molecular cell biology 8 (5), 394-404, 2007 | 345 | 2007 |
Homologous recombination resolution defect in Werner syndrome Y Saintigny, K Makienko, C Swanson, MJ Emond, RJ Monnat Jr Molecular and cellular biology 22 (20), 6971-6978, 2002 | 306 | 2002 |
Werner syndrome: clinical features, pathogenesis and potential therapeutic interventions J Oshima, JM Sidorova, RJ Monnat Jr Ageing research reviews 33, 105-114, 2017 | 285 | 2017 |
DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI KE Flick, MS Jurica, RJ Monnat Jr, BL Stoddard Nature 394 (6688), 96-101, 1998 | 281 | 1998 |
Spectrum and risk of neoplasia in Werner syndrome: a systematic review JM Lauper, A Krause, TL Vaughan, RJ Monnat Jr PloS one 8 (4), e59709, 2013 | 216 | 2013 |
DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-Cre I MS Jurica, RJ Monnat, BL Stoddard Molecular cell 2 (4), 469-476, 1998 | 209 | 1998 |
The structure of I-Crel, a Group I intron-encoded homing endonuclease PJ Heath, KM Stephens, RJ Monnat Jr, BL Stoddard Nature structural biology 4 (6), 468-476, 1997 | 196 | 1997 |
Somatic mutations are frequent and increase with age in human kidney epithelial cells GM Martin, CE Ogburn, LM Colgin, AM Gown, SD Edland, RJ Monnat Jr Human Molecular Genetics 5 (2), 215-221, 1996 | 173 | 1996 |
I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment GM Argast, KM Stephens, MJ Emond, RJ Monnat Jr Journal of molecular biology 280 (3), 345-353, 1998 | 169 | 1998 |
The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest JM Sidorova, N Li, A Folch, RJ Monnat, Jr Cell cycle 7 (6), 796-807, 2008 | 160 | 2008 |
Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation S Thangavel, R Mendoza-Maldonado, E Tissino, JM Sidorova, J Yin, ... Molecular and cellular biology 30 (6), 1382-1396, 2010 | 157 | 2010 |
Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease A McConnell Smith, R Takeuchi, S Pellenz, L Davis, N Maizels, ... Proceedings of the National Academy of Sciences 106 (13), 5099-5104, 2009 | 157 | 2009 |
Nucleotide sequence preservation of human mitochondrial DNA. RJ Monnat Jr, LA Loeb Proceedings of the National Academy of Sciences 82 (9), 2895-2899, 1985 | 157 | 1985 |