| Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation R Rong, LY Jiang, MS Sheikh, Y Huang Oncogene 26 (55), 7700-7708, 2007 | 112 | 2007 |
| Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy M Holderfield, BJ Lee, J Jiang, A Tomlinson, KJ Seamon, A Mira, ... Nature, 1-8, 2024 | 75 | 2024 |
| Decision making by p53: life versus death L Jiang, MS Sheikh, Y Huang Molecular and cellular pharmacology 2 (2), 69, 2010 | 74 | 2010 |
| Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer H Sun, L Jiang, X Luo, W Jin, Q He, J An, K Lui, J Shi, R Rong, W Su, ... Oncogene 32 (2), 234-241, 2013 | 56 | 2013 |
| PDRG1, a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress L Jiang, X Luo, J Shi, H Sun, Q Sun, MS Sheikh, Y Huang Cancer biology & therapy 11 (6), 567-573, 2011 | 53 | 2011 |
| Translational and therapeutic evaluation of RAS-GTP inhibition by RMC-6236 in RAS-driven cancers J Jiang, L Jiang, BJ Maldonato, Y Wang, M Holderfield, I Aronchik, ... Cancer Discovery 14 (6), 994-1017, 2024 | 51 | 2024 |
| A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation C Yanchus, KL Drucker, TM Kollmeyer, R Tsai, W Winick-Ng, M Liang, ... Science 378 (6615), 68-78, 2022 | 47 | 2022 |
| Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Nature, 1-3, 2024 | 46 | 2024 |
| Lappaol F, a Novel Anticancer Agent Isolated from Plant Arctium Lappa L. Q Sun, K Liu, X Shen, W Jin, L Jiang, M Saeed Sheikh, Y Hu, Y Huang Molecular cancer therapeutics 13 (1), 49-59, 2014 | 46 | 2014 |
| Cullin-4A· DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis L Jiang, R Rong, MS Sheikh, Y Huang Journal of Biological Chemistry 286 (9), 6971-6978, 2011 | 43 | 2011 |
| Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas K Isaev, L Jiang, S Wu, CA Lee, V Watters, V Fort, R Tsai, FJ Coutinho, ... Cell Reports 37 (3), 2021 | 25 | 2021 |
| RMC-9805, a first-in-class, mutant-selective, covalent and oral KRASG12D (ON) inhibitor that induces apoptosis and drives tumor regression in preclinical models of KRASG12D cancers L Jiang, M Menard, C Weller, Z Wang, L Burnett, I Aronchik, S Steele, ... Cancer Research 83 (7_Supplement), 526-526, 2023 | 23 | 2023 |
| Mitotic arrest by tumor suppressor RASSF1A is regulated via CHK1 phosphorylation L Jiang, R Rong, MS Sheikh, Y Huang Molecular Cancer Research 12 (1), 119-129, 2014 | 10 | 2014 |
| Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma UN Wasko, J Jiang, A Curiel-Garcia, Y Wang, B Lee, M Orlen, ... bioRxiv, 2023 | 7 | 2023 |
| Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy M Singh, M Holderfield, B Lee, J Jiang, A Tomlinson, K Seamon, A Mira, ... | 5 | 2023 |
| Abstract ND03: Discovery of RMC-9805, an oral, covalent tri-complex KRASG12D (ON) inhibitor JE Knox, GL Burnett, C Weller, L Jiang, D Zhang, N Vita, A Marquez, ... Cancer Research 84 (7_Supplement), ND03-ND03, 2024 | 3 | 2024 |
| 300 (PB288): Combination of RAS (ON) Multi-Selective and G12D-Selective Inhibitors Improves Antitumor Activity and Enhances Antitumor Immunity in Preclinical Models of KRASG12D … L Jiang, M Menard, C Weller, GL Burnett, B Maldonato, Z Wang, SL Steele, ... European Journal of Cancer 211, 114814, 2024 | | 2024 |
| Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Cancer Research 84 (6_Supplement), 1927-1927, 2024 | | 2024 |
| Abstract B080: Mutant-selective KRASG12D(ON) inhibitor suppresses proliferation in vitro and tumor growth in vivo of KrasG12D GEMM-derived PDAC organoids MP Labrecque, L Jiang, N Nasholm, B Nayak, X Yu, A Song, C Weller, ... Cancer Research 84 (2_Supplement), B080-B080, 2024 | | 2024 |
| Mutant-selective KRASG12D (ON) inhibitor suppresses proliferation in vitro and tumor growth in vivo of KrasG12D GEMM-derived PDAC organoids MP Labrecque, L Jiang, N Nasholm, B Nayak, X Yu, A Song, C Weller, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |
