Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons D Janning, M Igaev, F Sündermann, J Brühmann, O Beutel, JJ Heinisch, ... Molecular biology of the cell 25 (22), 3541-3551, 2014 | 183 | 2014 |
Single-molecule imaging reveals dynamic biphasic partition of RNA-binding proteins in stress granules B Niewidok, M Igaev, A Pereira da Graca, A Strassner, C Lenzen, ... Journal of Cell Biology 217 (4), 1303-1318, 2018 | 124 | 2018 |
Automated cryo-EM structure refinement using correlation-driven molecular dynamics M Igaev, C Kutzner, LV Bock, AC Vaiana, H Grubmüller eLife 8, e43542, 2019 | 90 | 2019 |
Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge CL Lawson, A Kryshtafovych, PD Adams, PV Afonine, ML Baker, ... Nature methods 18 (2), 156-164, 2021 | 80 | 2021 |
SESCA: predicting circular dichroism spectra from protein molecular structures G Nagy, M Igaev, NC Jones, SV Hoffmann, H Grubmüller Journal of chemical theory and computation 15 (9), 5087-5102, 2019 | 75 | 2019 |
Presence of a carboxyterminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau's interaction with microtubules in axon-like processes B Niewidok, M Igaev, F Sündermann, D Janning, L Bakota, R Brandt Molecular Biology of the Cell, 2016 | 58 | 2016 |
Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43 A Gauthier-Kemper, M Igaev, F Sündermann, D Janning, J Brühmann, ... Molecular biology of the cell 25 (21), 3284-3299, 2014 | 53 | 2014 |
Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit M Igaev, H Grubmüller eLife 7, e34353, 2018 | 46 | 2018 |
A refined reaction-diffusion model of tau-microtubule dynamics and its application in FDAP analysis M Igaev, D Janning, F Sündermann, B Niewidok, R Brandt, W Junge Biophysical journal 107 (11), 2567-2578, 2014 | 46 | 2014 |
Choice of fluorophore affects dynamic DNA nanostructures K Jahnke, H Grubmüller, M Igaev, K Göpfrich Nucleic Acids Research 49 (7), 4186-4195, 2021 | 29 | 2021 |
Microtubule instability driven by longitudinal and lateral strain propagation M Igaev, H Grubmüller PLOS Computational Biology, 10.1371/journal.pcbi.1008132, 2020 | 25 | 2020 |
Bending-torsional elasticity and energetics of the plus-end microtubule tip M Igaev, H Grubmüller Proceedings of the National Academy of Sciences 119 (12), e2115516119, 2022 | 13 | 2022 |
Outcomes of the 2019 emdataresource model challenge: validation of cryo-em models at near-atomic resolution CL Lawson, A Kryshtafovych, PD Adams, PV Afonine, ML Baker, ... BioRxiv, 2020.06. 12.147033, 2020 | 8 | 2020 |
Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge CL Lawson, A Kryshtafovych, GD Pintilie, SK Burley, J Černý, VB Chen, ... Nature Methods 21, 1340-1348, 2024 | 1 | 2024 |
Estimation of microtubule-generated forces combining molecular dynamics and coarse-grained modeling M Kalutskii, H Grubmüller, M Igaev Biophysical Journal 123 (3), 190a, 2024 | | 2024 |
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match LV Bock, M Igaev, H Grubmüller Current Opinion in Structural Biology 86, 102825, 2024 | | 2024 |
Free energy along transition pathways from correlation based sampling E Pohjolainen, M Igaev, H Grubmuller, AC Vaiana Biophysical Journal 121 (3), 287a, 2022 | | 2022 |
Free Energy Along Transition Pathways from Structure Refinement Simulations E Pohjolainen, AC Vaiana, M Igaev, H Grubmuller Biophysical Journal 120 (3), 97a, 2021 | | 2021 |
Twist-Bending Elasticity and Energetics of the Plus-End Microtubule Tip Captured by Exascale Atomistic Simulations M Igaev, H Grubmueller Biophysical Journal 120 (3), 255a, 2021 | | 2021 |
Force generation by polymerizing and depolymerizing microtubules M Igaev, H Grubmüller High-performance computing and data science in the Max Planck Society, 52-54, 2021 | | 2021 |