The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines JE Gibbs, J Blaikley, S Beesley, L Matthews, KD Simpson, SH Boyce, ... Proceedings of the National Academy of Sciences 109 (2), 582-587, 2012 | 680 | 2012 |
Clocking in to immunity C Scheiermann, J Gibbs, L Ince, A Loudon Nature Reviews Immunology 18 (7), 423-437, 2018 | 439 | 2018 |
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action J Gibbs, L Ince, L Matthews, J Mei, T Bell, N Yang, B Saer, N Begley, ... Nature medicine 20 (8), 919-926, 2014 | 438 | 2014 |
Circadian dysfunction in disease DA Bechtold, JE Gibbs, ASI Loudon Trends in pharmacological sciences 31 (5), 191-198, 2010 | 276 | 2010 |
Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes QJ Meng, ES Maywood, DA Bechtold, WQ Lu, J Li, JE Gibbs, SM Dupré, ... Proceedings of the National Academy of Sciences 107 (34), 15240-15245, 2010 | 260 | 2010 |
The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis V Pekovic-Vaughan, J Gibbs, H Yoshitane, N Yang, D Pathiranage, B Guo, ... Genes & development 28 (6), 548-560, 2014 | 254 | 2014 |
Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation M Pariollaud, JE Gibbs, TW Hopwood, S Brown, N Begley, R Vonslow, ... The Journal of clinical investigation 128 (6), 2281-2296, 2018 | 160 | 2018 |
Circadian timing in the lung; a specific role for bronchiolar epithelial cells JE Gibbs, S Beesley, J Plumb, D Singh, S Farrow, DW Ray, ASI Loudon Endocrinology 150 (1), 268-276, 2009 | 150 | 2009 |
Ligand modulation of REV-ERBα function resets the peripheral circadian clock in a phasic manner QJ Meng, A McMaster, S Beesley, WQ Lu, J Gibbs, D Parks, J Collins, ... Journal of cell science 121 (21), 3629-3635, 2008 | 148 | 2008 |
Levetiracetam: antiepileptic properties and protective effects on mitochondrial dysfunction in experimental status epilepticus JE Gibbs, MC Walker, HR Cock Epilepsia 47 (3), 469-478, 2006 | 138 | 2006 |
The role of the circadian clock in rheumatoid arthritis JE Gibbs, DW Ray Arthritis research & therapy 15, 1-9, 2013 | 137 | 2013 |
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia GB Kitchen, PS Cunningham, TM Poolman, M Iqbal, R Maidstone, ... Proceedings of the National Academy of Sciences 117 (3), 1543-1551, 2020 | 117 | 2020 |
The circadian clock regulates inflammatory arthritis LE Hand, TW Hopwood, SH Dickson, AL Walker, ASI Loudon, DW Ray, ... The FASEB Journal 30 (11), 3759, 2016 | 108 | 2016 |
A matter of time: study of circadian clocks and their role in inflammation SJ Carter, HJ Durrington, JE Gibbs, J Blaikley, AS Loudon, DW Ray, ... Journal of Leucocyte Biology 99 (4), 549-560, 2016 | 86 | 2016 |
The distribution of the anti‐HIV drug, 2′ 3′‐dideoxycytidine (ddC), across the blood–brain and blood–cerebrospinal fluid barriers and the influence of organic anion transport … JE Gibbs, SA Thomas Journal of neurochemistry 80 (3), 392-404, 2002 | 80 | 2002 |
The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock TW Hopwood, S Hall, N Begley, R Forman, S Brown, R Vonslow, B Saer, ... Scientific reports 8 (1), 3782, 2018 | 78 | 2018 |
Depletion of reduced glutathione precedes inactivation of mitochondrial enzymes following limbic status epilepticus in the rat hippocampus H Sleven, JE Gibbs, S Heales, M Thom, HR Cock Neurochemistry international 48 (2), 75-82, 2006 | 76 | 2006 |
The circadian clock protein REVERBα inhibits pulmonary fibrosis development PS Cunningham, P Meijer, A Nazgiewicz, SG Anderson, LA Borthwick, ... Proceedings of the National Academy of Sciences 117 (2), 1139-1147, 2020 | 65 | 2020 |
Circadian rhythms in adaptive immunity P Downton, JO Early, JE Gibbs Immunology 161 (4), 268-277, 2020 | 63 | 2020 |
The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses C Anthonypillai, JE Gibbs, SA Thomas Cerebrospinal fluid research 3, 1-10, 2006 | 57 | 2006 |