The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo M Liu, V Bandaru, JP Bond, P Jaruga, X Zhao, PP Christov, CJ Burrows, ... Proceedings of the National Academy of Sciences 107 (11), 4925-4930, 2010 | 215 | 2010 |
Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration W Xu, AM Weissmiller, JA White, F Fang, X Wang, Y Wu, ML Pearn, ... The Journal of clinical investigation 126 (5), 1815-1833, 2016 | 170 | 2016 |
Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1 N Krishnamurthy, X Zhao, CJ Burrows, SS David Biochemistry 47 (27), 7137-7146, 2008 | 161 | 2008 |
Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling K Zhang, RFB Kenan, Y Osakada, W Xu, RS Sinit, L Chen, X Zhao, ... Journal of Neuroscience 33 (17), 7451-7462, 2013 | 106 | 2013 |
Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts X Zhao, N Krishnamurthy, CJ Burrows, SS David Biochemistry 49 (8), 1658-1666, 2010 | 105 | 2010 |
Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy Z Mo, X Zhao, H Liu, Q Hu, XQ Chen, J Pham, NA Wei, ZE Liu, J Zhou, ... Nature communications 9 (1), 1007, 2018 | 104 | 2018 |
TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease X Zhao, XQ Chen, E Han, Y Hu, P Paik, Z Ding, J Overman, AL Lau, ... Proceedings of the National Academy of Sciences 113 (38), E5655-E5664, 2016 | 98 | 2016 |
Amyloid-β peptide is a substrate of the human 20S proteasome X Zhao, J Yang ACS chemical neuroscience 1 (10), 655-660, 2010 | 79 | 2010 |
Design, synthesis and structure–activity relationship (SAR) studies of 2, 4-disubstituted pyrimidine derivatives: Dual activity as cholinesterase and Aβ-aggregation inhibitors T Mohamed, X Zhao, LK Habib, J Yang, PPN Rao Bioorganic & medicinal chemistry 19 (7), 2269-2281, 2011 | 66 | 2011 |
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts Y Guo, V Bandaru, P Jaruga, X Zhao, CJ Burrows, S Iwai, M Dizdaroglu, ... DNA repair 9 (2), 177-190, 2010 | 58 | 2010 |
Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease R Shen, X Zhao, L He, Y Ding, W Xu, S Lin, S Fang, W Yang, K Sung, ... Translational neurodegeneration 9, 1-19, 2020 | 45 | 2020 |
Human endonuclease VIII-like (NEIL) proteins in the giant DNA Mimivirus V Bandaru, X Zhao, MR Newton, CJ Burrows, SS Wallace DNA repair 6 (11), 1629-1641, 2007 | 44 | 2007 |
Real-time imaging of axonal transport of quantum dot-labeled BDNF in primary neurons X Zhao, Y Zhou, AM Weissmiller, ML Pearn, WC Mobley, C Wu JoVE (Journal of Visualized Experiments), e51899, 2014 | 41 | 2014 |
Swedish nerve growth factor mutation (NGFR100W) defines a role for TrkA and p75NTR in nociception K Sung, LF Ferrari, W Yang, CH Chung, X Zhao, Y Gu, S Lin, K Zhang, ... Journal of Neuroscience 38 (14), 3394-3413, 2018 | 37 | 2018 |
A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: Evidence for a role for APP AM Weissmiller, O Natera-Naranjo, SM Reyna, ML Pearn, X Zhao, ... PloS one 10 (2), e0118379, 2015 | 37 | 2015 |
Genetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein Z Ding, P German, S Bai, AS Reddy, XD Liu, M Sun, L Zhou, X Chen, ... Cancer research 74 (11), 3127-3136, 2014 | 25 | 2014 |
In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase X Zhao, JG Muller, M Halasyam, SS David, CJ Burrows Biochemistry 46 (12), 3734-3744, 2007 | 22 | 2007 |
Using TRiC or TRiC-Based Reagents to Prevent and Rescue Striatal Atrophy in Huntington Disease W Mobley, X Zhao, Z Babic, Y Gu, J Raus, C Wu ANNALS OF NEUROLOGY 84, S168-S168, 2018 | | 2018 |
Neurotrophic Signals, Axonal Transport of X Zhao, C Wu, WC Mobley Academic Press, 2014 | | 2014 |
Selective Up-Regulation of TRiC Subunit (s) Ameliorates mHtt Toxicity X Zhao, E Han, RF Ben Kenan, W Mobley, C Wu ANNALS OF NEUROLOGY 74, S66-S66, 2013 | | 2013 |