CTCF and cohesin regulate chromatin loop stability with distinct dynamics AS Hansen, I Pustova, C Cattoglio, R Tjian, X Darzacq Elife 6, e25776, 2017 | 547 | 2017 |
RNA polymerase II clustering through carboxy-terminal domain phase separation M Boehning, C Dugast-Darzacq, M Rankovic, AS Hansen, T Yu, ... Nature structural & molecular biology 25 (9), 833-840, 2018 | 528 | 2018 |
Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II H Lu, D Yu, AS Hansen, S Ganguly, R Liu, A Heckert, X Darzacq, Q Zhou Nature 558 (7709), 318-323, 2018 | 501 | 2018 |
Resolving the 3D landscape of transcription-linked mammalian chromatin folding THS Hsieh, C Cattoglio, E Slobodyanyuk, AS Hansen, OJ Rando, R Tjian, ... Molecular cell 78 (3), 539-553. e8, 2020 | 440 | 2020 |
A dynamic mode of mitotic bookmarking by transcription factors SS Teves, L An, AS Hansen, L Xie, X Darzacq, R Tjian eLife 5, e22280, 2016 | 261 | 2016 |
Recent evidence that TADs and chromatin loops are dynamic structures AS Hansen, C Cattoglio, X Darzacq, R Tjian Nucleus, 2017 | 259 | 2017 |
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation DT McSwiggen, AS Hansen, SS Teves, H Marie-Nelly, Y Hao, AB Heckert, ... eLife 8, e47098, 2019 | 238 | 2019 |
Dynamics of CTCF-and cohesin-mediated chromatin looping revealed by live-cell imaging M Gabriele, HB Brandão, S Grosse-Holz, A Jha, GM Dailey, C Cattoglio, ... Science 376 (6592), 496-501, 2022 | 237 | 2022 |
Robust model-based analysis of single-particle tracking experiments with Spot-On AS Hansen, M Woringer, JB Grimm, LD Lavis, R Tjian, X Darzacq eLife 7, e33125, 2018 | 236 | 2018 |
Distinct classes of chromatin loops revealed by deletion of an RNA-binding Region in CTCF AS Hansen, THS Hsieh, C Cattoglio, I Pustova, R Saldaña-Meyer, ... Molecular Cell, 2019 | 218 | 2019 |
Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expression AS Hansen, EK O’Shea Molecular systems biology 9 (1), 2013 | 170 | 2013 |
Enhancer–promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1 THS Hsieh, C Cattoglio, E Slobodyanyuk, AS Hansen, X Darzacq, R Tjian Nature Genetics 54 (12), 1919-1932, 2022 | 128 | 2022 |
Guided nuclear exploration increases CTCF target search efficiency AS Hansen, A Amitai, C Cattoglio, R Tjian, X Darzacq Nature Chemical Biology, 1-10, 2019 | 121 | 2019 |
CTCF sites display cell cycle–dependent dynamics in factor binding and nucleosome positioning ME Oomen, AS Hansen, Y Liu, X Darzacq, J Dekker Genome research 29 (2), 236-249, 2019 | 120 | 2019 |
Limits on information transduction through amplitude and frequency regulation of transcription factor activity AS Hansen, EK O'Shea elife 4, e06559, 2015 | 115 | 2015 |
Determining cellular CTCF and cohesin abundances to constrain 3D genome models C Cattoglio, I Pustova, N Walther, JJ Ho, M Hantsche-Grininger, ... Elife 8, e40164, 2019 | 108 | 2019 |
High-throughput microfluidics to control and measure signaling dynamics in single yeast cells AS Hansen, N Hao, EK O'shea Nature protocols 10 (8), 1181-1197, 2015 | 104 | 2015 |
Control of Olefin Geometry in Macrocyclic Ring-Closing Metathesis Using a Removable Silyl Group Y Wang, M Jimenez, AS Hansen, EA Raiber, SL Schreiber, DW Young Journal of the American Chemical Society, 2011 | 81 | 2011 |
CTCF as a boundary factor for cohesin-mediated loop extrusion: evidence for a multi-step mechanism AS Hansen Nucleus 11 (1), 132-148, 2020 | 78 | 2020 |
Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation A Thalhammer, AS Hansen, AH El-Sagheer, T Brown, CJ Schofield Chemical Communications 47 (18), 5325-5327, 2011 | 78 | 2011 |