Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry WH Guo, X Qi, X Yu, Y Liu, CI Chung, F Bai, X Lin, D Lu, L Wang, J Chen, ... Nature communications 11 (1), 4268, 2020 | 165 | 2020 |
Dihydromyricetin protects the liver via changes in lipid metabolism and enhanced ethanol metabolism J Silva, X Yu, R Moradian, C Folk, MH Spatz, P Kim, AA Bhatti, DL Davies, ... Alcoholism: Clinical and Experimental Research 44 (5), 1046-1060, 2020 | 70 | 2020 |
Applications of covalent chemistry in targeted protein degradation D Lu, X Yu, H Lin, R Cheng, EY Monroy, X Qi, MC Wang, J Wang Chemical Society Reviews 51 (22), 9243-9261, 2022 | 29 | 2022 |
Discovery of a potent BTK and IKZF1/3 triple degrader through reversible covalent BTK PROTAC development X Yu, WH Guo, H Lin, R Cheng, EY Monroy, F Jin, L Ding, D Lu, X Qi, ... Current research in chemical biology 2, 100029, 2022 | 12 | 2022 |
Antialcohol effects of dihydromyricetin in combination with other flavonoids J Silva, X Yu, L Qi, DL Davies, J Liang Natural Product Communications 15 (8), 1934578X20946250, 2020 | 10 | 2020 |
Quantitative measurement of PROTAC intracellular accumulation X Yu, J Wang Methods in enzymology 681, 189-214, 2023 | 4 | 2023 |
Development of Biochemical and Cellular Probes to Study RIPK1 Target Engagement X Yu, H Lin, F Li, J Wang, D Lu ACS Medicinal Chemistry Letters, 2024 | 3 | 2024 |
Development of a First-in-Class RIPK1 Degrader to Enhance Antitumor Immunity X Yu, D Lu, J Wang bioRxiv, 2024.03. 25.586133, 2024 | 3 | 2024 |
Lead Compound Development of SRC-3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy D Lu, J Chen, L Qin, I Bijou, P Yi, F Li, X Song, KR MacKenzie, X Yu, ... Journal of medicinal chemistry 67 (7), 5333-5350, 2024 | 2 | 2024 |
Development of a RIPK1 degrader to enhance antitumor immunity X Yu, D Lu, X Qi, RR Paudel, H Lin, BL Holloman, F Jin, L Xu, L Ding, ... Nature Communications 15 (1), 1-14, 2024 | | 2024 |
Death-associated protein kinase 3 modulates migration and invasion of triple-negative breast cancer cells J Wang, AM Tran-Huynh, BJ Kim, DW Chan, MV Holt, D Fandino, X Yu, ... PNAS nexus 3 (9), pgae401, 2024 | | 2024 |
Development of a First-in-Class RIPK1 Degrader to Enhance Antitumor Immunity J Wang, D Lu, X Yu, X Qi, H Lin, BL Holloman, F Jin, L Xu, L Ding, W Peng, ... Research Square, 2024 | | 2024 |
Chemical Induction of Longevity-Promoting Colanic Acid in the Host's Microbiota G Hu, MB Cooke, AX Wen, X Yu, J Wang, C Herman, MC Wang bioRxiv, 2024.07. 23.604802, 2024 | | 2024 |
Quantification of glutathione with high throughput live-cell imaging X Qi, J Chen, X Jiang, D Lu, X Yu, H Lin, EY Monroy, MC Wang, J Wang bioRxiv, 2023.07. 11.548586, 2023 | | 2023 |