| Biochar characteristics relate to its utility as an alternative soil inoculum carrier to peat and vermiculite L Hale, M Luth, D Crowley Soil Biology and Biochemistry 81, 228-235, 2015 | 177 | 2015 |
| Open-source discovery of chemical leads for next-generation chemoprotective antimalarials Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ... Science 362 (6419), eaat9446, 2018 | 112 | 2018 |
| Evaluation of pinewood biochar as a carrier of bacterial strain Enterobacter cloacae UW5 for soil inoculation L Hale, M Luth, R Kenney, D Crowley Applied Soil Ecology 84, 192-199, 2014 | 109 | 2014 |
| Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery MR Luth, P Gupta, S Ottilie, EA Winzeler ACS infectious diseases 4 (3), 301-314, 2018 | 78 | 2018 |
| Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial … BH Stokes, E Yoo, JM Murithi, MR Luth, P Afanasyev, PCA da Fonseca, ... PLoS pathogens 15 (6), e1007722, 2019 | 66 | 2019 |
| Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome SC Xie, DL Gillett, NJ Spillman, C Tsu, MR Luth, S Ottilie, S Duffy, ... Journal of medicinal chemistry 61 (22), 10053-10066, 2018 | 65 | 2018 |
| CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM) A Debnath, CM Calvet, G Jennings, W Zhou, A Aksenov, MR Luth, ... PLoS neglected tropical diseases 11 (12), e0006104, 2017 | 59 | 2017 |
| Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ... Cell chemical biology 29 (2), 191-201. e8, 2022 | 49 | 2022 |
| Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii A Rosenberg, MR Luth, EA Winzeler, M Behnke, LD Sibley Proceedings of the National Academy of Sciences 116 (52), 26881-26891, 2019 | 39 | 2019 |
| In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model REK Mandt, MJ Lafuente-Monasterio, T Sakata-Kato, MR Luth, D Segura, ... Science translational medicine 11 (521), eaav1636, 2019 | 38 | 2019 |
| Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy SC Xie, RD Metcalfe, E Dunn, CJ Morton, SC Huang, T Puhalovich, Y Du, ... Science 376 (6597), 1074-1079, 2022 | 35 | 2022 |
| Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway GM LaMonte, F Rocamora, DS Marapana, NF Gnädig, S Ottilie, MR Luth, ... Nature communications 11 (1), 1780, 2020 | 33 | 2020 |
| Probing the open global health chemical diversity library for multistage-active starting points for next-generation antimalarials M Abraham, K Gagaring, ML Martino, M Vanaerschot, DM Plouffe, J Calla, ... ACS Infectious Diseases 6 (4), 613-628, 2020 | 27 | 2020 |
| Efficacy of post-harvest rinsing and bleach disinfection of E. coli O157: H7 on spinach leaf surfaces NM Kinsinger, HM Mayton, MR Luth, SL Walker Food microbiology 62, 212-220, 2017 | 20 | 2017 |
| The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages LB Arendse, JM Murithi, T Qahash, CFA Pasaje, LC Godoy, S Dey, ... Science translational medicine 14 (667), eabo7219, 2022 | 19 | 2022 |
| Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum K Kümpornsin, T Kochakarn, T Yeo, J Okombo, MR Luth, J Hoshizaki, ... Nature Communications 14 (1), 3059, 2023 | 14 | 2023 |
| PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum F Rocamora, P Gupta, ES Istvan, MR Luth, EF Carpenter, K Kümpornsin, ... ACS Infectious Diseases 7 (4), 811-825, 2021 | 14 | 2021 |
| Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance MA Tye, NC Payne, C Johansson, K Singh, SA Santos, L Fagbami, A Pant, ... Nature Communications 13 (1), 4976, 2022 | 13 | 2022 |
| Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target ES Istvan, F Guerra, M Abraham, KS Huang, F Rocamora, H Zhao, L Xu, ... Science translational medicine 15 (686), eadc9249, 2023 | 10 | 2023 |
| Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance S Ottilie, MR Luth, E Hellemann, GM Goldgof, E Vigil, P Kumar, ... Communications Biology 5 (1), 128, 2022 | 10 | 2022 |
