| Neurological abnormalities in a knock-in mouse model of Huntington’s disease CH Lin, S Tallaksen-Greene, WM Chien, JA Cearley, WS Jackson, ... Human molecular genetics 10 (2), 137-144, 2001 | 664 | 2001 |
| Intraflagellar transport is essential for endochondral bone formation CJ Haycraft, Q Zhang, B Song, WS Jackson, PJ Detloff, R Serra, BK Yoder Oxford University Press for The Company of Biologists Limited 134 (2), 307-316, 2007 | 418 | 2007 |
| The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases AD Steele, WS Jackson, OD King, S Lindquist Proceedings of the National Academy of Sciences 104 (6), 1983-1988, 2007 | 215 | 2007 |
| Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice WS Jackson, AW Borkowski, H Faas, AD Steele, OD King, N Watson, ... Neuron 63 (4), 438-450, 2009 | 183 | 2009 |
| Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice K Xie, DP Ryan, BL Pearson, KS Henzel, F Neff, RO Vidal, M Hennion, ... Proceedings of the National Academy of Sciences 115 (10), E2348-E2357, 2018 | 124 | 2018 |
| Stroke target identification guided by astrocyte transcriptome analysis C Rakers, M Schleif, N Blank, H Matušková, T Ulas, K Händler, SV Torres, ... Glia 67 (4), 619-633, 2019 | 103 | 2019 |
| Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein WS Jackson Disease models & mechanisms 7 (1), 21-29, 2014 | 92 | 2014 |
| Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease AD Steele, G Hutter, WS Jackson, FL Heppner, AW Borkowski, OD King, ... Proceedings of the National Academy of Sciences 105 (36), 13626-13631, 2008 | 79 | 2008 |
| Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases WS Jackson, AW Borkowski, NE Watson, OD King, H Faas, A Jasanoff, ... Proceedings of the National Academy of Sciences 110 (36), 14759-14764, 2013 | 69 | 2013 |
| Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas M Heikenwalder, MO Kurrer, I Margalith, J Kranich, N Zeller, J Haybaeck, ... Immunity 29 (6), 998-1008, 2008 | 69 | 2008 |
| Memory trace interference impairs recall in a mouse model of Alzheimer’s disease S Poll, M Mittag, F Musacchio, LC Justus, EA Giovannetti, J Steffen, ... Nature neuroscience 23 (8), 952-958, 2020 | 62 | 2020 |
| Prion pathogenesis is independent of caspase-12 AD Steele, C Hetz, CH Yi, WS Jackson, AW Borkowski, J Yuan, ... Prion 1 (4), 243-247, 2007 | 60 | 2007 |
| Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein L Linsenmeier, B Mohammadi, S Wetzel, B Puig, WS Jackson, ... Molecular neurodegeneration 13, 1-17, 2018 | 57 | 2018 |
| Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo AD Steele, OD King, WS Jackson, CA Hetz, AW Borkowski, P Thielen, ... Journal of Neuroscience 27 (47), 13022-13027, 2007 | 47 | 2007 |
| Context dependent neuroprotective properties of prion protein (PrP) AD Steele, Z Zhou, WS Jackson, C Zhu, P Auluck, MA Moskowitz, ... Prion 3 (4), 240-249, 2009 | 37 | 2009 |
| Nucleocytoplasmic transport signals affect the age at onset of abnormalities in knock-in mice expressing polyglutamine within an ectopic protein context WS Jackson, SJ Tallaksen-Greene, RL Albin, PJ Detloff Human Molecular Genetics 12 (13), 1621-1629, 2003 | 37 | 2003 |
| Manipulating the prion protein gene sequence and expression levels with CRISPR/Cas9 L Kaczmarczyk, Y Mende, B Zevnik, WS Jackson PloS one 11 (4), e0154604, 2016 | 31 | 2016 |
| Requirements for mutant and wild-type prion protein misfolding in vitro GP Noble, DJ Walsh, MB Miller, WS Jackson, S Supattapone Biochemistry 54 (5), 1180-1187, 2015 | 23 | 2015 |
| Astonishing advances in mouse genetic tools for biomedical research WS Jackson, L Kaczmarczyk Swiss medical weekly 145 (4344), w14186-w14186, 2015 | 20 | 2015 |
| Translation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brain WS Jackson, C Krost, AW Borkowski, L Kaczmarczyk PLoS One 9 (4), e95958, 2014 | 17 | 2014 |
