| Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes D Helmlinger, S Hardy, S Sasorith, F Klein, F Robert, C Weber, L Miguet, ... Human molecular genetics 13 (12), 1257-1265, 2004 | 276 | 2004 |
| Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction D Helmlinger, S Hardy, G Abou-Sleymane, A Eberlin, AB Bowman, ... PLoS biology 4 (3), e67, 2006 | 183 | 2006 |
| Sharing the SAGA D Helmlinger, L Tora Trends in biochemical sciences 42 (11), 850-861, 2017 | 182 | 2017 |
| SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types G Yvert, KS Lindenberg, D Devys, D Helmlinger, GB Landwehrmeyer, ... Human molecular genetics 10 (16), 1679-1692, 2001 | 113 | 2001 |
| The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8 D Helmlinger, S Marguerat, J Villén, SP Gygi, J Bähler, F Winston Genes & development 22 (22), 3184-3195, 2008 | 111 | 2008 |
| Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice D Helmlinger, G Yvert, S Picaud, K Merienne, J Sahel, JL Mandel, ... Human molecular genetics 11 (26), 3351-3359, 2002 | 100 | 2002 |
| Tra1 has specific regulatory roles, rather than global functions, within the SAGA co‐activator complex D Helmlinger, S Marguerat, J Villén, DL Swaney, SP Gygi, J Bähler, ... The EMBO Journal 30 (14), 2843-2852, 2011 | 87 | 2011 |
| Polyglutamine expansion induces a protein-damaging stress connecting heat shock protein 70 to the JNK pathway K Merienne, D Helmlinger, GR Perkin, D Devys, Y Trottier Journal of Biological Chemistry 278 (19), 16957-16967, 2003 | 85 | 2003 |
| Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program G Abou-Sleymane, F Chalmel, D Helmlinger, A Lardenois, C Thibault, ... Human molecular genetics 15 (5), 691-703, 2006 | 83 | 2006 |
| Transcriptional alterations and chromatin remodeling in polyglutamine diseases D Helmlinger, L Tora, D Devys TRENDS in Genetics 22 (10), 562-570, 2006 | 71 | 2006 |
| Retinal cell type expression specificity of HIV‐1‐derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter AP Bemelmans, S Bonnel, L Houhou, N Dufour, E Nandrot, D Helmlinger, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 59 | 2005 |
| Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model D Helmlinger, G Abou-Sleymane, G Yvert, S Rousseau, C Weber, ... Journal of Neuroscience 24 (8), 1881-1887, 2004 | 58 | 2004 |
| Hsp70 and Hsp40 Chaperones Do Not Modulate Retinal Phenotype in SCA7 Mice*♦ D Helmlinger, J Bonnet, JL Mandel, Y Trottier, D Devys Journal of Biological Chemistry 279 (53), 55969-55977, 2004 | 45 | 2004 |
| TORC1 and TORC2 converge to regulate the SAGA co‐activator in response to nutrient availability T Laboucarié, D Detilleux, RA Rodriguez‐Mias, C Faux, Y Romeo, ... EMBO reports 18 (12), 2197-2218, 2017 | 44 | 2017 |
| The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes A Elías-Villalobos, A Fernández-Álvarez, I Moreno-Sánchez, ... PLoS pathogens 11 (8), e1005134, 2015 | 43 | 2015 |
| Both normal and polyglutamine-expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase-containing complexes D Helmlinger, S Hardy, A Eberlin, D Devys, L Tora Biochemical Society Symposia 73, 155-163, 2006 | 43 | 2006 |
| What do the structures of GCN5-containing complexes teach us about their function? D Helmlinger, G Papai, D Devys, L Tora Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1864 (2), 194614, 2021 | 35 | 2021 |
| Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast A Elías-Villalobos, D Toullec, C Faux, M Séveno, D Helmlinger Nature Communications 10 (1), 5237, 2019 | 33 | 2019 |
| New insights into the evolutionary conservation of the sole PIKK pseudokinase Tra1/TRRAP A Elías-Villalobos, P Fort, D Helmlinger Biochemical Society Transactions 47 (6), 1597-1608, 2019 | 27 | 2019 |
| Long-term engraftment of systemically transplanted, gene-modified bone marrow-derived cells in the adult mouse retina C Boettcher, E Ulbricht, D Helmlinger, AF Mack, A Reichenbach, ... British journal of ophthalmology 92 (2), 272-275, 2008 | 17 | 2008 |
