A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA M Woodson, J Pajak, BP Mahler, W Zhao, W Zhang, G Arya, MA White, ... Science Advances 7 (19), eabc1955, 2021 | 40 | 2021 |
Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader C Gaubitz, X Liu, J Pajak, NP Stone, JA Hayes, G Demo, BA Kelch Elife 11, e74175, 2022 | 31 | 2022 |
Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes V Simões, BK Cizubu, L Harley, Y Zhou, J Pajak, NA Snyder, J Bouvette, ... Cell reports 39 (8), 2022 | 16* | 2022 |
Functional dissection of a viral DNA packaging Machine's Walker B Motif D Ortiz, M Ordyan, J Pajak, J Sippy, A Catala, CS Oh, A Vu, G Arya, ... Journal of molecular biology 431 (22), 4455-4474, 2019 | 16 | 2019 |
Interaction of PCL based self-assembled nano-polymeric micelles with model lipid bilayers using coarse-grained molecular dynamics simulations AS Raman, J Pajak, YC Chiew Chemical physics letters 712, 1-6, 2018 | 16 | 2018 |
Evidence that a catalytic glutamate and an ‘Arginine Toggle’ act in concert to mediate ATP hydrolysis and mechanochemical coupling in a viral DNA packaging motor D Ortiz, D delToro, M Ordyan, J Pajak, J Sippy, A Catala, CS Oh, A Vu, ... Nucleic acids research 47 (3), 1404-1415, 2018 | 15 | 2018 |
Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor J Pajak, E Dill, E Reyes-Aldrete, MA White, BA Kelch, PJ Jardine, G Arya, ... Nucleic acids research 49 (11), 6474-6488, 2021 | 14 | 2021 |
Viral packaging ATPases utilize a glutamate switch to couple ATPase activity and DNA translocation J Pajak, R Atz, BJ Hilbert, MC Morais, BA Kelch, PJ Jardine, G Arya Proceedings of the National Academy of Sciences 118 (17), e2024928118, 2021 | 11 | 2021 |
A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA X Liu, C Gaubitz, J Pajak, BA Kelch Elife 11, e77483, 2022 | 9 | 2022 |
Biophysics of DNA packaging J Pajak, G Arya, DE Smith Academic Press, 2021 | 7 | 2021 |
Conformational dynamics control assembly of an extremely long bacteriophage tail tube E Agnello, J Pajak, X Liu, BA Kelch Journal of Biological Chemistry 299 (3), 2023 | 4 | 2023 |
Molecular dynamics of DNA translocation by FtsK J Pajak, G Arya Nucleic Acids Research 50 (15), 8459-8470, 2022 | 1 | 2022 |
Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication JT Landeck, J Pajak, EK Norman, EL Sedivy, BA Kelch Journal of Biological Chemistry 300 (4), 2024 | | 2024 |