Finishing the euchromatic sequence of the human genome International Human Genome Sequencing Consortium Nature 431 (7011), 931-945, 2004 | 5210 | 2004 |
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ... Cell 149 (5), 1008-1022, 2012 | 509 | 2012 |
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ... The EMBO journal 35 (8), 831-844, 2016 | 240 | 2016 |
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling AL Hansen, GJ Buchan, M Rühl, K Mukai, SR Salvatore, E Ogawa, ... Proceedings of the National Academy of Sciences 115 (33), E7768-E7775, 2018 | 191 | 2018 |
Accurate and reliable high-throughput detection of copy number variation in the human genome H Fiegler, R Redon, D Andrews, C Scott, R Andrews, C Carder, R Clark, ... Genome research 16 (12), 1566-1574, 2006 | 185 | 2006 |
RNA: DNA hybrids are a novel molecular pattern sensed by TLR 9 RE Rigby, LM Webb, KJ Mackenzie, Y Li, A Leitch, MAM Reijns, ... The EMBO journal 33 (6), 542-558, 2014 | 172 | 2014 |
SAMHD1‐dependent retroviral control and escape in mice J Rehwinkel, J Maelfait, A Bridgeman, R Rigby, B Hayward, RA Liberatore, ... The EMBO journal 32 (18), 2454-2462, 2013 | 159 | 2013 |
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid JLO Pohjoismäki, JB Holmes, SR Wood, MY Yang, T Yasukawa, A Reyes, ... Journal of molecular biology 397 (5), 1144-1155, 2010 | 151 | 2010 |
Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling J Hertzog, AG Dias Junior, RE Rigby, CL Donald, A Mayer, E Sezgin, ... European journal of immunology 48 (7), 1120-1136, 2018 | 137 | 2018 |
RNA degradation in antiviral immunity and autoimmunity RE Rigby, J Rehwinkel Trends in immunology 36 (3), 179-188, 2015 | 88 | 2015 |
Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses Q Tang, RE Rigby, GR Young, AK Hvidt, T Davis, TK Tan, A Bridgeman, ... Immunity 54 (9), 1961-1975. e5, 2021 | 76 | 2021 |
Nucleic acid‐mediated inflammatory diseases RE Rigby, A Leitch, AP Jackson Bioessays 30 (9), 833-842, 2008 | 51 | 2008 |
Multi-modal characterization of monocytes in idiopathic pulmonary fibrosis reveals a primed type I interferon immune phenotype E Fraser, L Denney, A Antanaviciute, K Blirando, C Vuppusetty, Y Zheng, ... Frontiers in Immunology 12, 623430, 2021 | 41 | 2021 |
Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS J Hertzog, W Zhou, G Fowler, RE Rigby, A Bridgeman, HTW Blest, C Cursi, ... The EMBO journal 41 (14), e109217, 2022 | 32 | 2022 |
PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection RE Rigby, HM Wise, N Smith, P Digard, J Rehwinkel Scientific reports 9 (1), 7216, 2019 | 29 | 2019 |
Deoxyguanosine is a TLR7 agonist T Davenne, A Bridgeman, RE Rigby, J Rehwinkel European journal of immunology 50 (1), 56-62, 2020 | 25 | 2020 |
SAMHD1 limits the efficacy of forodesine in leukemia by protecting cells against the cytotoxicity of dGTP T Davenne, J Klintman, S Sharma, RE Rigby, HTW Blest, C Cursi, ... Cell reports 31 (6), 2020 | 22 | 2020 |
Fractional response analysis reveals logarithmic cytokine responses in cellular populations K Nienałtowski, RE Rigby, J Walczak, KE Zakrzewska, E Głów, ... Nature Communications 12 (1), 4175, 2021 | 8 | 2021 |
Recognition of Z-RNA by ADAR1 limits interferon responses Q Tang, RE Rigby, GR Young, A Korning-Hvidt, TK Tan, A Bridgeman, ... bioRxiv, 2020.12. 04.411793, 2020 | 5 | 2020 |
Typ-1-Interferonopathien V Tüngler, M Lee-Kirsch Arthritis und Rheuma 34 (04), 225-233, 2014 | 3 | 2014 |