Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4417 | 2013 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2273 | 2019 |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2164 | 2011 |
The genetic architecture of type 2 diabetes C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ... Nature 536 (7614), 41-47, 2016 | 1248 | 2016 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1022 | 2022 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 922 | 2017 |
Seven new loci associated with age-related macular degeneration Nature genetics 45 (4), 433-439, 2013 | 862 | 2013 |
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes G Jun, AC Naj, GW Beecham, LS Wang, J Buros, PJ Gallins, JD Buxbaum, ... Archives of neurology 67 (12), 1473-1484, 2010 | 503 | 2010 |
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4, and the risk of late-onset Alzheimer disease in African Americans C Reitz, G Jun, A Naj, R Rajbhandary, BN Vardarajan, LS Wang, ... Jama 309 (14), 1483-1492, 2013 | 466 | 2013 |
Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report JF Arboleda-Velasquez, F Lopera, M O’Hare, S Delgado-Tirado, C Marino, ... Nature medicine 25 (11), 1680-1683, 2019 | 445 | 2019 |
Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study EM Reiman, JF Arboleda-Velasquez, YT Quiroz, MJ Huentelman, ... Nature communications 11 (1), 667, 2020 | 315 | 2020 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 291 | 2016 |
Genome-wide association study of Alzheimer's disease MI Kamboh, FY Demirci, X Wang, RL Minster, MM Carrasquillo, ... Translational psychiatry 2 (5), e117-e117, 2012 | 290 | 2012 |
Assessment of the genetic variance of late-onset Alzheimer's disease PG Ridge, KB Hoyt, K Boehme, S Mukherjee, PK Crane, JL Haines, ... Neurobiology of aging 41, 200. e13-200. e20, 2016 | 258 | 2016 |
Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration SK Iyengar, D Song, BEK Klein, R Klein, JH Schick, J Humphrey, ... The American Journal of Human Genetics 74 (1), 20-39, 2004 | 223 | 2004 |
SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians A Miyashita, A Koike, G Jun, LS Wang, S Takahashi, E Matsubara, ... PloS one 8 (4), e58618, 2013 | 220 | 2013 |
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study AC Naj, G Jun, C Reitz, BW Kunkle, W Perry, YS Park, GW Beecham, ... JAMA neurology 71 (11), 1394-1404, 2014 | 204 | 2014 |
Transethnic genome‐wide scan identifies novel Alzheimer's disease loci GR Jun, J Chung, J Mez, R Barber, GW Beecham, DA Bennett, ... Alzheimer's & Dementia 13 (7), 727-738, 2017 | 187 | 2017 |
Novel Alzheimer disease risk loci and pathways in African American individuals using the African genome resources panel: a meta-analysis BW Kunkle, M Schmidt, HU Klein, AC Naj, KL Hamilton-Nelson, ... JAMA neurology 78 (1), 102-113, 2021 | 178 | 2021 |
EPHA2 Is Associated with Age-Related Cortical Cataract in Mice and Humans G Jun, H Guo, BEK Klein, R Klein, JJ Wang, P Mitchell, H Miao, KE Lee, ... PLoS genetics 5 (7), e1000584, 2009 | 168 | 2009 |